Publications
The following list includes all academic publications that list Kavli INsD among the authors' institutional affiliations. It is not a comprehensive list of all publications by all Kavli members. For complete lists of publications from each researcher in the Kavli INsD, please refer to each researcher's own website.
Scientists are growing human brain tissue in living mice – could this make their welfare harder to assess?
Graham, M
October 2026 | Article | The Conversation | Read
Molecular insights into GPR55 modulation reveal an atypical activation mechanism and glycosylation-dependent efficacy regulation
Claff T, Demalgiriya-Gamage C, Mahardhika AB, Stamos NA, Bangnowski F, Sun X, Dürr KL, Robinson CV, Haney R, Frego L, Nar H, Müller CE, Ebenhoch R, Kley JT, Weichert D
October 2026 | Journal Article | Nature Communications | Read
The Electrosolvation Effect: The Medium Is the Message
Wang S, Behjatian A, Le A, Zhu X, Krishnan M
October 2026 | Journal Article | Langmuir: the ACS journal of surfaces and colloids | Read
DNA Nanoglue: Silver Nanocluster-Based Cross-Linking of Supramolecular DNA Architectures
Nam K, Nagda R, Yadavalli HC, Kim YM, Yang K, Oh J, Kim TH, Stevens MM, Luo D, Shah P, Yang SW, Roh YH
October 2026 | Journal Article | ACS Nano | Read
Cryo-EM sample preparation with soft-landing and laser flash melting
Barrass SV, Esser TK, Mowry NJ, Eriksson L, Wenz J, Seeley LT, Curtis WA, Baker LA, Drabbels M, Rauschenbach S, Lorenz UJ
October 2026 | Journal Article | Nature Communications | Read
Extracellular vesicle α-synuclein topology reveals disease-associated conformers in brain and blood
Dutta S, Atashgaran A, Sahoo A, Chatzimichail S, Kapanidis AN, Tofaris GK
October 2026 | Journal Article (online ahead of print) | Brain: A Journal of Neurology | Read
Structural mechanism of TRPC3 inhibition by a potent antagonist
Collingridge J, Cole BA, Rowlett MA, Liddle J, Gatfield KM, Biggin PC, Becker E
October 2026 | Journal Article (Online ahead of print) | The Journal of Biological Chemistry | Read
Dynamic hinge-motion of PfRIPR revealed by malaria invasion inhibitory antibodies
Farrell B, Cooper AJR, Butkeviciute E, Wang LT, Egerton-Warburton E, Tan J, Higgins MK
October 2026 | Journal Article | Nature Communications | Read
Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing
Hazra JP, Andrews R, Turner P, Zhao Q, Steuer H, El-Sagheer AH, Mazumder A, El Sayyed H, Kümmerlin M, Brown T, Kapanidis AN
October 2026 | Journal Article | Nature Communications | Read
Human microglia clear intraneuronal α-synuclein aggregates by GPNMB-mediated trogocytosis
Chueh HJ, Katsikoudi A, Aragón-González A, Lam CL, Tamon L, Jainarayanan A, Agarwal D, Cowley SA, Sims D, Tofaris GK
October 2026 | Journal Article | Science Translational Medicine | Read
Harnessing prophylactic vaccines for targeted cancer immunotherapy by phage-guided delivery of cognate antigens to tumors
Waramit S, Suwan K, Küçük A, Benjathummarak S, Cencioni MT, Ashfield R, Gay L, Draper SJ, Hajitou A
October 2026 | Journal Article | Biomaterials | Read
Virus-like particle display of consensus α-neurotoxins does not enhance neutralising antibody responses against elapid venoms
Edge RJ, Patel RN, Stars EL, Wilkinson MC, Storm J, Dawson CA, Albulescu LO, King LDW, Casewell NR, Draper SJ, Ainsworth S
October 2026 | Journal Article | Vaccine | Read
Electronic profiling of neuronal extracellular vesicles enables early prediction of Parkinson's disease
Chang T, Jiang C, Yan S, Wustoni S, Salvigni L, Almaghrabi R, Hu MT, Tofaris GK, Guo K, Inal S
October 2026 | Journal Article | Science advances | Read
Ubiquitin chain editing promotes p97/VCP-dependent removal of RPA from DNA
Drake M, Zhou X, McStea A, Foster B, Chong KY, Attwood M, Roca Burgos L, Bennett L, Anand S, Kaplan M, Lu JJ, Ravikumar V, Fournier M, Navarro-Guerrero E, Ranes M, Struwe WB, Staples C, Ebner D, Gibbs-Seymour I
October 2026 | Journal Article | Molecular cell | Read
Cross-reactive Bundibugyo antibody responses in Guinean survivors of Ebola virus and recipients of rVSVΔG-ZEBOV-GP (Ervebo) in an outbreak setting
Hood G, Bore JA, Nguyen D, Struwe W, Carroll M
October 2026 | Journal Article | The Lancet. Infectious diseases | Read
Mapping Retinal Gene Expression to Cell Classes: Insights into Retinal Circadian Rhythms
Buckland J, Gilhooley MJ, Hankins MW, Semo M, Peirson SN
September 2026 | Journal Article | Clocks & Sleep | Read
A conserved conformation-dependent mechanism for the TREK two-pore domain potassium channel inhibitors carvedilol and fluphenazine
Reich J, Riegelhaupt PM, Tucker SJ, McClenaghan C
September 2026 | Journal Article (online ahead of print) | Molecular pharmacology | Read
Kirigami-Inspired Deployable Microneedle Robot With Enhanced Conformability for Targeted Oral Drug Delivery
Zhou K, Sun R, Zuo Y, Peeler DJ, Yeow J, Xie R, Lin J, Ma Y, Shao Y, Cao Y, Chen Z, Stevens MM
September 2026 | Journal Article (online ahead of print) | Small | Read
Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep
Meijer EJ, Mueller M, Krone LB, Yamagata T, Hoerder-Suabedissen A, Wilcox S, Alfonsa H, Chakrabarty A, Guidi L, Oliver PL, Vyazovskiy VV, Molnar Z
September 2026 | Journal Article | eLife | Read
Equivalent gain-of-function variants in KCNK3 and KCNK9 and their contribution to distinct TASK K2P channelopathies
Crowther KM, Jouen-Tachoire TRH, Proks P, Hall PR, Veale EL, Sörmann J, Rödström KEJ, Müller T, Wortmann SB, Barisic N, Hauser N, Salpietro V, Forsyth R, Williams L, Derrabi N, Bacino CA, Rosenfeld JA, Houlden H, Newstead S, Wright CF, Fasham J, Mathie AA, Maroofian R, Tucker SJ
September 2026 | Journal Article | The Journal of general physiology | Read
Molecular-level observation of the self-assembly of a virus-like particle
Asor R, Loewenthal D, Melnyk D, Tan TK, Kukura P
September 2026 | Journal Article | Nature | Read
Multi-spin control from one-spin pulses
Lim S, Guo B, Turner AL, Buchanan C, Baldwin AJ, Jones JA
September 2026 | Journal Article | Journal of magnetic resonance | Read
Image-guided optimization of regenerative graft attachment to the heart
Feng Z, Hachim D, Mylonaki I, Colzani M, Bettini A, Dondi C, Obregon-Gomez I, Lin J, Gambardella L, Bayraktar S, Deniszczyc E, Pope C, Saccoh AF, Ahmed E, Lythgoe MF, Kalber TL, Patrick PS, Sinha S, Stevens MM, Stuckey DJ
September 2026 | Journal Article | Biomaterials | Read
Microglia in C9orf72-associated amyotrophic lateral sclerosis: More or less active?
Vahsen BF, Pasterkamp RJ
September 2026 | Journal Article (online ahead of print) | Neural regeneration research | Read
Differential lipid selectivity of StARD phospholipid transporters revealed by native MS.
Kirschbaum C, Lawrence SAS, Bennett JL, Ramsay OB, Ahmed Y, El-Baba TJ, Vanni S, Robinson CV.
Nat Commun. 2026 Aug 22;17(1):10054. doi: 10.1038/s41467-026-76988-1.
August 2026 | Journal Article (online ahead of print) | Nature communications | Read
Label-free biochemical imaging and time point analysis of neural organoids via deep learning-enhanced Raman microspectroscopy.
Georgiev D, Xie R, Reumann D, Zhao X, Fernández-Galiana Á, Barahona M, Stevens MM
August 2026 | Journal Article | Science advances | Read
Revisiting the Gold-Carbon Stretching Frequency: Spectroscopic and Computational Analysis of N-Heterocyclic Carbene Monolayers on Nanostructured Gold Surfaces
Albino M, Wojciechowski JP, Stevens MM
August 2026 | Journal Article | Nano letters | Read
Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection
Williams BG, Barrett JR, Scott JB, Rigby CA, Cagiada M, Quinkert D, McHugh K, Huhn A, Burnap SA, Gourjault C, Byrne F, Raghavan SSR, Rodrigues A, Bergamaschi L, Balzarotti B, Watson S, Miller N, King LDW, Donnellan FR, Gladstone CA, Paterson J, Scalabrino S, Silk SE, Salkeld J, Minassian AM, Skinner K, Struwe WB, Deane CM, Reece ST, Ward AB, Draper SJ
August 2026 | Journal Article (online ahead of print) | Immunity | Read
A Dural Extracellular Matrix Hydrogel with Neural Stem Cells Improves Recovery from Traumatic Brain Injury in Mice
Lee-Reeves C, Gregory HN, Gorup D, Chan M, Roche R, Irfan M, Penders J, Keane TJ, Ahmed AI, Phillips JB, Stevens MM
August 2026 | Journal Article | ACS biomaterials science & engineering | Read
α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.
Lam CL, Gatford NJF, Aragón-González A, Tanudjojo B, Sahoo A, Castle AR, Agarwal D, Jainarayanan A, Hester SS, Sen N, Benesch JLP, Fischer R, Sims D, Tofaris GK
August 2026 | Journal Article | Nature communications | Read
Intron retention in health and amyotrophic lateral sclerosis
Wang CY, Taylor S, Pandya VA, Clarke BE, Pal K, Shelkovnikova TA, Wang Y, Luisier R, Patani R
August 2026 | Journal Article (online ahead of print) |Brain: a journal of neurology | Read
Enhanced mGluR1 function causes motor deficits and region-specific Purkinje cell dysfunction
Ibrahim MF, Boyanova S, Cheng YC, Ligneul C, Bains RS, Johnpulle TC, Lerch JP, Mann EO, Oliver PL, Becker EBE
August 2026 | Journal Article | Brain: a journal of neurology | Read
M1-linked ubiquitination by LUBAC regulates AMPK signalling and the response to energetic stress
Elbæk CR, Gradinaru S, Dahlström AM, Frueh A, Jahan AS, Cuenco J, Aalto AL, Rizk J, Hawley SA, Franks SNJ, Stumpe M, Kolapalli SP, Wang CK, Ellison CJ, Hildebrandt X, Nielsen K, Priesmann D, Koch J, Deichmann M, Gullmets J, Verboom L, van Loo G, Peltzer N, Frankel LB, Elliott PR, Gyrd-Hansen M, Dengjel J, Ryan BJ, Hardie DG, Meinander A, Sakamoto K, Damgaard RB
August 2026 | Journal Article | Cell death and differentiation | Read
DNA-FLASH─a DNAzyme Walker-Based Nanosensor for Digital Biosensing at the Point of Care
Driesen S, Vloemans D, Velpula G, Leemput CV, Kümmerlin M, Kapanidis AN, Pinheiro C, Hendrix A, De Feyter S, Leirs K, Lammertyn J
August 2026 | Journal Article (online ahead of print)| ACS Nano | Read
BODIPY Photocage-Based Injectable Hydrogel for Light-Controlled Nanoparticle Release
Shao B, Peeler DJ, Fernandez Debets TFF, Wojciechowski JP, Shao Y, Cheng Y, Zhou K, Shattock RJ, Stevens MM
August 2026 | Journal Article | Small | Read
Interparticle interactions in nonlocal media: Attraction and repulsion from charge-polarization coupling
Behjatian A, Krishnan M.
August 2026 | Journal Article | Journal of Chemical Physics| Read
Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation
Diggines B, Fletcher M, Bibrowski M, Samnuan K, Chen R, Peeler DJ, Abouselo A, Hunter MR, Stevens MM, Brooks NJ, Elani Y
August 2026 | Journal Article (online ahead of print) | Advanced Materials | Read
GWAS of extended prescription analgesic use identifies genetic loci in chronic pain
Harlow CE, Uzochukwu E, Fernando HA, Mordaunt CE, Hughey JM, Eicher JD, Robinson L, Bowker N, Howe L, Liu J, Cortes A, Wilson P, Gungabissoon U, Benson VS, Nash A, Young G, Addis L, Xu CF, Webber C, Davitte J, Cader MZ.
August 2026 | Journal Article | Nat Communications | Read
Immunoglobulin binding protein (BiP) forms two types of dimers
New K, Lagos-Espinoza MIA, Casanova-Morales N, Asor R, Young JW, Alavi Z, Wilson CAM
August 2026 | Journal Article | Protein Science | Read
A Dural Extracellular Matrix Hydrogel with Neural Stem Cells Improves Recovery from Traumatic Brain Injury in Mice.
Lee-Reeves C, Gregory HN, Gorup D, Chan M, Roche R, Irfan M, Penders J, Keane TJ, Ahmed AI, Phillips JB, Stevens MM
July 2026 | Journal Article (online ahead of print) | ACS Biomaterials Science and Engineering | Read
Best practice mass photometry: a guide to optimal single-molecule mass measurement.
Kratochvíl J, van Wee R, Thiele JC, Loewenthal D, Bardzil J, Iqbal K, Benesch JLP, Thorpe S, Kukura P
July 2026 | Journal Article | Nature Protocols | Read
Multistage microrobots with pH-responsive release of platelet membrane-coated nanoparticles.
Sun R, Kim J, Leng Y, Zuo Y, Kim J, Xie R, Yang T, Ma L, Song X, Ma J, Joo J, Cho YK, Stevens MM.
July 2026 | Journal Article | Science Advances | Read
Experimental models of cerebral small vessel disease: Physiological constraints, translational challenges and future directions.
Beaumont S, Singh T, Soares LC, Salman MM
July 2026 | Journal Article | The Journal of Physiology | Read
Photobiomodulation restores blood-brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model.
Domocos M, Bragin DE, Shanbhag NC, Schlotterose L, Salman MM.
July 2026 | Journal Article | The Journal of Physiology | Read
Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for N-Acetylglucosaminyltransferase I.
Liu Y, Pieters S, Bineva-Todd G, Sagiroglugil M, Burnap SA, Hoddle F, Cioce A, Ohara A, Schmidt SD, Bruemmer K, Bertozzi CR, Polizzi K, Struwe WB, Rovira C, Schumann B
July 2026 | Journal Article | Journal of the American Chemical Society | Read
Varicose projection astrocytes: Conserved reactive cells in brain pathology.
Ciani C, Pistorio G, Giancola S, Mearelli M, Mongelli FE, Forouzeh D, Campos Soares L, Gonzalez Martin M, Lichtenstein ME, Mio L, Christou E, Hastings K, Nguyen Do AQ, Ramos-Gonzalez P, Matute C, Kuliesiute U, Dötterer SE, Luksys G, Rocka S, Neniskyte U, Anthony DC, Ayub M, Centelleghe C, Arevalo MA, Graïc JM, Petrelli F, Verkhratsky A, Iraci N, Cavaliere F, Muñoz-Ballester C, Salman MM, Ulloa Severino FP, Falcone C
July 2026 | Journal Article | Science Advances | Read
Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection
Kirtley P, Martinson T, Donnellan FR, Aleshnick M, Nielsen K, Mayer BT, Borate B, Huang TJ, Pipini D, Rigby CA, Quinkert D, Silk SE, Minassian AM, McHugh K, Draper SJ, Wilder BK
June 2026 | Journal Article (online ahead of print) | Cell Reports | Read
Multi-spin control from one-spin pulses
Lim S, Guo B, Turner AL, Buchanan C, Baldwin AJ, Jones JA
June 2026 | Journal Article (online ahead of print) | Journal of Magnetic Resonance | Read
Deletion of Snap25 disrupts glial remodeling in aging mouse brain
Vadisiute A, Szabo F, Luchanskaya S, Drevenakova V, Messore F, Ugwudike A, Greene G, Mueller M, Morse SV, Hoerder-Suabedissen A, Molnár Z
June 2026 | Journal Article | iScience | Read
Labelling in cryogenic electron tomography - Bridging the gap between correlative light and electron microscopy and protein identification
Machala EA, Baker LA
June 2026 | Journal Article | Current Opinion in Structural Biology | Read
Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection
Williams BG, Barrett JR, Scott JB, Rigby CA, Cagiada M, Quinkert D, McHugh K, Huhn A, Burnap SA, Gourjault C, Byrne F, Raghavan SSR, Rodrigues A, Bergamaschi L, Balzarotti B, Watson S, Miller N, King LDW, Donnellan FR, Gladstone CA, Paterson J, Scalabrino S, Silk SE, Salkeld J, Minassian AM, Skinner K, Struwe WB, Deane CM, Reece ST, Ward AB, Draper SJ
June 2026 | Journal Article (online ahead of print) | Immunity | Read
From statistics to deep learning in single-molecule fluorescence resonance energy transfer analysis
Beigzadeh M, Hazra JP, Kapanidis AN
June 2026 | Journal Article (online) | Current Opinion in Structural Biology | Read
Harnessing prophylactic vaccines for targeted cancer immunotherapy by phage-guided delivery of cognate antigens to tumors
Waramit S, Suwan K, Küçük A, Benjathummarak S, Cencioni MT, Ashfield R, Gay L, Draper SJ, Hajitou A
Beigzadeh M, Hazra JP, Kapanidis AN
June 2026 | Journal Article (online) | Biomaterials | Read
A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum
Abdelwahed A, Eskildsen CE, Panariello L, Shamsabadi A, Sadler CJ, Wilkes EH, Galvanin F, Cheng Y, Carvalho S, Saso S, Stevens MM
June 2026 | Journal Article (online) | Advanced Science | Read
Experimental models of cerebral small vessel disease: Physiological constraints, translational challenges and future directions
Beaumont S, Singh T, Soares LC, Salman MM
June 2026 | Journal Article (online ahead of print) | The Journal of Physiology | Read
Native mass spectrometry reveals DltA catalysis, DltC loading, and inhibition in the d-alanylation pathway
Wang Y, Squires H, Addo MA, Gerdt JP, El-Baba TJ, MacLean RC, Robinson CV, Bolla JR
June 2026 | Journal Article (online) | RSC Advances | Read
The Motor Neuron Disease Register for England, Wales, and Northern Ireland: Protocol for a Population Register
Biondi, A, Gray, E, Aggreh, M, Jones, E, Collingwood, A, Knox, L, Bredin, A, Setters, D, Talbot, K, & Al-Chalabi, A
June 2026 | Journal Article (online) | JMIR Research Protocols | Read
GWAS of extended prescription analgesic use identifies genetic loci in chronic pain
Harlow CE, Uzochukwu E, Fernando HA, Mordaunt CE, Hughey JM, Eicher JD, Robinson L, Bowker N, Howe L, Liu J, Cortes A, Wilson P, Gungabissoon U, Benson VS, Nash A, Young G, Addis L, Xu CF, Webber C, Davitte J, Cader MZ
May 2026 | Journal Article (online ahead of print) | Nature Communications | Read
Rational discovery of therapeutic PAK1 allosteric activators.
He Y, Bae JSH, Nowak E, Outeiral C, Nissley DA, Tumber A, Berridge G, Salah E, Wang Y, He W, Zhang H, Chen T, Tusk S, Mathea S, Wang YJ, Grassam-Rowe A, Kukura P, Schofield CJ, O'Brien DP, Pierangelini A, Churchill GC, Lanyon-Hogg T, Ke Y, Xu C, Ye T, Watkins H, Ying L, Koschinski A, Solaro RJ, Tan X, Bolla JR, Wang X, Knapp S, Deane CM, Zaccolo M, Nowotny M, Lei M
May 2026 | Journal Article (online) | Cell | Read
Labelling in cryogenic electron tomography - Bridging the gap between correlative light and electron microscopy and protein identification
Machala EA, Baker LA
June 2026 | Journal Article | Current Opinion in Structural Biology | Read
Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection
Williams BG, Barrett JR, Scott JB, Rigby CA, Cagiada M, Quinkert D, McHugh K, Huhn A, Burnap SA, Gourjault C, Byrne F, Raghavan SSR, Rodrigues A, Bergamaschi L, Balzarotti B, Watson S, Miller N, King LDW, Donnellan FR, Gladstone CA, Paterson J, Scalabrino S, Silk SE, Salkeld J, Minassian AM, Skinner K, Struwe WB, Deane CM, Reece ST, Ward AB, Draper SJ
June 2026 | Journal Article (online ahead of print) | Immunity | Read
From statistics to deep learning in single-molecule fluorescence resonance energy transfer analysis
Beigzadeh M, Hazra JP, Kapanidis AN
June 2026 | Journal Article (online) | Current Opinion in Structural Biology | Read
Harnessing prophylactic vaccines for targeted cancer immunotherapy by phage-guided delivery of cognate antigens to tumors
Waramit S, Suwan K, Küçük A, Benjathummarak S, Cencioni MT, Ashfield R, Gay L, Draper SJ, Hajitou A
Beigzadeh M, Hazra JP, Kapanidis AN
June 2026 | Journal Article (online) | Biomaterials | Read
A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum
Abdelwahed A, Eskildsen CE, Panariello L, Shamsabadi A, Sadler CJ, Wilkes EH, Galvanin F, Cheng Y, Carvalho S, Saso S, Stevens MM
June 2026 | Journal Article (online) | Advanced Science | Read
Experimental models of cerebral small vessel disease: Physiological constraints, translational challenges and future directions
Beaumont S, Singh T, Soares LC, Salman MM
June 2026 | Journal Article (online ahead of print) | The Journal of Physiology | Read
Native mass spectrometry reveals DltA catalysis, DltC loading, and inhibition in the d-alanylation pathway
Wang Y, Squires H, Addo MA, Gerdt JP, El-Baba TJ, MacLean RC, Robinson CV, Bolla JR
June 2026 | Journal Article (online) | RSC Advances | Read
The Motor Neuron Disease Register for England, Wales, and Northern Ireland: Protocol for a Population Register
Biondi, A, Gray, E, Aggreh, M, Jones, E, Collingwood, A, Knox, L, Bredin, A, Setters, D, Talbot, K, & Al-Chalabi, A
June 2026 | Journal Article (online) | JMIR Research Protocols | Read
GWAS of extended prescription analgesic use identifies genetic loci in chronic pain
Harlow CE, Uzochukwu E, Fernando HA, Mordaunt CE, Hughey JM, Eicher JD, Robinson L, Bowker N, Howe L, Liu J, Cortes A, Wilson P, Gungabissoon U, Benson VS, Nash A, Young G, Addis L, Xu CF, Webber C, Davitte J, Cader MZ
May 2026 | Journal Article (online ahead of print) | Nature Communications | Read
Rational discovery of therapeutic PAK1 allosteric activators.
He Y, Bae JSH, Nowak E, Outeiral C, Nissley DA, Tumber A, Berridge G, Salah E, Wang Y, He W, Zhang H, Chen T, Tusk S, Mathea S, Wang YJ, Grassam-Rowe A, Kukura P, Schofield CJ, O'Brien DP, Pierangelini A, Churchill GC, Lanyon-Hogg T, Ke Y, Xu C, Ye T, Watkins H, Ying L, Koschinski A, Solaro RJ, Tan X, Bolla JR, Wang X, Knapp S, Deane CM, Zaccolo M, Nowotny M, Lei M
May 2026 | Journal Article (online) | Cell | Read
Labelling in cryogenic electron tomography - Bridging the gap between correlative light and electron microscopy and protein identification.
Machala EA, Baker LA
May 2026 | Journal Article (online ahead of print) | Current Opinion in Structural Biology | Read
Dynamics of an RNase H-Responsive Tetrahedral DNA Nanostructure for Efficient Intracellular microRNA Inhibition
Martins ASG, Reis SD, Baboi R, Furlan F, Cortinhas J, Carvalho FA, Santos NC, Bath J, Benson E, Pêgo AP, Moreno PMD
May 2026 | Journal Article (online) | Bioconjugate Chemistry | Read
Cell surface localisation of GPI-anchored receptors in Trypanosoma brucei
Banerjee S, Minshall N, Cook AD, Macleod O, Webb H, Higgins MK, Carrington M
May 2026 | Journal Article (online) | eLife | Read
Teneurin-3 and latrophilin-2 are required for somatotopic map development and somatosensory topognosis
Sangster KT, Zhang X, Del Toro D, Sarantopoulos C, Moses AM, Mahasenan S, Pederick DT, Perreault S, Fallet-Bianco C, Roome RB, Seiradake E, Luo L, Kania A
May 2026 | Journal Article (online) | Current Biology | Read
Structural basis for hemoglobin scavenging by CD163 reveals mechanism of ligand promiscuity
Zhou RX, Higgins M
May 2026 | Journal Article (online) | PLoS Biology | Read
Bionano Interface Optimization for Rational Lateral Flow Assay Development
Sadler CJ, Miller M, Darmawan KK, Sandler JP, Ng HC, Shamsabadi A, Creamer A, Robinson CV, Yarovsky I, Stevens MM
May 2026 | Journal Article (online) | ACS Nano| Read
SPRY domains encode ubiquitin ligase specificity for ZAP and RIG-I
Syed I, Chen S, Peeler DJ, McKay PF, Briones-Orta MA, Bohn JA, Shattock RJ, Gonçalves-Carneiro D
May 2026 | Journal Article (online) | PLoS Pathogens | Read
Harnessing prophylactic vaccines for targeted cancer immunotherapy by phage-guided delivery of cognate antigens to tumors
Waramit S, Suwan K, Küçük A, Benjathummarak S, Cencioni MT, Ashfield R, Gay L, Draper SJ, Hajitou A
May 2026 | Journal Article (online) |Biomaterials | Read
A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies
Donnellan FR, Rayaprolu V, Rijal P, O'Dowd V, Parvate A, Callaway H, Hariharan C, Parekh D, Hui S, Shaffer KCL, Avalos RD, Hastie KM, Schimanski L, Müller-Kräuter H, Strecker T, Balaram A, Halfmann P, Saphire EO, Lightwood DJ, Townsend AR, Draper SJ
May 2026 | Journal Article (online ahead of print) | Npj Viruses | Read
A posttranslational proteomic survey of a single anatomically preserved human 20-week postconception brain
Bandiera S, Bogetofte H, Jensen P, Hussain R, Nischal SA, Rihova L, Clowry GJ, Larsen MR, Molnár Z, Carlyle BC
May 2026 | Journal Article (online ahead of print) | Journal of Anatomy | Read
Structural basis for transport and inhibition of nucleotide sugar transport in pathogenic fungi
Parker JL, Deme JC, Feddersen B, Lea SM, Newstead S
May 2026 | Journal Article (online ahead of print) | Nature Communations | Read
Adhesion G protein-coupled receptors
Langenhan T, Anderson GR, Araç D, Aust G, Avila-Zozaya M, Bagger SM, Barth P, Berndt S, Blacklow SC, Blanco-Redondo B, Boucard AA, Bridges JP, Brodmerkel LS, Caron KM, Chung YK, Dates AN, de Araujo Farias V, Del Toro D, Duman JG, Engel FB, Favara DM, Formstone CJ, Fu C, Garcia De Las Bayonas A, Georgiadi A, Gloriam DE, Hall RA, Hamann J, Hildebrand PW, Hsiao CC, Huang BX, Javitch JA, Kim HY, Kittel RJ, Kleinau G, Leduc R, Liebscher I, Lin HH, Linnert J, Ludwig MG, Martinelli DC, Mathiasen S, Matúš D, Melkumyan M, Moreno-Salinas AL, Mulder J, Nash MA, Pal K, Pederick DT, Perry-Hauser NA, Piao X, Ping YQ, Placantonakis DG, Pohl F, Prömel S, Rosenkilde MM, Sabbagh L, Sando RC, Scheerer P, Schöneberg T, Seiradake E, Selcho M, Seufert F, Singh AK, Skiniotis G, Spiess K, Sträter N, Strutt D, Südhof TC, Sun J, Tall GG, Thor D, Tilley DG, Tolias KF, Vallon M, Van Meir EG, Vanhollebeke B, Wiggin GR, Wolfrum U, Yan J, Zaidman NA, Zou Y, Scholz N
May 2026 | Journal Article | Pharmacological Reviews | Read
Variant-to-function dissection of the 17q21.31 locus resolves ANKRD1 as a convergent regulatory target
Olaoye OJ, Farrow SL, Cooper AA, Nyaga DM, O'Sullivan JM
April 2026 | Journal Article (online ahead of print) | BMC Med Genomics | Read
Structural basis for phosphorylation and allosteric regulation of bacterial glycogen phosphorylase by histidine phosphocarrier protein
Di Domenico V, Franceus J, Mastrella L, De Beul E, Alcaide-Jiménez A, Paredes-Martínez F, Villegas-Ruiz JC, Holden E, Rey AD, D'Angelo C, Cifuente JO, Struwe WB, Biondi RM, Marina A, Connell SR, Benesch JLP, Casino P, Colleoni C, Desmet T, Guerin ME
April 2026 | Journal Article (online ahead of print) | Nature Communications | Read
Dynamics of an RNase H-Responsive Tetrahedral DNA Nanostructure for Efficient Intracellular microRNA Inhibition
Martins ASG, Reis SD, Baboi R, Furlan F, Cortinhas J, Carvalho FA, Santos NC, Bath J, Benson E, Pêgo AP, Moreno PMD
April 2026 | Journal Article (online ahead of print) | Bioconjugate Chemistry | Read
Bifunctional Lipid-Protein Cross-linking Efficiency and Reaction Products
Kirschbaum C, Lennartz HM, Cook KC, Böhlig K, Papangelis A, Robinson CV, Nadler AJ
April 2026 | Journal Article (online) | Journal of the American Chemical Society | Read
The schizophrenia associated protein DISC1 forms a multivalent tetrameric hub via conserved UVR dimers
Zhou JC, Kratochvil J, Ye F, El Omari K, Kukura P, Zhang M, Seiradake E
April 2026 | Journal Article (online ahead of print) | Nature Communications | Read
Epigenetic biomarkers in neurodegenerative diseases: from molecular signatures to therapeutic targets
Washer SJ, Frith M, Cowan E, Dempster E, Mill J, Farrow SL
April 2026 | Journal Article (online ahead of print) | Trends in Neurosciences | Read
Structurally exclusive Teneurin complexes orchestrate divergent programs in early cortical development
Berbeira-Santana M, Peregrina C, Okuda K, Zhou JC, Carrasquero-Ordaz M, Roberts AV, Thomas AE, Haanappel E, Chavent M, El Omari K, Baker LA, Pederick DT, Pardon E, Steyaert J, Nägerl UV, Del Toro D, Seiradake E
April 2026 | Journal Article (online ahead of print) | Nature Communications | Read
DeepTRACE brings flexible machine learning to single-molecule track analysis
Pambos OJ, Wright JAR, Kapanidis AN
April 2026 | Journal Article (online ahead of print) | Communications Biology | Read
Photobiomodulation restores blood-brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model
Domocos M, Bragin DE, Shanbhag NC, Schlotterose L, Salman MM
April 2026 | Journal Article (online ahead of print) | The Journal of Physiology | Read
Organizing across disciplines to tackle shared computational challenges
Treyde W, Kwiatkowski A, Achterberg J, Akarca D, Buttenschoen M, Byrne RT, Didi K, Kordova K, Lála J, Langford J, Mroz AM, Radmard P, Szczypiński FT, Sevenster E, Van den Bossche I, Wójcik M
April 2026 | Journal Article (online) | Patterns (NY) | Read
From statistics to deep learning in single-molecule fluorescence resonance energy transfer analysis
Beigzadeh M, Hazra JP, Kapanidis AN
April 2026 | Journal Article (online ahead of print) | Current Opinion in Structural Biology | Read
A temporal dialogue between the circadian clock and chronic inflammatory diseases
Chen S, Ray D
April 2026 | Journal Article (online) | Disease Models & Mechanisms | Read
A guide to using embedded ethics in human stem-cell-based embryo model research
Bentzen HB, Gaillard M, Nachman I, Reumann D, Gadegaard N, David L, Lanner F, Moris N, Pasque V, Rivron N, Sozen B, Isasi R, Krauss S, Veenvliet JV
April 2026 | Journal Article (online) | Nature Cell Biology | Read
Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles
Karabova MK, Del Ser-Badia A, Hedegaard A, Washer SJ, Baykam Z, O'Brien DP, Vendrell I, Hester SS, Fischer R, Johnson E, Melia CE, Matthews-Palmer TRS, Matadeen R, Santambrogio A, Metrick MA 2nd, Vendruscolo M, Keeling S, Cheam KAX, McEwan WA, Kosik KS, Day TA, James WS, Cowley SA
April 2026 | Journal Article (online) | Alzheimer's & Dementia | Read
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Cruz EM, Soares LC, Greene G, Messore F, Abuelem M, Li M, Andersen C, Domocos M, Vitiello E, Razak RA, Lawston M, Moser G, Vasaturo-Kolodner T, Barkat M, Bill RM, Mann E, Zhou L, Salman MM, Bayley H, Molnár Z, Szele FG
April 2026 | Journal Article (online) | Advanced Science | Read
Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease
Jouen-Tachoire TRH, Proks P, Seiferth D, Crowther K, Biggin PC, Baukrowitz T, Schewe M, Tucker SJ
April 2026 | Journal Article (online) | EMBO | Read
An Evolutionary Distinct Nipah Virus N-Glycosylation Site Provides Stability for Receptor Engagement
Hawkins TÉ, Calvaresi V, Burnap SA, Demyanenko Y, Wu L, Struwe WB
April 2026 | Journal Article (online) | Molecular & Cellular Proteomics | Read
Integrative Proteomic and Lipidomic Analysis of Patients With Acute Myocardial Infarction Treated With PCSK9 Antibodies and Statins
Schmidt LE, Burnap SA, Singh B, Takov K, Losdat S, Schrutka L, Galli L, Theofilatos K, Otto GW, Hengstenberg C, Tzoulaki I, Lang IM, Koskinas KC, Speidl WS, Räber L, Mayr M
April 2026 | Journal Article (online) | Circulation: Genomic and Precision Medicine | Read
Hydrogels Incorporating Donor-Acceptor Stenhouse Adducts as a Platform for Photoinduced, On-Off Switchable Release of Small Molecule Cargos
Dell TN, Cammack-Najera A, Tresa R, Matubbar F, Kaya B, Lathan U, Chami M, DiNardi RG, Rifaie-Graham O, Wojciechowski JP, Stevens MM
April 2026 | Research Article (online) | Macromolecular Rapid Communications | Read
Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder
Yan S, Sahoo A, Zerenner T, Marek K, Sommerauer M, Oertel W, Hu MT, Tofaris GK
April 2026 | Journal Article (online) | Annals of Neurology | Read
Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines
Arman BY, Magri A, Barbaglia MN, Petherbridge L, Brook J, Bharucha T, Legge I, Walsby-Tickle J, Deats M, Banerjee S, Mosca S, Jena R, Ranade DS, Chunekar SR, Patil KD, Gairola S, Merchant HA, Stokes R, Kuwana R, Maes A, James T, Green C, McCullagh J, Matousek P, Caillet C, Newton PN, Zitzmann N, Gangadharan B
March 2026 | Journal Article (online) | International Journal of Pharmaceutics | Read
Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder
Yan S, Sahoo A, Zerenner T, Marek K, Sommerauer M, Oertel W, Hu MT, Tofaris GK
March 2026 | Journal Article (online) | Annals of Neurology | Read
The Impact of Polyethylene Glycol Lipid Anchors on the Physicochemical Properties, Protein Corona, Function, and Biodistribution of Lipid Nanoparticles
Lu CE, Liu K, Gallud A, Meklesh V, Ravnkilde LT, Santos J, Dias Louro F, Miliotis T, Alfonzo-Mendez MA, Rejman J, Panariello L, Barriga HMG, Stevens MM, Höök F, Yanez Arteta M, Ulander J, Jones S, Sabirsh A
March 2026 | Journal Article (online) | ACS Nano | Read
Structural basis for pH-responsive amino acid transport via SLC7A4
Kolokouris D, Bothra A, Kato T, Zeng YC, Lichtinger S, Parker JL, Biggin PC, Newstead S
March 2026 | Journal Article (online) | Nature Communications | Read
Image-guided optimization of regenerative graft attachment to the heart
Feng Z, Hachim D, Mylonaki I, Colzani M, Bettini A, Dondi C, Obregon-Gomez I, Lin J, Gambardella L, Bayraktar S, Deniszczyc E, Pope C, Saccoh AF, Ahmed E, Lythgoe MF, Kalber TL, Patrick PS, Sinha S, Stevens MM, Stuckey DJ
March 2026 | Journal Article (online) | Biomaterials | Read
Nanoparticle-Mediated Interface Engineering for Uniform, Reproducible Electron Transport Layers in Scalable Perovskite Solar Cells
Henderson C, Marques AS, Bicalho IS, Hart LJF, Monahan A, Stewart K, Asano K, Lan T, Vacha M, Stevens MM, Barnes PRF, Bagnis D, Kim JS
March 2026 | Journal Article (online) | ACS applied materials & interfaces | Read
Quantitative Mapping of NHS Ester-Protein Reactivity Using Native Top-Down Mass Spectrometry
Bennett JL, Ramsay OB, Lutomski CA, Kirschbaum C, Robinson CV
March 2026 | Journal Article (online) | Journal of the American Society for Mass Spectrometry | Read
B and T cell responses to pre-erythrocytic R21/Matrix-M and blood-stage RH5.1/Matrix-M malaria vaccines in endemic settings
Bundi CK, Muñoz O, Kibwana E, Bellamy D, Stockdale L, Barrett JR, McHugh K, Mtaka I, Kalinga W, Kimani D, Nyamako L, Keter K, Ogwang R, Hill AVS, Bejon P, Hamaluba M, Silk SE, Minassian AM, Draper SJ, Olotu AI, Kapulu MC, Ewer KJ, Nielsen CM
March 2026 | Journal Article (online) | Frontiers in Immunology | Read
Harnessing Phase Separation for the Development of High-Performance Hydrogels
Shao Y, Ma Y, Shao B, Stevens MM
March 2026 | Journal Article (online) | Advanced Science | Read
Towards intelligent and miniaturized drug delivery devices
Wei X, Buse JB, Chen H, Desai TA, Stevens MM, Traverso G, Langer R, Gu Z
March 2026 | Journal Article (online) | Nature | Read
Structure-guided design of a PfCyRPA-based vaccine against blood-stage malaria
Alam N, Wolfle C, Butkeviciute E, Quinkert D, King LDW, Higgins MK
March 2026 | Journal Article (online) | EMBO Molecular Medicine | Read
CHCHD2 links mitochondrial dysfunction and α-synuclein misfolding in Parkinson's disease
Narendra D, Ryan BJ
March 2026 | Journal Article (online) | Trends in Neurosciences | Read
Structures of proteinase 3 and the CD177 receptor complex reveal a major autoantibody epitope
Zheng-Gérard C, Joha J, Carrasquero M, El Omari K, Lowe E, Dubey S, Draper SJ, Chang YC, Lin HH, Salama AD, McHugh K, Seiradake E
March 2026 | Journal Article (online) | EMBO Reports | Read
Compartment-specific correlation of pathological α-synuclein in prodromal Parkinson's disease
Röttgen S, Sommerauer M, Yan S, Hungerland C, Fink GR, Ophey A, Barbe MT, Müller L, Tamgüney G, Tofaris GK
March 2026 | Journal Article (online) | Parkinsonism & Related Disorders | Read
Nanoparticle-Mediated Interface Engineering for Uniform, Reproducible Electron Transport Layers in Scalable Perovskite Solar Cells
Henderson C, Marques AS, Bicalho IS, Hart LJF, Monahan A, Stewart K, Asano K, Lan T, Vacha M, Stevens MM, Barnes PRF, Bagnis D, Kim JS
March 2026 | Journal Article (online) | ACS Applied Materials & Interfaces | Read
CHCHD2 links mitochondrial dysfunction and α-synuclein misfolding in Parkinson's disease
Narendra D, Ryan BJ
March 2026 | Journal Article (online) | Trends in Neuroscience | Read
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Cruz EM, Soares LC, Greene G, Messore F, Abuelem M, Li M, Andersen C, Domocos M, Vitiello E, Razak RA, Lawston M, Moser G, Vasaturo-Kolodner T, Barkat M, Bill RM, Mann E, Zhou L, Salman MM, Bayley H, Molnár Z, Szele FG
February 2026 | Journal Article (online) | Advanced Science | Read
Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease
Jouen-Tachoire TRH, Proks P, Seiferth D, Crowther K, Biggin PC, Baukrowitz T, Schewe M, Tucker SJ
February 2026 | Journal Article (online) | The EMBO Journal | Read
A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum
Abdelwahed A, Eskildsen CE, Panariello L, Shamsabadi A, Sadler CJ, Wilkes EH, Galvanin F, Cheng Y, Carvalho S, Saso S, Stevens MM
February 2026 | Journal Article (online) | Advanced Science | Read
Structural basis for carbohydrate recognition by the Gal/GalNAc lectin of Entamoeba histolytica involved in host cell adhesion
Gérard SF, Redfield C, Higgins MK
February 2026 | Journal Article (online) | PLoS Pathogens | Read
Direct measurement of the attractive electrosolvation force between a pair of colloidal particles
Wang S, Le A, Walker-Gibbons R, Krishnan M.
February 2026 | Journal Article (online) | Reports on Progress in Physics | Read
An Evolutionary Distinct Nipah Virus N-Glycosylation Site Provides Stability for Receptor Engagement
Hawkins TE, Calvaresi V, Burnap SA, Demyanenko Y, Wu L, Struwe WB
February 2026 | Journal Article (online) | Molecular & Cellular Proteomics | Read
Structures of proteinase 3 and the CD177 receptor complex reveal a major autoantibody epitope
Zheng-Gérard C, Joha J, Carrasquero M, El Omari K, Lowe E, Dubey S, Draper SJ, Chang YC, Lin HH, Salama AD, McHugh K, Seiradake E
February 2026 | Journal Article (online) | EMBO Reports | Read
Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin
Brook J, Bharucha T, Arman BY, Caillet C, Morris S, Taylor-Siddons M, Fernandez LG, Walsby-Tickle J, Legge I, Banerjee S, Deats M, Jena R, Ranade DS, Chunekar SR, Patil KD, Gairola S, Dunachie S, Merchant HA, Stokes R, Kuwana R, Maes A, Gilbert S, McCullagh J, Matousek P, Zitzmann N, Newton PN, Gangadharan B, James T
February 2026 | Journal Article (online)| Scientific Reports | Read
Ancestral neuronal receptors are bacterial accessory toxins
Raoelijaona F, Szczepaniak J, Schahl A, Bray JE, Zhou JC, Baker L, El Omari K, Lowe E, Low YS, Rodriguez CM, Landsberg MJ, Lott JS, Kleanthous C, Chavent M, Maiden MC, Seiradake E
February 2026 | Journal Article (online) | Nature Communications | Read
M1-linked ubiquitination by LUBAC regulates AMPK signalling and the response to energetic stress
Elbæk CR, Gradinaru S, Dahlström AM, Frueh A, Jahan AS, Cuenco J, Aalto AL, Rizk J, Hawley SA, Franks SNJ, Stumpe M, Kolapalli SP, Wang CK, Ellison CJ, Hildebrandt X, Nielsen K, Priesmann D, Koch J, Deichmann M, Gullmets J, Verboom L, van Loo G, Peltzer N, Frankel LB, Elliott PR, Gyrd-Hansen M, Dengjel J, Ryan BJ, Hardie DG, Meinander A, Sakamoto K, Damgaard RB
February 2026 | Journal Article (online) | Cell Death and Differentiation | Read
Integrative Proteomic and Lipidomic Analysis of Post-Myocardial Infarction Patients Treated With PCSK9 Antibodies and Statins
Schmidt LE, Burnap SA, Singh B, Takov K, Losdat S, Schrutka L, Galli L, Theofilatos K, Otto GW, Hengstenberg C, Tzoulaki I, Lang IM, Koskinas KC, Speidl WS, Räber L, Mayr M
February 2026 | Journal Article (online) | Circulation: Genomic and Precision Medicine | Read
Polyanion Chemistry Engineers Ternary RNA Nanoparticle Structure/Function from the Inside-Out
Hu L, Peeler DJ, Jin T, Doutch JJ, Shao B, Yeow J, Ma L, Barriga HMG, Tang J, Cao X, Liu C, Grigsby CL, Alexander-Katz A, Shattock RJ, Stevens MM
February 2026 | Journal Article (online) | ACS Nano | Read
Working against the clock: does night shift work drive multisystem disease?
Richmond RC, Ray DW
February 2026 | Journal Article (online) | European Journal of Preventive Cardiology | Read
Biological data governance in an age of AI
Bloomfield D, Black JRM, Crook O, Brandes N, Hanke MS, Inglesby TV, Cicero A, Pollack R, Hernandez-Boussard T, Imperiale MJ, Altman RB, Pannu J
February 2026 | Journal Article (online) | Science | Read
Deep Learning-Based Event Classification of Mass Photometry Data for Optimal Mass Measurement at the Single-Molecule Level
Iqbal K, Thiele JC, Saman D, Peters JS, Thorpe S, Tusk S, Bardzil J, Benesch JLP, Kukura P
February 2026 | Journal Article (online) | ACS Nano | Read
Glucocorticoid-dependence and independence of the circadian liver transcriptome
Maidstone RJ, Hunter AL, Iqbal M, Begley N, Baxter M, Loudon ASI, Rattray M, Ray DW
February 2026 | Journal Article (online) | NPJ Biological Timing and Sleep | Read
Mechanism for a molecular assembler of sequence- controlled polymers using parallel DNA and a DNA polymerase
Bath J, Turberfield AJ
February 2026 | Journal Article (online) | Nanoscale Horizons | Read
Circadian and sleep medicine: challenges and future directions for metabolic and endocrine research
Marjot T, Yang N, Ray DW
February 2026 | Journal Article (online) | The Lancet: Diabetes and Endocrinology | Read
Ultrasound-Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units
Brans VA, Constantinou AP, Kibble MJ, Nele V, Reumann D, Bau L, Callens SJP, Armstrong JPK, Newell N, Coussios CC, Stevens MM, Gray MD
February 2026 | Journal Article (online) | Advanced Healthcare Materials | Read
Update and New Implementation of the MIRAGE Reporting Guidelines for Mass Spectrometry Experiments in Glycoscience
Lisacek F, Hackett WE, Thaysen-Andersen M, Karlsson NG, Klein J, Kolarich D, Maciej-Hulme ML, Okuda S, Packer NH, Struwe WB, Takahashi Y, Tiemeyer M, Zaia J, Aoki-Kinoshita KF, Kettner C
February 2026 | Journal Article (online) | Molecular & Cellular Proteomics | Read
Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines
Alam N, Farrell B, Jamwal A, Higgins MK
February 2026 | Journal Article (online) | Nature Reviews: Microbiology | Read
Measuring glymphatic function: Assessing the toolkit
Ayyappan K, Unger L, Kitchen P, Bill RM, Salman MM
February 2026 | Journal Article (online) | Neural Regeneration Research | Read
Vigilance state dissociation induced by 5-MeO-DMT in mice
Bréant BJB, Prius Mengual J, Andrews A, Hoerder-Suabedissen A, Patel J, Bannerman DM, Sharp T, Vyazovskiy VV
January 2026 | Journal Article (online) | Communications Biology | Read
Microglia in C9orf72-associated amyotrophic lateral sclerosis: More or less active?
Vahsen BF, Pasterkamp RJ
January 2026 | Journal Article (online) | Neural Regeneration Research | Read
Compartment-specific correlation of pathological α-synuclein in prodromal Parkinson's disease
Röttgen S, Sommerauer M, Yan S, Hungerland C, Fink GR, Ophey A, Barbe MT, Müller L, Tamgüney G, Tofaris GK
January 2026 | Journal Article (online) | Parkinsonism & Related Disorders | Read
Enhanced mGluR1 function causes motor deficits and region-specific Purkinje cell dysfunction
Ibrahim MF, Boyanova S, Cheng YC, Ligneul C, Bains RS, Johnpulle TC, Lerch JP, Mann EO, Oliver PL, Becker EBE
January 2026 | Journal Article (online) | Brain | Read
Deep Learning-Based Event Classification of Mass Photometry Data for Optimal Mass Measurement at the Single-Molecule Level
Iqbal K, Thiele JC, Saman D, Peters JS, Thorpe S, Tusk S, Bardzil J, Benesch JLP, Kukura P
January 2026 | Journal Article (online) | ACS Nano | Read
Simulated natural daylight and twilight modulate activity and light sampling behaviour in mice
Steel LCE, Hankins MW, Foster RG, Peirson SN
January 2026 | Journal Article (online) | BMC Biology | Read
Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels
Bied M, Landra-Willm A, Chassot AA, Mendez-Otalvaro EF, Sueur B, Roßmann K, de la Peña E, Fossat P, Tucker SJ, Noël J, Kopec W, Viana F, Broichhagen J, Boué-Grabot E, Sandoz G
January 2026 | Journal Article (online) | Nature Communications | Read
Polyanion Chemistry Engineers Ternary RNA Nanoparticle Structure/Function from the Inside-Out
Hu L, Peeler DJ, Jin T, Doutch JJ, Shao B, Yeow J, Ma L, Barriga HMG, Tang J, Cao X, Liu C, Grigsby CL, Alexander-Katz A, Shattock RJ, Stevens MM
January 2026 | Journal Article (online) | ACS Nano | Read
Synthetic nanoparticles for cell-type specific, spatially resolved loading and export of MiRNAs in neural cells
Mignanelli M, Siano G, Iannone V, Scarlatti A, Orsini E, Maggi L, Rizzo M, Caiazza MC, Wade-Martins R, Salvetti A, Ghiloni G, Cremisi F, Casieri V, Fruzzetti L, Novelli E, Ataman A, Cattaneo A, Di Primio C
January 2026 | Journal Article (online) | Journal of Nanobiotechnology | Read
Quantitative Mapping of NHS Ester-Protein Reactivity Using Native Top-Down Mass Spectrometry
Bennett JL, Ramsay OB, Lutomski CA, Kirschbaum C, Robinson CV
January 2026 | Journal Article (online) | Journal of the American Society for Mass Spectrometry | Read
From sequence to function: Bridging single-molecule kinetics and molecular diversity
Kapanidis AN, Muras L, Sreenivasa K, Hazra JP, van Noort J, Joo C, Deindl S
January 2026 | Journal Article (online) | Science | Read
Generating cerebellar organoids from pluripotent stem cells
Becker EBE, Mayer S, Kutscher LM
January 2026 | Journal Article (online) | Diseases Models & Mechanisms | Read
Hydrogels Incorporating Donor-Acceptor Stenhouse Adducts as a Platform for Photoinduced, On-Off Switchable Release of Small Molecule Cargos
Dell TN, Cammack-Najera A, Tresa R, Matubbar F, Kaya B, Lathan U, Chami M, DiNardi RG, Rifaie-Graham O, Wojciechowski JP, Stevens MM
January 2026 | Journal Article (online) | Macromolecular Rapid Communications | Read
Molecular tags for electron cryo-tomography
Silvester E, Baker LA
December 2025 | Journal Article | Emerging Topics in Life Sciences | Read
Preclinical Models for Schizophrenia and Sleep Oscillations: From Biomarkers to Mechanisms
Vyazovskiy VV, Bannerman DM
December 2025 | Journal Article | Biological Psychiatry | Read
Designing Physical Unclonable Functions From Optically Active Materials
Klausen M, Zhang J, Stevens MM
December 2025 | Journal Article | Advanced Materials | Read
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Han M, Lin W, Cao Y, Murray P, Wilm B, McWilliam SJ, Curran J, Xie R
December 2025 | Journal Article | Advanced Healthcare Materials | Read
N-terminal half of MED14 is critical for Mediator-RNA polymerase II interaction and the resulting transcription
Baris Y, Jabbar J, Yozgat Y, Dinccelik-Aslan M, Cigirgan E, Erden M, Bay S, Aslan V, Cevher MA
December 2025 | Journal Article | Journal of Biological Chemistry | Read
Smart Healthcare Photonic Nanomaterials and Devices
Stevens MM, Rogers JA, Hahn SK
December 2025 | Journal Article| Advanced Materials | Read
Hybrid Detergents Facilitate Scalable Charge Reduction and Stabilize Membrane Proteins While Retaining Lipid Interactions
Urner LH, Shutin D, Agasid MT, Robinson CV.Chemistry
December 2025 | Journal Article | Chemistry | Read
Sieving for Gold─An Efficient Method for Generating N-Heterocyclic Carbene Self-Assembled Monolayers on Nanostructured Gold Surfaces
Albino M, Georgiev D, Silva I, Fernandez Debets TFF, Liu M, Dell TN, Wojciechowski JP, Stevens MM
December 2025 | Journal Article | Journal of the American Chemical Society | Read
Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System
Grenier-Pleau IJ, Wells CJ, Holmes SM, Hall C, Vermeulen M, de Villiers CA, Penders J, Pedersen SV, Dick SA, Bonneil E, Slobodyanyuk M, Nagree MS, Kaur J, McNaughton AJM, Beaulieu J, Stevens MM, Xie SZ, Rauh MJ, Postovit LM, Knapp DJHF, Reimand J, Tyryshkin K, Thibault P, Craig AW, Rudan JF, Mann S, Chan EYW, Abraham SA
December 2025 | Journal Article | Journal of Extracellular Vesicles | Read
Is glymphatic clearance the secret to restorative sleep?
Hauglund NL, Nedergaard M.Brain
December 2025 | Journal Article (online ahead of print) | Brain | Read
Rapid screening of ethylene glycol and diethylene glycol in raw materials and medicinal syrups using low-cost field deployable assays
Arman BY, Legge I, Walsby-Tickle J, Bharucha T, Gabel J, Gnegel G, Deats M, Banerjee S, Stokes R, Merchant HA, Matousek P, McCullagh J, Caillet C, Newton PN, Zitzmann N, Gangadharan B
December 2025 | Journal Article | Scientific Reports | Read
Mechanism for a molecular assembler of sequence-controlled polymers using parallel DNA and a DNA polymerase
Bath J, Turberfield AJ
December 2025 | Journal Article (online ahead of print) | Nanoscale Horizons | Read
Circadian variability in breath volatiles is affected by the timing of inhaled corticosteroids in asthma
Wang R, Maidstone R, Ahmed W, Singh D, Ray D, Loudon A, Simpson A, Fowler SJ, Durrington HJ
December 2025 | Journal Article | ERJ Open Research | Read
Ultrasound-Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units
Brans VA, Constantinou AP, Kibble MJ, Nele V, Reumann D, Bau L, Callens SJP, Armstrong JPK, Newell N, Coussios CC, Stevens MM, Gray MD
December 2025 | Journal Article (online ahead of print) | Advanced Healthcare Materials | Read
Structural characterisation of the fungal Pmt4 homodimer
McDowell MA, Wild K, Fiorentino F, Bausewein D, Metschies A, Chiapparino A, Hackmann Y, Bilsing FL, Brenske D, Mortensen S, Wu D, Robinson CV, Strahl S, Sinning I
December 2025 | Journal Article | Nature Communications | Read
Semi-supervised Bayesian integration of multiple spatial proteomics datasets
Coleman S, Breckels L, Waller RF, Lilley KS, Wallace C, Crook OM, Kirk PDW
December 2025 | Journal Article | PLoS Computational Biology 2025 | Read
Structural snapshots of Pseudomonas aeruginosa LptB2FG and LptB2FGC reveal insights into lipopolysaccharide recognition and transport
Fiorentino F, Cervoni M, Wang Y, Urner LH, Sauer JB, Tran A, Corey RA, Rotili D, Mai A, Stansfeld PJ, Imperi F, Yu EW, Su CC, Robinson CV, Bolla JR
December 2025 | Journal Article | Nature Communications | Read
Challenges and Recommendations for Integrating Circadian Medicine in Critical Care: A Roadmap
Hiemstra FW, González LB, Engelhardt LJ, Hancke L, Pilz LK, Adler AI, Dashti HS, Drouot X, Kitchen GB, Knauert MP, Kramer A, Lipton JO, Luetz A, Maas MB, Pajor NM, Parthasarathy S, Spies C, van Westerloo DJ, Felten M, Klerman EB, Ray DW, Ruben MD, Roenneberg T, Kervezee L
December 2025 | Journal Article (online ahead of print) | Chest | Read
Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines
Arman BY, Magri A, Barbaglia MN, Petherbridge L, Brook J, Bharucha T, Legge I, Walsby-Tickle J, Deats M, Banerjee S, Mosca S, Jena R, Ranade DS, Chunekar SR, Patil KD, Gairola S, Merchant HA, Stokes R, Kuwana R, Maes A, James T, Green C, McCullagh J, Matousek P, Caillet C, Newton PN, Zitzmann N, Gangadharan B
December 2025 | Journal Article | International Journal of Pharmaceutics X | Read
Evidence of an activity-enhancing conformational shift in Arabidopsis thaliana plant cysteine oxidase 4 induced by binding of substrate or substrate-mimics
Latter R, Hintzen JCJ, Shah LMN, Gunawardana DM, Sher RM, White MD, Mecinović J, Benesch JLP, Flashman E
November 2025 | Journal Article | Journal of Biological Chemistry | Read
Light-induced conformational switching and magnetic sensitivity of Drosophila cryptochrome
Chandler SA, Gehrckens AS, Shah LMN, Buckton KE, Cao G, Sen N, Zollitsch T, Rodriguez R, Solov'yov IA, Schleicher E, Weber S, Hore PJ, Timmel CR, Mackenzie SR, Benesch JLP
November 2025 | Journal Article | Structure | Read
Visualizing intraorganellar ultrastructures, dynamics, and interactions with open-access background-free Lock-in-SIM
Liu W, Zhang M, Zhu W, Xie S, Zhang J, Qian S, Liu Z, Zheng X, Fang Q, Yang W, Wang Y, Zhu D, Dong J, Liu X, Chen Y, Kuang C, Zhang YH, Schermelleh L
November 2025 | Journal Article | Nature Communications | Read
Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder
Yan S, Sahoo A, Zerenner T, Marek K, Sommerauer M, Oertel W, Hu MT, Tofaris GK
November 2025 | Journal Article (online ahead of print) | Annals of Neurology | Read
Magnetically Retrievable Platinum Nanoreporters for Efficient Lateral Flow Immunoassay in Complex Bio-Samples
Cheng Y, Panariello L, Creamer A, Sadler CJ, Shamsabadi A, Lupien K, Vaughan A, Gervais T, Stevens MM
November 2025 | Journal Article (online ahead of print) | Small | Read
Structure of the conjugation surface exclusion protein TraT
Chen N, Bukys A, Lundgren CAK, Deme JC, El Sayyed H, Kapanidis AN, Lea SM, Berks BC
November 2025 | Journal Article | Communications Biology | Read
Update and new implementation of the MIRAGE reporting guidelines for mass spectrometry experiments in glycoscience
Lisacek F, Hackett WE, Thaysen-Andersen M, Karlsson NG, Klein J, Kolarich D, Maciej-Hulme ML, Okuda S, Packer NH, Struwe WB, Takahashi Y, Tiemeyer M, Zaia J, Aoki-Kinoshita KF, Kettner C
November 2025 | Journal Article (online ahead of print) | Molecular & Cellular Proteomics | Read
Increased risk of asthma in female night shift workers
Maidstone RJ, Ray DW, Liu J, Bowden J, Rutter MK, Durrington HJ
November 2025 | Journal Article | ERJ Open Research | Read
Hybrid Detergents Facilitate Scalable Charge Reduction and Stabilize Membrane Proteins While Retaining Lipid Interactions
Urner LH, Shutin D, Agasid MT, Robinson CV
November 2025 | Journal Article (online ahead of print) | Chemistry | Read
The G2019S LRRK2 mutation exacerbates α-synuclein and tau neuropathology through divergent pathways in Parkinson's disease models
Tsafaras G, Cabezudo D, Wetzels L, Tsakogias I, Abey A, Bentea E, Sanchiz-Calvo M, Van den Haute C, Wade-Martins R, Baekelandt V
November 2025 | Journal Article | Acta Neuropathologica | Read
Inferring residue level hydrogen deuterium exchange with ReX
Crook OM, Gittens N, Chung CW, Deane CM
November 2025 | Journal Article | Communications Chemistry | Read
Cerebellar organoids model cell type-specific FOXP2 expression during human cerebellar development
Apsley EJ, Riepsaame J, Cheng YC, Cowley SA, Becker EBE
November 2025 | Journal Article| Disease Models & Mechanisms | Read
Photo-PISA Driven In Situ Encapsulation of Nanocluster-Based Sensors within Stimuli-Responsive Polymersomes for AND Logic Gate Sensing
Chen K, Loynachan CN, Thanapongpibul C, Zhang J, Ma L, Yeow J, Najer A, Stevens MM
November 2025 | Journal Article | ACS Sensors | Read
Sleep stage can be selectively modulated through targeted deep brain stimulation of brainstem circuits
Deli A, Duchet B, He S, Huang Y, Martin S, Sanrangmat N, Divanbeighizand AP, Zamora M, Tan H, Vyazovskiy VV, Denison T, Green AL
November 2025 | Journal Article | Brain Stimulation | Read
SLC45A4 is a pain gene encoding a neuronal polyamine transporter
Middleton SJ, Markússon S, Åkerlund M, Deme JC, Tseng M, Li W, Zuberi SR, Kuteyi G, Sarkies P, Baskozos G, Perez-Sanchez J, Farah A, Hébert HL, Toikumo S, Yu Z, Maxwell S, Dong YY, Kessler BM, Kranzler HR, Linley JE, Smith BH, Lea SM, Parker JL, Lyssenko V, Newstead S, Bennett DL
October 2025 | Journal Article | Nature | Read
Vascularized and Perfusable Human Heart-on-a-Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery
Kim J, Zhang X, Wang R, Najer A, Lau QY, Cammack-Najera A, Kim JA, Kang YK, Xie R, Kim H, Xie K, Lim H, Park TE, Joo J, Stevens MM
October 2025 | Journal Article | Advanced Materials | Read
Perturbation of the circadian clock in chronic diseases involving organ fibrosis
Mukherji A, Tharaux PL, Ray DW, Baumert TF
October 2025 | Journal Article | Journal of Clinical Investigation | Read
Sprayable extracellular matrix hydrogel reduces postoperative adhesion formation and protects healing tissues in preclinical models
Pascual-Antón L, Sandoval P, Tomero-Sanz H, Terri M, Strippoli R, García-Sanz Í, Marín-Campos C, Del Pozo MÁ, Obaid M, Garcia V, Smith PA, Keane TJ, Stevens MM, López-Cabrera M
October 2025 | Journal Article | Science Translational Medicine | Read
The future of education in sleep science and medicine in Europe: Report of an ESRS workshop
McNicholas WT, Arnardottir ES, Vyazovskiy VV, Pevernagie D, Penzel T, Peigneux P, Grote L, Van Der Werf Y, de Jongh F, Schmidt M, Adamantidis M, Sekaran S, Biller AM, Knobl B, Luppi PH, Bassetti CL, Paunio T
October 2025 | Journal Article| Journal of Sleep Research | Read
Convergence of nanotechnology and CRISPR-based diagnostics
Johnston M, Dissanayake-Perera S, Collins JJ, Stevens MM, Dincer C
October 2025 | Journal Article | Nature Nanotechnology | Read
Evaluation of Malaria Parasite Transmission Competency Using a Nanozyme-Based Immunodiagnostic Targeting Female Gamete Antigen Release
Haghighi T, Najer A, Broto M, Dahalan FA, Churchyard A, Yahiya S, Famodimu MT, Tunnicliff M, Abdelwahed A, Tachibana M, Ishino T, Aniweh Y, Awandare GA, Mahamar A, Vanheer LN, Bousema T, Drakeley C, Dicko A, Stone W, Baum J, Stevens MM
October 2025 | Journal Article | ACS Nano | Read
Uncovering hidden protein modifications with native top-down mass spectrometry
Bennett JL, El-Baba TJ, Zouboulis KC, Kirschbaum C, Song H, Butroid FI, Benesch JLP, Lutomski CA, Robinson CV
October 2025 | Journal Article | Nature Methods | Read
Native mass spectrometry of membrane proteins reconstituted in peptidiscs
Deedwania A, Wang Y, Robinson CV, Bolla JR
October 2025 | Journal Article (online ahead of print) | RSC Chemical Biology | Read
Smart Healthcare Photonic Nanomaterials and Devices
Stevens MM, Rogers JA, Hahn SK
October 2025 | Journal Article (online ahead of print) | Advanced Materials | Read
N-terminal Half of MED14 is critical for Mediator-RNA Polymerase II Interaction and the Resulting Transcription
Baris Y, Jabbar J, Yozgat Y, Dinccelik-Aslan M, Cigirgan E, Erden M, Bay S, Aslan V, Cevher MA.
October 2025 | Journal Article (online ahead of print) | Journal of Biological Chemistry | Read
High-throughput single-virion DNA-PAINT reveals structural diversity, cooperativity, and flexibility during selective packaging in influenza
Hepp C, Zhao Q, Robb N, Fodor E, Kapanidis AN
October 2025 | Journal Article | Nucleic Acids Research | Read
Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts
Ye M, Makola M, Richards MW, Newman JA, Fairhead M, Burgess SG, Wu Z, Maclean E, Wright ND, Koekemoer L, Thompson A, Bezerra GA, Yi G, Li H, Rangel VL, Mamalis D, Aitkenhead H, Davis BG, Gilbert RJC, Duerr KL, Bayliss R, Gileadi O, von Delft F
October 2025 | Journal Article | ACS Central Science Journal | Read
Best practice mass photometry: a guide to optimal single-molecule mass measurement
Kratochvíl J, van Wee R, Thiele JC, Loewenthal D, Bardzil J, Iqbal K, Benesch JLP, Thorpe S, Kukura P
October 2025 | Journal Article (online ahead of print) | Nature Protocols | Read
Sleep stage can be selectively modulated through targeted deep brain stimulation of brainstem circuits
Deli A, Duchet B, He S, Huang Y, Martin S, Sanrangmat N, Divanbeighizand AP, Zamora M, Tan H, Vyazovskiy VV, Denison T, Green AL
October 2025 | Journal Article (online ahead of print) | Brain Stimulation | Read
Small-molecule dissolution of stress granules by redox modulation benefits ALS models
Uechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I, Martinez EJ, Boczek E, Wagner M, Tomschke N, de Jesus Domingues AM, Pal A, Doeleman T, Kour S, Anderson EN, Stein F, Lee HO, Zhang X, Fritsch AW, Jahnel M, Fürsch J, Murthy AC, Alberti S, Bickle M, Fawzi NL, Nadler A, David DC, Pandey UB, Hermann A, Stengel F, Davis BG, Baldwin AJ, Savitski MM, Hyman AA, Wheeler RJ
October 2025 | Journal Article | Nature Chemical Biology | Read
Peripheral neuronal sensitization and neurovascular remodelling in osteoarthritis pain
Batchelor V, Perry TA, Cader MZ, Vincent TL
September 2025 | Journal Article | Nature Reviews Rheumatology | Read
Localized growth factor delivery from microparticles modulates osteogenic and chondrogenic gene expression in a growth factor-dependent manner in an ex vivo chick embryonic bone model
Rashidi H, Cox HC, Qutachi O, Moulding D, White LJ, Smith EL, Kanczler JM, Rojo L, Rotherham M, Henstock JR, Stevens MM, Haj AJE, Oreffo ROC, Shakesheff KM, Rose FRAJ
September 2025 | Journal Article | Acta Biomaterialia | Read
Overcoming the Speed Limit of Four-Way DNA Branch Migration with Bulges in Toeholds
Bakhtawar S, Smith F, Sengar A, Stan GV, Goertz J, Stevens MM, Ouldridge TE, Bae W
September 2025 | Journal Article | Nano Letters | Read
Deep Structural Characterization of Protein-Bound Lipids via Native MS and Ultraviolet Photodissociation
Kirschbaum C, Bennett JL, Robinson CV
September 2025 | Journal Article | Analytical Chemistry | Read
Galectin-3 induces neurodevelopmental apical-basal polarity and regulates gyrification
Soares LC, Huang N, Bernhardova H, Macarelli V, Chan M, Nikel L, Bandiera S, Yan D, Gupta D, Cruz EM, Vasaturo-Kolodner T, Hillis JM, Wood M, Salman M, Molnár Z, O'Neill E, Szele FG
September 2025 | Journal Article | Science Advances | Read
Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines
Alam N, Farrell B, Jamwal A, Higgins MK
September 2025 | Journal Article (online ahead of print) | Nature Reviews Microbiology | Read
Epilepsy Research Institute Partner Symposium: Radically advancing research into epilepsy
Richardson A, Mengual JP, Marichal N, Hills K, Price L
September 2025 | Journal Article | Brain and Neuroscience Advances | Read
The displacement of the σ70 finger in initial transcription is highly heterogeneous and promoter-dependent
Wang A, Fletcher A, Mukherjee P, Grainger DC, Mazumder A, Kapanidis AN
September 2025 | Journal Article | Nucleic Acids Research | Read
Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages
Khan I, MacDonald SJ, Markússon S, Kies PJ, Kraemer-Zimpel C, Robson C, Parker JL, Newstead S, Boucher D, Hammer ND, Van Der Woude M, Thomas GH
September 2025 | Journal Article | PLoS Pathogens | Read
In vivo validation of novel non-invasive PHP.eB AAVs as a potential therapeutic approach for alpha-synucleinopathies
Fouka M, Tsakogias I, Gialinaki EG, Stavropoulos A, Volbracht C, De Muynck L, Moechars D, Melki R, Tofaris GK, Stefanis L, Xilouri M
September 2025 | Journal Article | Acta Neuropathologica Communications | Read
SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides
Loreto A, Cramb KML, McDermott LA, Antoniou C, Cirilli I, Caiazza MC, Merlini E, Arthur-Farraj P, du Preez WD, Mock ED, Zhao HT, Bennett DL, Orsomando G, Coleman MP, Wade-Martins R
September 2025 | Journal Article | Neurobiology of Disease | Read
Liquid Bridges Mediate Crack Initiation, Propagation, and Coalescence to Suppress Film Failure within Flexible Electronics
Peng S, Zhao Y, Li Z, Dong H, Ji X, Chu Z, Yin J, He H, Guo W, Zheng S
September 2025 | Journal Article | Advanced Materials | Read
Cell cycle regulation has shaped replication origins in budding yeast
Lim CT, Miller TCR, Tan KW, Talele S, Early A, East P, Sánchez H, Dekker NH, Costa A, Diffley JFX
September 2025 | Journal Article | Nature Structural & Molecular Biology | Read
The molecular circadian clock: From fundamental mechanisms to therapeutic promise in neurological disorders
Campbell-Galland A, Bafna A, Jagannath A
September 2025 | journal Article | Advanced Drug Delivery Reviews | Read
SLC45A4 is a Pain Gene Encoding a Neuronal Polyamine Transporter
Middleton SJ, Markússon S, Åkerlund M, Deme JC, Tseng M, Li W, Zuberi SR, Kuteyi G, Sarkies P, Baskozos G, Perez-Sanchez J, Farah A, Hébert HL, Toikumo S, Yu Z, Maxwell S, Dong YY, Kessler BM, Kranzler HR, Linley JE, Smith BH, Lea SM, Parker JL, Lyssenko V, Newstead S, Bennett DL
August 2025 I Journal Article I Nature I Read
SARM1 Activation Induces Reversible Mitochondrial Dysfunction and can be Prevented in Human Neurons by Antisense Oligonucleotides
Loreto A, Cramb KML, McDermott LA, Antoniou C, Cirilli I, Caiazza MC, Merlini E, Arthur-Farraj P, du Preez WD, Mock ED, Zhao HT, Bennett DL, Orsomando G, Coleman MP, Wade-Martins R
August 2025 I Journal Article I Neurobiology of Disease I Read
Peripheral Neuronal Sensitization and Neurovascular Remodelling in Osteoarthritis Pain
Batchelor V, Perry TA, Cader MZ, Vincent TL
August 2025 I Journal Article I Nature Reviews Rheumatology I Read
NIPBL and STAG1 Enable Loop Extrusion by Providing Differential DNA-cohesin Affinity
van Wee R, Asor R, Li Y, Drechsel D, Popova M, Litos G, Davidson IF, Peters JM, Kukura P
August 2025 I Journal Article I PNAS I Read
The Molecular Circadian Clock: From Fundamental Mechanisms to Therapeutic Promise in Neurological Disorders
Campbell-Galland A, Bafna A, Jagannath A
August 2025 I Journal Article I Advanced Drug Delivery Reviews I Read
Light-induced Conformational Switching and Magnetic Sensitivity of Drosophila Cryptochrome
Chandler SA, Gehrckens AS, Shah LMN, Buckton KE, Cao G, Sen N, Zollitsch T, Rodriguez R, Solov'yov IA, Schleicher E, Weber S, Hore PJ, Timmel CR, Mackenzie SR, Benesch JLP
August 2025 I Journal Article I Structure I Read
Structural Basis for Transport and Inhibition of Nucleotide Sugar Transport in Pathogenic Fungi
Parker JL, Deme JC, Feddersen B, Lea SM, Newstead S
August 2025 I Journal Article I Research Square I Read
Deep Structural Characterization of Protein-Bound Lipids via Native MS and Ultraviolet Photodissociation
Kirschbaum C, Bennett JL, Robinson CV
August 2025 I Journal Article I Analytical Chemistry I Read
Cryo-EM Led Analysis of Open and Closed Conformations of Chagas Vaccine Candidate TcPOP
Batra S, Olmo F, Ragan TJ, Kaplan M, Calvaresi V, Frank AM, Lancey C, Assadipapari M, Ying C, Struwe WB, Hesketh EL, Kelly JM, Barfod L, Campeotto I
August 2025 I Journal Article I Nature Communications I Read
Liquid Bridges Mediate Crack Initiation, Propagation, and Coalescence to Suppress Film Failure within Flexible Electronics
Peng S, Zhao Y, Li Z, Dong H, Ji X, Chu Z, Yin J, He H, Guo W, Zheng S
August 2025 I Journal Article I Advanced Materials I Read
Optogenetic Vision Restoration in the Face of Secondary and Tertiary Remodeling in the rd1 Mouse Retina
Hughes S, Rodgers J, Lindner M, Peirson SN, Lucas RJ, Hankins MW
August 2025 I Journal Article I Molecular Therapy I Read
Localized Growth Factor Delivery from Microparticles Modulates Osteogenic and Chondrogenic Gene Expression in a Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model
Rashidi H, Cox HC, Qutachi O, Moulding D, White LJ, Smith EL, Kanczler JM, Rojo L, Rotherham M, Henstock JR, Stevens MM, Haj AJE, Oreffo ROC, Shakesheff KM, Rose FRAJ
August 2025 I Journal Article I Acta Biomaterialia I Read
Plasmodium Falciparum Infection Induces T cell Tolerance that is Associated with Decreased Disease Severity upon Re-infection
Muñoz Sandoval D, Bach FA, Ivens A, Harding AC, Smith NL, Mazurczyk M, Themistocleous Y, Edwards NJ, Silk SE, Barrett JR, Cowan GJM, Napolitani G, Savill NJ, Draper SJ, Minassian AM, Nahrendorf W, Spence PJ
July 2025 I Journal Article I Journal of Experimental Magazine I Read
Permanent Magnetic Droplet-derived Microrobots
Cao Y, Xie R, Schönhöfer PWA, Burdis R, Wang R, Sun R, Xie K, Zou J, Song X, Lau QY, Lin J, Kim JA, Georgiev D, Tang J, Ng HC, Bibikova O, Zuo Y, Lu XL, Glotzer SC, Stevens MM
July 2025 I Journal Article I Science Advances I Read
RIFINs Displayed on Malaria-infected Erythrocytes Bind KIR2DL1 and KIR2DS1
Sakoguchi A, Chamberlain SG, Mørch AM, Widdess M, Harrison TE, Dustin ML, Arase H, Higgins MK, Iwanaga S
July 2025 I Journal Article I Nature I Read
Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications
Yang R, Ma X, Xuan M, Ma Y, Ding J, Chau DYS, Knowles JC, Peng F, Poma A
July 2025 I Chemistry Europe I Read
Cryo-EM Structure of the Human THIK-1 K2P K+ Channel Reveals a Lower Y Gate Regulated by Lipids and Anesthetics
Rödström KEJ, Eymsh B, Proks P, Hayre MS, Cordeiro S, Mendez-Otalvaro E, Madry C, Rowland A, Kopec W, Newstead S, Baukrowitz T, Schewe M, Tucker SJ
July 2025 I Nature Structural & Molecular Biology I Read
Telmisartan is Neuroprotective in a hiPSC-derived Spinal Microtissue Model for C9orf72 ALS via Inhibition of Neuroinflammation
Sonustun B, Vahsen BF, Ledesma-Terrón M, Li Z, Tuffery L, Xu N, Calder EL, Jungverdorben J, Weber L, Zhong A, Miguez DG, Monetti M, Zhou T, Giacomelli E, Studer L
July 2025 I Stem Cell Reports I Read
The Molecular Circadian Clock: From Fundamental Mechanisms to Therapeutic Promise in Neurological Disorders
Campbell-Galland A, Bafna A, Jagannath A
July 2025 I Advanced Drug Delivery Reviews I Read
Scavenger Receptor CD163 Multimerises to Allow Uptake of Diverse Ligands
Zhou RX, Higgins MK
July 2025 I Nature Communications I Read
Single-Molecule Imaging for Unraveling the Functional Diversity of 10-23 DNAzymes
Montserrat Pagès A, Kümmerlin M, Andrews R, Kapanidis AN, Spasic D, Lammertyn J
July 2025 I Analytical Chemistry I Read
Immunoassay for Pyruvate Kinase M1/2 as an Alzheimer's Biomarker in CSF
de Geus MB, Kivisäkk P, Trombetta BA, Tijms BM, Visser PJ, Arnold SE, Carlyle BC
July 2025 I Open Life Sciences I Read
Vascularized and Perfusable Human Heart-on-a-Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery
Kim J, Zhang X, Wang R, Najer A, Lau QY, Cammack-Najera A, Kim JA, Kang YK, Xie R, Kim H, Xie K, Lim H, Park TE, Joo J, Stevens MM
July 2025 I Advanced Materials I Read
RIFINs Displayed on Malaria-infected Erythrocytes Bind KIR2DL1 and KIR2DS1
Sakoguchi A, Chamberlain SG, Mørch AM, Widdess M, Harrison TE, Dustin ML, Arase H, Higgins MK, Iwanaga S
June 2025 I Journal Article I Nature I Read
Immune Evasion Runs in the Family: Two Surface Protein Families of Plasmodium Falciparum-infected Erythrocytes
Chamberlain SG, Iwanaga S, Higgins MK
June 2025 I Journal Article I Current Opinion in Microbiology I Read
Membrane Protein Complexity Revealed Through Native Mass Spectrometry
Lawrence SAS, Dolan A, Miller MM, Robinson CV
June 2025 I Journal Article I Annual Review of Biochemistry I Read
Designing Physical Unclonable Functions From Optically Active Materials
Klausen M, Zhang J, Stevens MM
June 2025 I Journal Article I Advanced Materials I Read
Extracellular Vesicles in TDP-43 Proteinopathies: Pathogenesis and Biomarker Potentia
Dellar ER, Nikel L, Fowler S, Vahsen BF, Dafinca R, Feneberg E, Talbot K, Turner MR, Thompson AG
June 2025 I Journal Article I Molecular Neurodegeneration I Read
Single-Molecule Imaging for Unraveling the Functional Diversity of 10-23 DNAzymes
Montserrat Pagès A, Kümmerlin M, Andrews R, Kapanidis AN, Spasic D, Lammertyn J
June 2025 I Journal Article I Analytical Chemistry I Read
Controlling DNA-RNA Strand Displacement Kinetics with Base Distribution
Ratajczyk EJ, Bath J, Šulc P, Doye JPK, Louis AA, Turberfield AJ
June 2025 I Journal Article I PNAS I Read
Interaction between Native and Prosthetic Visual Responses in Optogenetic Visual Restoration
Carpentiero E, Hughes S, Rodgers J, Xhaferri N, Biswas S, Gilhooley MJ, Hankins MW, Lindner M
June 2025 I Journal Article I JCI Insight I Read
Handheld Spatially Offset Raman Spectroscopy for Rapid Non-invasive Detection of Ethylene Glycol and Diethylene Glycol in Medicinal Syrups
Banerjee S, Mosca S, Legge I, Gangadharan B, Walsby-Tickle J, Arman BY, Stokes R, Bharucha T, Deats M, Merchant HA, McCullagh J, Zitzmann N, Caillet C, Newton PN, Matousek P
June 2025 I Journal Article I Journal of Pharmaceutical and Biomedical Analysis I Read
Formation of Seeding-competent α-synuclein Aggregates in Parkin-deficient iPSC-derived Human Neurons
Schmidt SI, Okarmus J, Madsen DA, Hansen JS, Gregersen E, Gram H, Winkelmann LS, Oliveira AS, Heon-Roberts R, Ryan BJ, Freude K, Blaabjerg M, Jensen PH, Meyer M
June 2025 I Journal Article I NPJ Parkinson's Disease I Read
SARM1 Activation Induces Reversible Mitochondrial Dysfunction and can be Prevented in Human Neurons by Antisense Oligonucleotides
Loreto A, Cramb KML, McDermott LA, Antoniou C, Cirilli I, Caiazza MC, Merlini E, Arthur-Farraj P, du Preez WD, Mock ED, Zhao HT, Bennett DL, Orsomando G, Coleman MP, Wade-Martins R
June 2025 I Journal Article I Neurobiology of Disease I Read
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Han M, Lin W, Cao Y, Murray P, Wilm B, McWilliam SJ, Curran J, Xie R
June 2025 I Journal Article I Advanced Healthcare Materials I Read
Hydrophobic And Polarized Aromatic Residues Promote Internalization Of Arg-Rich Cell Penetrating Peptides Through Ionpair-π Interactions
Khemaissa S, Bauzá A, Lesur É, Illien F, Sagan S, Frontera A, Walrant A
June 2025 I Journal Article I Chemistry I Read
Telmisartan is Neuroprotective in a hiPSC-derived Spinal Microtissue Model for C9orf72 ALS via Inhibition of Neuroinflammation
Sonustun B, Vahsen BF, Ledesma-Terrón M, Li Z, Tuffery L, Xu N, Calder EL, Jungverdorben J, Weber L, Zhong A, Miguez DG, Monetti M, Zhou T, Giacomelli E, Studer L
June 2025 I Journal Article I Stem Cell Reports I Read
Liquid Bridges Mediate Crack Initiation, Propagation, and Coalescence to Suppress Film Failure within Flexible Electronics
Peng S, Zhao Y, Li Z, Dong H, Ji X, Chu Z, Yin J, He H, Guo W, Zheng S
June 2025 I Journal Article I Advanced Materials I Read
Mass Photometry
Asor R, Loewenthal D, van Wee R, Benesch JLP, Kukura P
May 2025 I Journal Article I Annual Review of Biophysics I Read
Proteomics Analysis of Peripheral Blood Mononuclear Cells from Patients in Early Dengue Infection Reveals Potential Markers of Subsequent Fluid Leakage
Perera N, Kumar A, Gangadharan B, Ranasinghe D, Wijewickrama A, Malavige GN, Miller JL, Zitzmann N
May 2025 I Journal Article I Viruses I Read
Recent Developments in Gene Therapy for Parkinson's Disease
Szunyogh S, Carroll E, Wade-Martins R
May 2025 I Journal article I Molecular Therapy I Read
Small-molecule Dissolution of Stress Granules by Redox Modulation Benefits ALS Models
Uechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I, Martinez EJ, Boczek E, Wagner M, Tomschke N, de Jesus Domingues AM, Pal A, Doeleman T, Kour S, Anderson EN, Stein F, Lee HO, Zhang X, Fritsch AW, Jahnel M, Fürsch J, Murthy AC, Alberti S, Bickle M, Fawzi NL, Nadler A, David DC, Pandey UB, Hermann A, Stengel F, Davis BG, Baldwin AJ, Savitski MM, Hyman AA, Wheeler RJ
May 2025 I Journal article I Nature Chemical Biology I Read
Safety and Efficacy of the Blood-stage Malaria Vaccine RH5.1/Matrix-M in Burkina Faso: Interim Results of a Double-blind, Randomised, Controlled, Phase 2b Trial in Children
Natama HM, Salkeld J, Somé A, Soremekun S, Diallo S, Traoré O, Rouamba T, Ouédraogo F, Ouédraogo E, Daboné KCS, Koné NA, Compaoré ZMJ, Kafando M, Bonko MDA, Konaté F, Sorgho H, Nielsen CM, Pipini D, Diouf A, King LDW, Shaligram U, Long CA, Cho JS, Lawrie AM, Skinner K, Roberts R, Miura K, Bradley J, Silk SE, Draper SJ, Tinto H, Minassian AM
May 2025 I Journal article I The Lancet Infectious Diseases I Read
Cytomimetic Calcification in Chemically Self-regulated Prototissues
Sun R, Yin Z, Stevens MM, Li M, Mann S
May 2025 I Journal article I Nature Communications I Read
Enhanced Interferometric Imaging by Rotating Coherent Scattering Microscopy
Iqbal K, Thiele JC, Pfitzner E, Kukura P
May 2025 I Journal article I ACS Photonics I Read
Signal Enhancement in Immunoassays via Coupling to Catalytic Nanoparticles
Sadler CJ, Sandler JP, Shamsabadi A, Frenette LC, Creamer A, Stevens MM
May 2025 I Journal article I ACS Sensors I Read
Measurements of Molecular Size and Shape on a Chip
Zhu X, Bennett TJD, Zouboulis KC, Soulias D, Grzybek M, Benesch JLP, El-Sagheer AH, Coskun Ü, Krishnan M
May 2025 I Journal article I Science I Read
Filamin C Dimerisation is Regulated by HSPB7
Wang Z, Cao G, Collier MP, Qiu X, Broadway-Stringer S, Šaman D, Ng JZY, Sen N, Azad AJ, Hooper C, Zimmermann J, McDonough MA, Brem J, Rabe P, Song H, Alderson TR, Schofield CJ, Bolla JR, Djinovic-Carugo K, Fürst DO, Warscheid B, Degiacomi MT, Allison TM, Hochberg GKA, Robinson CV, Gehmlich K, Benesch JLP
May 2025 I Journal article I Nature Communications I Read
Assessment of Repurposed Compounds Against Coronaviruses Highlights the Antiviral Broad-spectrum Activity of Host-targeting Iminosugars and Confirms the Activity of Potent Directly Acting Antivirals
Brun J, Arman BY, Hill ML, Kiappes JL, Alonzi DS, Makower LL, Witt KD, Gileadi C, Rangel V, Dwek RA, von Delft A, Zitzmann N
May 2025 I Journal article I Antiviral Research I Read
In Reply to Letter to the Editor from Paudel: Comment on "Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers"
Buckley NJ, Rowland HA
May 2025 I Journal article I Stem Cells I Read
Preclinical Models for Schizophrenia and Sleep Oscillations: From Biomarkers to Mechanisms
Vyazovskiy VV, Bannerman
April 2025 I Journal Article I Biological Psychiatry I Read
Traversing the drug discovery landscape using native mass spectrometry
Britt HM, Robinson CV
April 2025 I Journal article I Current Opinion in Structural Biology I Read
Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice
Guillaumin MCC, Harding CD, Krone LB, Yamagata T, Kahn MC, Blanco-Duque C, Banks GT, Achermann P, Diniz Behn C, Nolan PM, Peirson SN, Vyazovskiy VV
April 2025 I Journal article, I Current Biology I Read
Drug repurposing in amyotrophic lateral sclerosis (ALS)
Carroll E, Scaber J, Huber KVM, Brennan PE, Thompson AG, Turner MR, Talbot K
April 2025 I Journal article I Expert Opinion on Drug Discovery I Read
Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5
Chen ZS, Peng SI, Leong LI, Gall-Duncan T, Wong NSJ, Li TH, Lin X, Wei Y, Koon AC, Huang J, Sun JK, Turner C, Tippett L, Curtis MA, Faull RLM, Kwan KM, Chow HM, Ko H, Chan TF, Talbot K, Pearson CE, Chan HYE
April 2025 I Journal article I Nature Communications I Read
Molecular basis for the phosphorylation of bacterial tyrosine kinase Wzc
Yang Y, Batista M, Clarke BR, Agyare-Tabbi MR, Song H, Kuehfuss NM, Le Bas A, Robinson CV, Whitfield C, Stansfeld PJ, Naismith JH, Liu J
April 2025 I Journal article I Nature Communications I Read
Nanoscale Biodegradable Printing for Designed Tuneability of Vaccine Delivery Kinetics
Peeler DJ, Sun R, Kütahya C, Peschke P, Zhou K, Brachi G, Yeow J, Rifaie-Graham O, Wojciechowski JP, Fernandez Debets TFF, LaLone V, Song X, Polra K, McKay PF, Tregoning JS, Shattock RJ, Stevens MM
April 2025 I Journal article I Advanced Materials I Read
Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice-Switching Oligonucleotides
Ojansivu M, Barriga HMG, Holme MN, Morf S, Doutch JJ, Andaloussi SE, Kjellman T, Johnsson M, Barauskas J, Stevens MM
April 2025 I Journal article I Advanced Materials I Read
Following phospholipid transfer through the OmpF3-MlaA-MlaC lipid shuttle with native mass spectrometry
Kirschbaum C, Bennett JL, Tian Q, Sen N, Smith IPS, Wu D, Benesch JLP, Khalid S, Isom G, Robinson CV
April 2025 I Journal article I Proceedings of the National Academy of Sciences of the United States I Read
Adding a Twist to Lateral Flow Immunoassays: A Direct Replacement of Antibodies with Helical Affibodies, from Selection to Application
Sadler CJ, Creamer A, Giang KA, Darmawan KK, Shamsabadi A, Richards DA, Nilvebrant J, Wojciechowski JP, Charchar P, Burdis R, Smith F, Yarovsky I, Nygren PÅ, Stevens MM
April 2025 I Journal article I Journal of the American Chemical Society I Read
Self-Doped and Biodegradable Glycosaminoglycan-PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC-Derived Cardiomyocytes
Hachim D, Hernández-Cruz O, Foote JEJ, Wang R, Delahaye MW, Stuckey DJ, Feng Z, Wojciechowski JP, Salter LCB, Lin J, Harding SE, Stevens MM
April 2025 I Journal article I Advanced Healthcare Materials I Read
Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Skerle JL, Persson LJ, Anden O, Oluwole AO, Howard RJ, Lindahl E, Robinson CV, Strisovsky K, Marklund EG, Drew D, Stansfeld PJ, Landreh M
April 2025 I Journal article I eLife Sciences Publications I Read
Immune evasion runs in the family: two surface protein families of Plasmodium falciparum-infected erythrocytes
Chamberlain SG, Iwanaga S, Higgins MK
March 2025 I Journal Article I Current Opinion in Microbiology I Read
The resurgence of monkeypox clade Ib: a global health emergency and concern
Kumar S, Subramaniam G, Senthil Kumar KJ
March 2025 I Journal Article I Archives of Virology I Read
Recent developments in gene therapy for Parkinson's disease
Szunyogh S, Carroll E, Wade-Martins
March 2025 I Journal Article I Molecular Therapy I Read
Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers
Rowland HA, Miller G, Liu Q, Li S, Sharp NR, Ng B, Wei T, Arunasalam K, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Kocagoncu E, Lawson J, Malhotra P, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Zetterberg H, Cader MZ, Wade-Martins R, Lovestone S, Nevado-Holgado A, Kormilitzin A, Buckley NJ
March 2025 I Journal article I Stem Cells I Read
Investigating the role of elastin and extracellular matrix damage in cardiovascular calcification
Radvar E, Mehta K, D'Ambrosio A, Mastroianni G, Al-Jawad M, Stevens MM, Mata A, Elsharkawy
March 2025 I Journal article I Journal of Structural Biology I Read
Structure and mechanism of the Zorya anti-phage defence system
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
March 2025 I Journal article I Nature I Read
STD NMR Epitope Perturbation by Mutation Unveils the Mechanism of YM155 as an Arginine-Glycosyltransferases Inhibitor Effective in Treating Enteropathogenic Diseases
Ramírez-Cárdenas J, Taleb V, Calvaresi V, Struwe WB, El Qaidi S, Zhu C, Hasan K, Zhang Y, Hardwidge PR, Veloz B, Muñoz-García JC, Hurtado-Guerrero R, Angulo J
March 2025 I Journal article I Journal of the American Chemical Society I Read
Measuring glymphatic function: assessing the toolkit
Ayyappan K, Unger L, Kitchen P, Bill RM, Salman MM
March 2025 I Journal article INeural Regeneration Research I Read
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers
Dellar ER, Vendrell I, Amein B, Lester DG, Edmond EC, Yoganathan K, Dharmadasa T, Sogorb-Esteve A, Fischer R, Talbot K, Rohrer JD, Turner MR, Thompson AG
March 2025 I Journal article I Annals of Neurology I Read
Unbiased CSF Proteomics in Patients With Idiopathic Normal Pressure Hydrocephalus to Identify Molecular Signatures and Candidate Biomarkers
de Geus MB, Wu CY, Dodge H, Leslie SN, Wang W, Lam TT, Kahle KT, Chan D, Kivisäkk P, Nairn AC, Arnold SE, Carlyle BC
March 2025 I Journal article I Neurology I Read
Sleep-wake-related changes in intracellular chloride regulate plasticity at glutamatergic cortical synapses
Alfonsa H, Chakrabarty A, Vyazovskiy VV, Akerman CJ
March 2025 I Journal article I Current Biology I Read
Nano-confined controllable crystallization in supramolecular polymeric membranes for ultra-selective desalination
Lu G, A H, Zhao Y, Zhao Y, Xu H, Shang W, Chen X, Sun J, Zhang H, Wu J, Dai B, Van der Bruggen B, Dewil R, An AK, Zheng S
March 2025 I Journal article I Nature Communications I Read
Chemical control of colloidal self-assembly driven by the electrosolvation force
Wang S, Walker-Gibbons R, Watkins B, Lin B, Krishnan M
March 2025 I Journal article I Nature Communications I Read
Enhanced restoration of visual code after targeting ON bipolar cells compared with retinal ganglion cells with optogenetic therapy
Rodgers J, Hughes S, Ebrahimi AS, Allen AE, Storchi R, Lindner M, Peirson SN, Badea TC, Hankins MW, Lucas RJ
March 2025 I Journal article I Molecular Therapy I Read
Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson's disease
Yan S, Zhang W, Li X, Dutta S, Castle AR, Liu Y, Sahoo A, Lam CL, Gatford NJF, Hu MT, Li CZ, Jiang C, Shu B, Tofaris GK
March 2025 I Journal Article I Cell Reports Medicine I Read
Human Metapneumovirus (HMPV) Outbreak: An Urgent Call for Enhanced Surveillance and Public Health Action
Kumar S, Subramaniam G, Senthil Kumar KJ
February 2025 I Journal article I Journal of Medical Virology I Read
Surface polarization strongly influences electrostatics in a nonlocal medium
Behjatian A, Blossey R, Krishnan M
February 2025 I Journal article I Journal of Chemical Physics I Read
The future of education in sleep science and medicine in Europe: Report of an ESRS workshop
McNicholas WT, Arnardottir ES, Vyazovskiy VV, Pevernagie D, Penzel T, Peigneux P, Grote L, Van Der Werf Y, de Jongh F, Schmidt M, Adamantidis M, Sekaran S, Biller AM, Knobl B, Luppi PH, Bassetti CL, Paunio T
February 2025 I Journal article I Journal of Sleep Research I Read
Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation
Kuijpers L, Giannopoulou EA, Feng Y, van den Braak W, Freydoonian A, Ramlal R, Meiring H, Solano B, Roos WH, Jakobi AJ, van der Pol LA, Dekker NH
February 2025 I Journal article I PLOS Pathogens I Read
Ribosome phenotypes for rapid classification of antibiotic-susceptible and resistant strains of Escherichia coli
Farrar A, Turner P, El Sayyed H, Feehily C, Chatzimichail S, Ta S, Crook D, Andersson M, Oakley S, Barrett L, Nellåker C, Stoesser N, Kapanidis A
February 2025 I Journal article I Communications Biology I Read
Defining proteoform-specific interactions for drug targeting in a native cell signalling environment
Lutomski CA, Bennett JL, El-Baba TJ, Wu D, Hinkle JD, Burnap SA, Liko I, Mullen C, Syka JEP, Struwe WB, Robinson CV
February 2025 I Journal article I Nature Chemistry I Read
Predicting substrates for orphan solute carrier proteins using multi-omics datasets
Zhang Y, Newstead S, Sarkies P
February 2025 I Journal article I BMC Genomics I Read
Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics
Rödström KEJ, Eymsh B, Proks P, Hayre MS, Cordeiro S, Mendez-Otalvaro E, Madry C, Rowland A, Kopec W, Newstead S, Baukrowitz T, Schewe M, Tucker SJ
February 2025 I Journal article I Nature Structural & Molecular Biology I Read
Native MS-guided Lipidomics to Define Endogenous Lipid Microenvironments of Eukaryotic Receptors and Transporters
Wu D, Tang H, Qiu X, Song S, Chen S, Robinson CV
January 2025 | Journal article | Nature Protocols | Read
Structures of TASK-1 and TASK-3 K2P Channels Provide Insight into Their Gating and Dysfunction in Disease
Hall PR, Jouen-Tachoire T, Schewe M, Proks P, Baukrowitz T, Carpenter EP, Newstead S, Rödström KEJ, Tucker SJ
January 2025 | Journal article | Structure | Read
ARSACS: Clinical Features, Pathophysiology and iPS-Derived Models
Salem IH, Blais M, Zuluaga-Sánchez VM, Rouleau L, Becker EBE, Dupré N
January 2025 | Journal article | Cerebellum | Read
Defining Proteoform-Specific Interactions for Drug Targeting in a Native Cell Signalling Environment
Lutomski CA, Bennett JL, El-Baba TJ, Wu D, Hinkle JD, Burnap SA, Liko I, Mullen C, Syka JEP, Struwe WB, Robinson CV
January 2025 | Journal article | Nature Chemistry | Read
Evaluation of the Digital Ventilated Cage® System for Circadian Phenotyping
Tir S, Foster RG, Peirson SN
January 2025 | Journal article | Scientific Reports | Read
Identifying Falsified COVID-19 Vaccines by Analysing Vaccine Vial Label and Excipient Profiles Using MALDI-ToF Mass Spectrometry
Arman BY, Clarke R, Bharucha T, Fernandez LG, Walsby-Tickle J, Deats M, Mosca S, Lin Q, Banerjee S, Chunekar SR, Patil KD, Gairola S, Dunachie S, Merchant HA, Stokes R, Kuwana R, Maes A, Charrier JP, Probert F, Caillet C, Matousek P, McCullagh J, Newton PN, Zitzmann N, Gangadharan B
January 2025 | Journal article | NPJ Vaccines | Read
Bright and Stable Anti-Counterfeiting Devices with Independent Stochastic Processes Covering Multiple Length Scales
Zhang J, Creamer A, Xie K, Tang J, Salter L, Wojciechowski JP, Stevens MM
January 2025 | Journal article | Nature Communications | Read
Tissue-Specific Modulation of CRISPR Activity by miRNA-Sensing Guide RNAs
Garcia-Guerra A, Sathyaprakash C, de Jong OG, Lim WF, Vader P, El Andaloussi S, Bath J, Reine J, Aoki Y, Turberfield AJ, Wood MJA, Rinaldi C
January 2025 | Journal article | Nucleic Acids Research | Read
UnidecNMR: Automatic Peak Detection for NMR Spectra in 1-4 Dimensions
Buchanan C, Karunanithy G, Tkachenko O, Barber M, Marty MT, Nott TJ, Redfield C, Baldwin AJ
January 2025 | Journal article | Nature Communications | Read
Structural and Functional Glycosylation of the Abdala COVID-19 Vaccine
Burnap SA, Calvaresi V, Cabrera G, Pousa S, Limonta M, Ramos Y, González LJ, Harvey DJ, Struwe WB
January 2025 | Journal article | Glycobiology | Read
Enhanced Restoration of Visual Code After Targeting on Bipolar Cells Compared to Retinal Ganglion Cells with Optogenetic Therapy
Rodgers J, Hughes S, Ebrahimi AS, Allen AE, Storchi R, Lindner M, Peirson SN, Badea TC, Hankins MW, Lucas RJ
January 2025 | Journal article | Molecular Therapy | Read
Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel
Phan LX, Owji AP, Yang T, Crain J, Sansom MSP, Tucker SJ
January 2025 | Journal article | Journal of Chemical Theory and Computation | Read
Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers
Rowland HA, Miller G, Liu Q, Li S, Sharp NR, Ng B, Wei T, Arunasalam K, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Kocagoncu E, Lawson J, Malhotra P, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Zetterberg H, Cader MZ, Wade-Martins R, Lovestone S, Nevado-Holgado A, Kormilitzin A, Buckley NJ
December 2024 | Journal article | Stem Cells | Read
Safety and Efficacy of the Blood-Stage Malaria Vaccine RH5.1/Matrix-M in Burkina Faso: Interim Results of a Double-blind, Randomised, Controlled, Phase 2b Trial in Children
Natama HM, Salkeld J, Somé A, Soremekun S, Diallo S, Traoré O, Rouamba T, Ouédraogo F, Ouédraogo E, Daboné KCS, Koné NA, Compaoré ZMJ, Kafando M, Bonko MDA, Konaté F, Sorgho H, Nielsen CM, Pipini D, Diouf A, King LDW, Shaligram U, Long CA, Cho JS, Lawrie AM, Skinner K, Roberts R, Miura K, Bradley J, Silk SE, Draper SJ, Tinto H, Minassian AM
December 2024 | Journal article | The Lancet Infectious Diseases | Read
Unlocking Intracellular Protein Delivery by Harnessing Polymersomes Synthesized at Microliter Volumes using Photo-PISA
Thanapongpibul C, Rifaie-Graham O, Ojansivu M, Najer A, Kim H, Bakker SE, Chami M, Peeler DJ, Liu C, Yeow J, Stevens MM
December 2024 | Journal article | Advanced Materials | Read
Structure and Mechanism of the Zorya Anti-Phage Defense System
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
December 2024 | Journal article | Nature | Read
Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan Receptor GPR6 Implicated in Parkinson's Disease
Barekatain M, Johansson LC, Lam JH, Chang H, Sadybekov AV, Han GW, Russo J, Bliesath J, Brice NL, Carlton MBL, Saikatendu KS, Sun H, Murphy ST, Monenschein H, Schiffer HH, Popov P, Lutomski CA, Robinson CV, Liu ZJ, Hua T, Katritch V, Cherezov V
December 2024 | Journal article | Science Signaling | Read
Transfer Learning Bayesian Optimization for Competitor DNA Molecule Design for Use in Diagnostic Assays
Sedgwick R, Goertz JP, Stevens MM, Misener R, van der Wilk M
December 2024 | Journal article | Biotechnology and Bioengineering | Read
Investigating the Role of Elastin and Extracellular Matrix Damage in Cardiovascular Calcification
Radvar E, Mehta K, D'Ambrosio A, Mastroianni G, Al-Jawad M, Stevens MM, Mata A, Elsharkawy S
December 2024 | Journal article | Journal of Structural Biology | Read
Molecular Tags for Electron Cryo-Tomography
Silvester E, Baker LA
December 2024 | Journal article | Emerging Topics in Life Sciences | Read
Rhythmic Liver Drives Feeding Behavior
Martinez-Sanchez N, Ray D
November 2024 | Journal article | Science | Read
The PIK3CA Gene and its Pivotal Role in Tumor Tropism of Triple-Negative Breast Cancer
Mallick S, Duttaroy AK, Dutta S
November 2024 | Journal article | Science Direct | Read
How Clavulanic Acid Inhibits Serine β-Lactamases
Lang PA, de Munnik M, Oluwole AO, Claridge TDW, Robinson CV, Brem J, Schofield CJ
November 2024 | Journal article | ChemBioChem | Read
Hyperspectral Unmixing for Raman Spectroscopy via Physics-Constrained Autoencoders
Georgiev D, Fernández-Galiana Á, Vilms Pedersen S, Papadopoulos G, Xie R, Stevens MM, Barahona M
November 2024 | Journal article | PNAS | Read
Non-Invasive In Vivo Sensing of Bacterial Implant Infection Using Catalytically-Optimised Gold Nanocluster-Loaded Liposomes for Urinary Readout
Chen K, Najer A, Charchar P, Saunders C, Thanapongpibul C, Klöckner A, Chami M, Peeler DJ, Silva I, Panariello L, Karu K, Loynachan CN, Frenette LC, Potter M, Tregoning JS, Parkin IP, Edwards AM, Clarke TB, Yarovsky I, Stevens MM
November 2024 | Journal article | Nature Communications | Read
Atomically Resolved Imaging of the Conformations and Adsorption Geometries of Individual β-cyclodextrins with Non-Contact AFM
Grabarics M, Mallada B, Edalatmanesh S, Jiménez-Martín A, Pykal M, Ondráček M, Kührová P, Struwe WB, Banáš P, Rauschenbach S, Jelínek P, de la Torre B
November 2024 | Journal article | Nature Communications | Read
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers
Dellar ER, Vendrell I, Amein B, Lester DG, Edmond EC, Yoganathan K, Dharmadasa T, Sogorb-Esteve A, Fischer R, Talbot K, Rohrer JD, Turner MR, Thompson AG
November 2024 | Journal article | Annals of Neurology | Read
Author Correction: Location and Function of TDP-43 in Platelets, Alterations in Neurodegenerative Diseases and Arising Considerations for Current Plasma Biobank Protocols
Luthi-Carter R, Cappelli S, Le Roux-Bourdieu M, Tentillier N, Quinn JP, Petrozziello T, Gopalakrishnan L, Sethi P, Choudhary H, Bartolini G, Gebara E, Stuani C, Font L, An J, Ortega V, Sage J, Kosa E, Trombetta BA, Simeone R, Seredenina T, Afroz T, Berry JD, Arnold SE, Carlyle BC, Adolfsson O, Sadri-Vakili G, Buratti E, Bowser R, Agbas A
November 2024 | Journal article | Scientific Reports | Read
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation
Pérez de la Lastra Aranda C, Tosat-Bitrián C, Porras G, Dafinca R, Muñoz-Torrero D, Talbot K, Martín-Requero Á, Martínez A, Palomo V
November 2024 | Journal article | ACS Chemical Neuroscience | Read
Bioactive Coatings on 3D Printed Scaffolds for Bone Regeneration: Use of Laponite® to Deliver BMP-2 in an Ovine Femoral Condyle Defect Model
Marshall KM, McLaren JS, Wojciechowski JP, Callens SJP, Echalier C, Kanczler JM, Rose FRAJ, Stevens MM, Dawson JI, Oreffo ROC
November 2024 | Journal article | Science Direct | Read
Architecture-Driven Quantitative Nanoscopy Maps Cytoskeleton Remodeling
Liu W, Yao Y, Meng J, Qian S, Han Y, Zhou L, Wang T, Chen Y, Chen L, Ye Z, Xu L, Zhang M, Qiu J, Han T, Liu X, Kuang C, Ding Z, Liu Z
October 2024 | Journal article | PNAS | Read
Structural Basis for Antibiotic Transport and Inhibition in PepT2
Parker JL, Deme JC, Lichtinger SM, Kuteyi G, Biggin PC, Lea SM, Newstead S
October 2024 | Journal article | Nature Communications | Read
Transfer Learning Bayesian Optimization for Competitor DNA Molecule Design for Use in Diagnostic Assays
Sedgwick R, Goertz JP, Stevens MM, Misener R, van der Wilk M
October 2024 | Journal article | Biotechnology and Bioengineering | Read
Hyperspectral Unmixing for Raman Spectroscopy via Physics-Constrained Autoencoders
Georgiev D, Fernández-Galiana Á, Vilms Pedersen S, Papadopoulos G, Xie R, Stevens MM, Barahona M
October 2024 | Journal article | PNAS | Read
Blood-Stage Malaria Vaccine Candidate RH5.1/Matrix-M in Healthy Tanzanian Adults and Children; An Open-Label, Non-Randomised, First-in-Human, Single-Centre, Phase 1b Trial
Silk SE, Kalinga WF, Salkeld J, Mtaka IM, Ahmed S, Milando F, Diouf A, Bundi CK, Balige N, Hassan O, Mkindi CG, Rwezaula S, Athumani T, Mswata S, Lilolime NS, Simon B, Msami H, Mohamed M, David DM, Mohammed L, Nyaulingo G, Mwalimu B, Juma O, Mwamlima TG, Sasamalo IA, Mkumbange RP, Kamage JJ, Barrett JR, King LDW, Hou MM, Pulido D, Carnrot C, Lawrie AM, Cowan RE, Nugent FL, Roberts R, Cho JS, Long CA, Nielsen CM, Miura K, Draper SJ, Olotu AI, Minassian AM
October 2024 | Journal article | Lancet Infectious Diseases | Read
Structure and Conformation Determine Gas-Phase Infrared Spectra of Detergents
Kirschbaum C, Greis K, Gewinner S, Schöllkopf W, Meijer G, von Helden G, Pagel K, Urner LH
October 2024 | Journal article | Chem Plus Chem | Read
A Bioorthogonal Precision Tool for Human N-Acetylglucosaminyltransferase V
Liu Y, Bineva-Todd G, Meek RW, Mazo L, Piniello B, Moroz O, Burnap SA, Begum N, Ohara A, Roustan C, Tomita S, Kjaer S, Polizzi K, Struwe WB, Rovira C, Davies GJ, Schumann B
October 2024 | Journal article | Journal of the American Chemical Society | Read
Oligomerization-Driven Avidity Correlates with SARS-CoV-2 Cellular Binding and Inhibition
Asor R, Olerinyova A, Burnap SA, Kushwah MS, Soltermann F, Rudden LSP, Hensen M, Vasiljevic S, Brun J, Hill M, Chang L, Dejnirattisai W, Supasa P, Mongkolsapaya J, Zhou D, Stuart DI, Screaton GR, Degiacomi MT, Zitzmann N, Benesch JLP, Struwe WB, Kukura P
October 2024 | Journal article | PNAS | Read
Lipopeptide Antibiotics Disrupt Interactions of Undecaprenyl Phosphate with UptA
Oluwole AO, Kalmankar NV, Guida M, Bennett JL, Poce G, Bolla JR, Robinson CV
October 2024 | Journal article | PNAS | Read
Rational Structure-Guided Design of a Blood Stage Malaria Vaccine Immunogen Presenting a Single Epitope from PfRH5
Harrison TE, Alam N, Farrell B, Quinkert D, Lias AM, King LDW, Barfod LK, Draper SJ, Campeotto I, Higgins MK
October 2024 | Journal article | EMBO Molecular Medicine | Read
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation
Pérez de la Lastra Aranda C, Tosat-Bitrián C, Porras G, Dafinca R, Muñoz-Torrero D, Talbot K, Martín-Requero Á, Martínez A, Palomo V
October 2024 | Journal article | ACS Chemical Neuroscience | Read
Rapid Identification of Bacterial Isolates Using Microfluidic Adaptive Channels and Multiplexed Fluorescence Microscopy
Chatzimichail S, Turner P, Feehily C, Farrar A, Crook D, Andersson M, Oakley S, Barrett L, El Sayyed H, Kyropoulos J, Nellåker C, Stoesser N, Kapanidis AN
October 2024 | Journal article | Lab on a Chip | Read
Coupling and Activation of the β1 Adrenergic Receptor - The Role of the Third Intracellular Loop
Qiu X, Chao K, Song S, Wang YQ, Chen YA, Rouse SL, Yen HY, Robinson CV
October 2024 | Journal article | Journal of the American Chemical Society | Read
Unlocking Intracellular Protein Delivery by Harnessing Polymersomes Synthesized at Microliter Volumes using Photo-PISA
Thanapongpibul C, Rifaie-Graham O, Ojansivu M, Najer A, Kim H, Bakker SE, Chami M, Peeler DJ, Liu C, Yeow J, Stevens MM
October 2024 | Journal article | Advanced Materials | Read
Glial Cells Undergo Rapid Changes Following Acute Chemogenetic Manipulation of Cortical Layer 5 Projection Neurons
Vadisiute A, Meijer E, Therpurakal RN, Mueller M, Szabó F, Messore F, Jursenas A, Bredemeyer O, Krone LB, Mann E, Vyazovskiy V, Hoerder-Suabedissen A, Molnár Z
October 2024 | Journal article | Communications Biology | Read
Bioactive Coatings on 3D Printed Scaffolds for Bone Regeneration: Use of Laponite® to Deliver BMP-2 in an Ovine Femoral Condyle Defect Model
Marshall KM, McLaren JS, Wojciechowski JP, Callens SJP, Echalier C, Kanczler JM, Rose FRAJ, Stevens MM, Dawson JI, Oreffo ROC
October 2024 | Journal article | Biomaterials Advances | Read
Vaccine-Induced Human Monoclonal Antibodies to PfRH5 Show Broadly Neutralizing Activity Against P. falciparum Clinical Isolates
Thiam LG, McHugh K, Ba A, Li R, Guo Y, Pouye MN, Cisse A, Pipini D, Diallo F, Sene SD, Patel SD, Thiam A, Sadio BD, Mbengue A, Vigan-Womas I, Sheng Z, Shapiro L, Draper SJ, Bei AK
October 2024 | Journal article | NPJ Vaccines | Read
Dynactin-1 Mediates Rescue of Impaired Axonal Transport due to Reduced Mitochondrial Bioenergetics in Amyotrophic Lateral Sclerosis Motor Neurons
Dafinca R, Tosat-Bitrian C, Carroll E, Vahsen BF, Gilbert-Jaramillo J, Scaber J, Feneberg E, Johnson E, Talbot K
October 2024 | Journal article | Brain Communications | Read
Considerations of Growth Factor and Material Use in Bone Tissue Engineering Using Biodegradable Scaffolds in Vitro and in Vivo
Marshall KM, Wojciechowski JP, Jayawarna V, Hasan A, Echalier C, Øvrebø Ø, Yang T, Zhou K, Kanczler JM, Mata A, Salmeron-Sanchez M, Stevens MM, Oreffo ROC
October 2024 | Journal article | Scientific Reports | Read
The PIK3CA Gene and its Pivotal Role in Tumor Tropism of Triple-Negative Breast Cancer
Mallick S, Duttaroy AK, Dutta S
October 2024 | Journal article | Translational Oncology | Read
Physical-Property-Based Patterning: Simply Engineering Complex Tissues
Zlotnick HM, Stevens MM, Mauck RL
September 2024 | Journal article | Trends in Biotechnology | Read
Natural Malaria Infection Elicits Rare but Potent Neutralizing Antibodies to the Blood-Stage Antigen RH5
Wang LT, Cooper AJR, Farrell B, Miura K, Diouf A, Müller-Sienerth N, Crosnier C, Purser L, Kirtley PJ, Maciuszek M, Barrett JR, McHugh K, Ogwang R, Tucker C, Li S, Doumbo S, Doumtabe D, Pyo CW, Skinner J, Nielsen CM, Silk SE, Kayentao K, Ongoiba A, Zhao M, Nguyen DC, Lee FE, Minassian AM, Geraghty DE, Traore B, Seder RA, Wilder BK, Crompton PD, Wright GJ, Long CA, Draper SJ, Higgins MK, Tan J
September 2024 | Journal article | Cell | Read
Analysis Of the Diverse Antigenic Landscape of The Malaria Protein RH5 Identifies A Potent Vaccine-Induced Human Public Antibody Clonotype
Barrett JR, Pipini D, Wright ND, Cooper AJR, Gorini G, Quinkert D, Lias AM, Davies H, Rigby CA, Aleshnick M, Williams BG, Bradshaw WJ, Paterson NG, Martinson T, Kirtley P, Picard L, Wiggins CD, Donnellan FR, King LDW, Wang LT, Popplewell JF, Silk SE, de Ruiter Swain J, Skinner K, Kotraiah V, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Minassian AM, Lauffenburger DA, Miura K, Long CA, Wilder BK, Koekemoer L, Tan J, Nielsen CM, McHugh K, Draper SJ
September 2024 | Journal article | Cell | Read
Variant-Specific Effects of GBA1 Mutations on Dopaminergic Neuron Proteostasis
Onal G, Yalçın-Çakmaklı G, Özçelik CE, Boussaad I, Şeker UÖŞ, Fernandes HJR, Demir H, Krüger R, Elibol B, Dökmeci S, Salman MM
September 2024 | Journal article | Journal of Neurochemistry | Read
Light Sampling Behaviour Regulates Circadian Entrainment in Mice
Steel LCE, Tam SKE, Brown LA, Foster RG, Peirson SN
September 2024 | Journal article | BMC Biology | Read
Engineering Stress as a Motivation for Filamentous Virus Morphology
McMahon A, Vijayakrishnan S, El Sayyed H, Groves D, Conley MJ, Hutchinson E, Robb NC
September 2024 | Journal article | Biophysical Reports | Read
Blood-Stage Malaria Vaccine Candidate RH5.1/Matrix-M in Healthy Tanzanian Adults and Children; An Open-Label, Non-Randomised, First-in-Human, Single-Centre, Phase 1b Trial
Silk SE, Kalinga WF, Salkeld J, Mtaka IM, Ahmed S, Milando F, Diouf A, Bundi CK, Balige N, Hassan O, Mkindi CG, Rwezaula S, Athumani T, Mswata S, Lilolime NS, Simon B, Msami H, Mohamed M, David DM, Mohammed L, Nyaulingo G, Mwalimu B, Juma O, Mwamlima TG, Sasamalo IA, Mkumbange RP, Kamage JJ, Barrett JR, King LDW, Hou MM, Pulido D, Carnrot C, Lawrie AM, Cowan RE, Nugent FL, Roberts R, Cho JS, Long CA, Nielsen CM, Miura K, Draper SJ, Olotu AI, Minassian AM
September 2024 | Journal article | The Lancet Infectious Diseases | Read
A Bioorthogonal Precision Tool for Human N-Acetylglucosaminyltransferase V
Liu Y, Bineva-Todd G, Meek RW, Mazo L, Piniello B, Moroz O, Burnap SA, Begum N, Ohara A, Roustan C, Tomita S, Kjaer S, Polizzi K, Struwe WB, Rovira C, Davies GJ, Schumann B
September 2024 | Journal article | Journal of the American Chemical Society | Read
A Facile Method to Quantify Synthetic Peptide Concentrations on Biomaterials
Wojciechowski JP, Benge T, Chen K, Echalier C, Xie R, Stevens MM
September 2024 | Journal article | ACS Applied Materials & Interfaces | Read
Oligomerization-Driven Avidity Correlates with SARS-CoV-2 Cellular Binding and Inhibition
Asor R, Olerinyova A, Burnap SA, Kushwah MS, Soltermann F, Rudden LSP, Hensen M, Vasiljevic S, Brun J, Hill M, Chang L, Dejnirattisai W, Supasa P, Mongkolsapaya J, Zhou D, Stuart DI, Screaton GR, Degiacomi MT, Zitzmann N, Benesch JLP, Struwe WB, Kukura P
September 2024 | Journal article | PNAS | Read
Plug and Play Virus-like Particles for the Generation of Anti-toxin Antibodies
Edge RJ, Marriott AE, Stars EL, Patel RN, Wilkinson MC, King LDW, Slagboom J, Tan CH, Ratanabanangkoon K, Draper SJ, Ainsworth S
September 2024 | Journal article | Toxicon: X | Read
Rapid Identification of Bacterial Isolates Using Microfluidic Adaptive Channels and Multiplexed Fluorescence Microscopy
Chatzimichail S, Turner P, Feehily C, Farrar A, Crook D, Andersson M, Oakley S, Barrett L, El Sayyed H, Kyropoulos J, Nellåker C, Stoesser N, Kapanidis AN
September 2024 | Journal article | Lab on a Chip | Read
Rational Structure-Guided Design of a Blood Stage Malaria Vaccine Immunogen Presenting a Single Epitope from PfRH5
Harrison TE, Alam N, Farrell B, Quinkert D, Lias AM, King LDW, Barfod LK, Draper SJ, Campeotto I, Higgins MK
September 2024 | Journal article | EMBO Molecular Medicine | Read
Sensing the Structural and Conformational Properties of Single-Stranded Nucleic Acids Using Electrometry and Molecular Simulations
Walker-Gibbons R, Zhu X, Behjatian A, Bennett TJD, Krishnan M
September 2024 | Journal article | Scientific Reports | Read
Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro
Chen MS, Sun R, Wang R, Zuo Y, Zhou K, Kim J, Stevens MM
September 2024 | Journal article | Advanced Healthcare Materials | Read
Oscillatory-Quality of Sleep Spindles Links Brain State with Sleep Regulation and Function
Blanco-Duque C, Bond SA, Krone LB, Dufour JP, Gillen ECP, Purple RJ, Kahn MC, Bannerman DM, Mann EO, Achermann P, Olbrich E, Vyazovskiy VV
September 2024 | Journal article | Science Advances | Read
Ablation of Oligodendrogenesis in Adult Mice Alters Brain Microstructure and Activity Independently of Behavioral Deficits
Kaller MS, Lazari A, Feng Y, van der Toorn A, Rühling S, Thomas CW, Shimizu T, Bannerman D, Vyazovskiy V, Richardson WD, Sampaio-Baptista C, Johansen-Berg H
September 2024 | Journal article | Glia | Read
Author Correction: Covalent Penicillin-protein Conjugates Elicit Anti-drug Antibodies that are Clonally and Functionally Restricted
Deimel LP, Moynié L, Sun G, Lewis V, Turner A, Buchanan CJ, Burnap SA, Kutuzov M, Kobras CM, Demyanenko Y, Mohammed S, Stracy M, Struwe WB, Baldwin AJ, Naismith J, Davis BG, Sattentau QJ
September 2024 | Journal article | Nature Communications | Read
Molecular Basis of TMED9 Oligomerization and Entrapment of Misfolded Protein Cargo in the Early Secretory Pathway
Xiao L, Pi X, Goss AC, El-Baba T, Ehrmann JF, Grinkevich E, Bazua-Valenti S, Padovano V, Alper SL, Carey D, Udeshi ND, Carr SA, Pablo JL, Robinson CV, Greka A, Wu H
September 2024 | Journal article | Science Advances | Read
Location and Function of TDP-43 in Platelets, Alterations in Neurodegenerative Diseases and Arising Considerations for Current Plasma Biobank Protocols
Luthi-Carter R, Cappelli S, Le Roux-Bourdieu M, Tentillier N, Quinn JP, Petrozziello T, Gopalakrishnan L, Sethi P, Choudhary H, Bartolini G, Gebara E, Stuani C, Font L, An J, Ortega V, Sage J, Kosa E, Trombetta BA, Simeone R, Seredenina T, Afroz T, Berry JD, Arnold SE, Carlyle BC, Adolfsson O, Sadri-Vakili G, Buratti E, Bowser R, Agbas A
September 2024 | Journal article | Scientific Reports | Read
Practical Advice on Measuring and Applying Light for Laboratory Mammals.
Lucas RJ, Peirson SN
August 2024 | Journal article | Journal of Biological Rhythms | Read
Native MS-guided Lipidomics to Define Endogenous Lipid Microenvironments of Eukaryotic Receptors and Transporters
Wu D, Tang H, Qiu X, Song S, Chen S, Robinson CV
August 2024 | Journal article | Nature Protocols | Read
Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning
Kratochvíl J, Asor R, Helmi S, Struwe WB, Kukura P
August 2024 | Journal article | Nano Letters | Read
Biological Effects of Sodium Phenylbutyrate and Taurursodiol in Alzheimer's Disease
Knowlton N, Williams VJ, Burns JM, Crane M, McManus AJ, Vaishnavi SN, Arvanitakis Z, Neugroschl J, Bell K, Trombetta BA, Carlyle BC, Kivisäkk P, Dodge HH, Tanzi RE, Yeramian PD, Leslie K
August 2024 | Journal article | Alzheimer’s Association | Read
Covalent Penicillin-protein Conjugates Elicit Anti-drug Antibodies that are Clonally and Functionally Restricted
Deimel LP, Moynié L, Sun G, Lewis V, Turner A, Buchanan CJ, Burnap SA, Kutuzov M, Kobras CM, Demyaneko Y, Mohammed S, Stracy M, Struwe WB, Baldwin AJ, Naismith J, Davis BG, Sattentau QJ
August 2024 | Journal article | Nature Communications | Read
Infection Inspection: Using the Power of Citizen Science for Image-based Prediction of Antibiotic Resistance in Escherichia Coli Treated with Ciprofloxacin
Farrar A, Feehily C, Turner P, Zagajewski A, Chatzimichail S, Crook D, Andersson M, Oakley S, Barrett L, El Sayyed H, Fowler PW, Nellåker C, Kapanidis AN, Stoesser N
August 2024 | Journal article | Scientific Reports | Read
ATAXIN-2 Intermediate-length Polyglutamine Expansions Elicit ALS-associated Metabolic and Immune Phenotypes
Vieira de Sá R, Sudria-Lopez E, Cañizares Luna M, Harschnitz O, van den Heuvel DMA, Kling S, Vonk D, Westeneng HJ, Karst H, Bloemenkamp L, Varderidou-Minasian S, Schlegel DK, Mars M, Broekhoven MH, van Kronenburg NCH, Adolfs Y, Vangoor VR, de Jongh R, Ljubikj T, Peeters L, Seeler S, Mocholi E, Basak O, Gordon D, Giuliani F, Verhoeff T, Korsten G, Calafat Pla T, Venø MT, Kjems J, Talbot K, van Es MA, Veldink JH, van den Berg LH, Zelina P, Pasterkamp RJ
August 2024 | Journal article | Nature communications | Read
Using Matrix Assisted Laser Desorption Ionisation Mass Spectrometry Combined with Machine Learning for Vaccine Authenticity Screening
Clarke R, Bharucha T, Arman BY, Gangadharan B, Gomez Fernandez L, Mosca S, Lin Q, Van Assche K, Stokes R, Dunachie S, Deats M, Merchant HA, Caillet C, Walsby-Tickle J, Probert F, Matousek P, Newton PN, Zitzmann N, McCullagh JSO
August 2024 | Journal article | Npj Vaccines | Read
Analysis of the Diverse Antigenic Landscape of the Malaria Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype
Barrett JR, Pipini D, Wright ND, Cooper AJR, Gorini G, Quinkert D, Lias AM, Davies H, Rigby CA, Aleshnick M, Williams BG, Bradshaw WJ, Paterson NG, Martinson T, Kirtley P, Picard L, Wiggins CD, Donnellan FR, King LDW, Wang LT, Popplewell JF, Silk SE, de Ruiter Swain J, Skinner K, Kotraiah V, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Minassian AM, Lauffenburger DA, Miura K, Long CA, Wilder BK, Koekemoer L, Tan J, Nielsen CM, McHugh K, Draper SJ
July 2024 | Journal article | Cell | Read
Natural Malaria Infection Elicits Rare but Potent Neutralizing Antibodies to the Blood-stage Antigen RH5
Wang LT, Cooper AJR, Farrell B, Miura K, Diouf A, Müller-Sienerth N, Crosnier C, Purser L, Kirtley PJ, Maciuszek M, Barrett JR, McHugh K, Ogwang R, Tucker C, Li S, Doumbo S, Doumtabe D, Pyo CW, Skinner J, Nielsen CM, Silk SE, Kayentao K, Ongoiba A, Zhao M, Nguyen DC, Lee FE, Minassian AM, Geraghty DE, Traore B, Seder RA, Wilder BK, Crompton PD, Wright GJ, Long CA, Draper SJ, Higgins MK, Tan J
July 2024 | Journal article | Cell | Read
Ablation of Oligodendrogenesis in Adult Mice Alters Brain Microstructure and Activity Independently of Behavioral Deficits
Kaller MS, Lazari A, Feng Y, van der Toorn A, Rühling S, Thomas CW, Shimizu T, Bannerman D, Vyazovskiy V, Richardson WD, Sampaio-Baptista C, Johansen-Berg H
July 2024 | Journal article | Glia | Read
Preclinical Development of a Stabilized RH5 Virus-like Particle Vaccine that Induces Improved Antimalarial Antibodies
King LDW, Pulido D, Barrett JR, Davies H, Quinkert D, Lias AM, Silk SE, Pattinson DJ, Diouf A, Williams BG, McHugh K, Rodrigues A, Rigby CA, Strazza V, Suurbaar J, Rees-Spear C, Dabbs RA, Ishizuka AS, Zhou Y, Gupta G, Jin J, Li Y, Carnrot C, Minassian AM, Campeotto I, Fleishman SJ, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Long CA, Miura K, Ashfield R, Skinner K, Howarth MR, Biswas S, Draper SJ
July 2024 | Journal article | Cell Reports Medicine | Read
A Chemical Reaction Network Drives Complex Population Dynamics in Oscillating Self-Reproducing Vesicles
Zhang Z, Howlett MG, Silvester E, Kukura P, Fletcher SP
July 2024 | Journal article | Journal of the American Chemical Society | Read
The Mechanism of Mammalian Proton-Coupled Peptide Transporters
Lichtinger SM, Parker JL, Newstead S, Biggin PC
July 2024 | Journal article | ELife | Read
Recent Insights from Human Induced Pluripotent Stem Cell Models into the Role of Microglia in Amyotrophic Lateral Sclerosis
Nikel LM, Talbot K, Vahsen BF
July 2024 | Journal article | BioEssays | Read
Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning
Kratochvíl J, Asor R, Helmi S, Struwe WB, Kukura P
July 2024 | Journal article | Nano Letters | Read
Molecular Basis for pH Sensing in the KDEL Trafficking Receptor
Wu Z, Smith K, Gerondopoulos A, Sobajima T, Parker JL, Barr FA, Newstead S, Biggin PC
July 2024 | Journal article | Structure | Read
Functional Diversity Among Cardiolipin Binding Sites on the Mitochondrial ADP/ATP Carrier
Senoo N, Chinthapalli DK, Baile MG, Golla VK, Saha B, Oluwole AO, Ogunbona OB, Saba JA, Munteanu T, Valdez Y, Whited K, Sheridan MS, Chorev D, Alder NN, May ER, Robinson CV, Claypool SM
July 2024 | Journal article | The EMBO Journal | Read
Astrocytes in Functional Recovery Following Central Nervous System Injuries
Alhadidi QM, Bahader GA, Arvola O, Kitchen P, Shah ZA, Salman MM
July 2024 | Journal article | The Journal of Physiology | Read
Methods to Estimate Body Temperature and Energy Expenditure Dynamics in Fed and Fasted Laboratory Mice: Effects of Sleep Deprivation and Light Exposure
van der Vinne V, McKillop LE, Wilcox SL, Cantley J, Peirson SN, Swoap SJ, Vyazovskiy VV
June 2024 | Journal article | Journal of Comparative Physiology B | Read
Phage Defence System CBASS is Regulated by a Prokaryotic E2 Enzyme that Imitates the Ubiquitin Pathway
Yan Y, Xiao J, Huang F, Xian W, Yu B, Cheng R, Wu H, Lu X, Wang X, Huang W, Li J, Oyejobi GK, Robinson CV, Wu H, Wu D, Liu X, Wang L, Zhu B
June 2024 | Journal article | Nature Microbiology | Read
ROS-Dependent S-palmitoylation Activates Cleaved and Intact Gasdermin D
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H
June 2024 | Journal article | Nature | Read
A Chemical Reaction Network Drives Complex Population Dynamics in Oscillating Self-Reproducing Vesicles
Zhang Z, Howlett MG, Silvester E, Kukura P, Fletcher SP
June 2024 | Journal article | Journal of the American Chemical Society | Read
Blood-stage Malaria Vaccine Candidate RH5.1/Matrix-M in Healthy Tanzanian Adults and Children; an Open-label, Non-randomised, First-in-human, Single-centre, Phase 1b Trial
Silk SE, Kalinga WF, Salkeld J, Mtaka IM, Ahmed S, Milando F, Diouf A, Bundi CK, Balige N, Hassan O, Mkindi CG, Rwezaula S, Athumani T, Mswata S, Lilolime NS, Simon B, Msami H, Mohamed M, David DM, Mohammed L, Nyaulingo G, Mwalimu B, Juma O, Mwamlima TG, Sasamalo IA, Mkumbange RP, Kamage JJ, Barrett JR, King LDW, Hou MM, Pulido D, Carnrot C, Lawrie AM, Cowan RE, Nugent FL, Roberts R, Cho JS, Long CA, Nielsen CM, Miura K, Draper SJ, Olotu AI, Minassian AM
June 2024 | Journal article | The Lancet Infectious Diseases | Read
Development of an Improved Blood-stage Malaria Vaccine Targeting the Essential RH5-CyRPA-RIPR Invasion Complex
Williams BG, King LDW, Pulido D, Quinkert D, Lias AM, Silk SE, Ragotte RJ, Davies H, Barrett JR, McHugh K, Rigby CA, Alanine DGW, Barfod L, Shea MW, Cowley LA, Dabbs RA, Pattinson DJ, Douglas AD, Lyth OR, Illingworth JJ, Jin J, Carnrot C, Kotraiah V, Christen JM, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Skinner K, Miura K, Long CA, Higgins MK, Draper SJ
June 2024 | Journal article | Nature Communications | Read
Functional Diversity Among Cardiolipin Binding Sites on the Mitochondrial ADP/ATP Carrier
Senoo N, Chinthapalli DK, Baile MG, Golla VK, Saha B, Oluwole AO, Ogunbona OB, Saba JA, Munteanu T, Valdez Y, Whited K, Sheridan MS, Chorev D, Alder NN, May ER, Robinson CV, Claypool SM
June 2024 | Journal article | The EMBO Journal | Read
Cellular and Axonal Transport Phenotypes due to the C9ORF72 HRE in iPSC Motor and Sensory Neurons
Scaber J, Thomas-Wright I, Clark AJ, Xu Y, Vahsen BF, Carcolé M, Dafinca R, Farrimond L, Isaacs AM, Bennett DL, Talbot K
June 2024 | Journal article | Stem Cell Reports | Read
Body Weight Modulates the Impact of Oxytocin on Chronic Cold-immobilization Stress Response
Önal D, Korkmaz H, Önal G, Pehlivanoğlu B
June 2024 | Journal article | Peptites | Read
Structural Basis for IL-33 Recognition and its Antagonism by the Helminth Effector Protein HpARI2
Jamwal A, Colomb F, McSorley HJ, Higgins MK
June 2024 | Journal article | Nature Communications | Read
Plasma VEGFA and PGF Impact Longitudinal Tau and Cognition in Preclinical Alzheimer's Disease
Yang HS, Yau WW, Carlyle BC, Trombetta BA, Zhang C, Shirzadi Z, Schultz AP, Pruzin JJ, Fitzpatrick CD, Kirn DR, Rabin JS, Buckley RF, Hohman TJ, Rentz DM, Tanzi RE, Johnson KA, Sperling RA, Arnold SE, Chhatwal JP
June 2024 | Journal article | Brain | Read
Paired Plasma Lipidomics and Proteomics Analysis in the Conversion from Mild Cognitive Impairment to Alzheimer's Disease
Gómez-Pascual A, Naccache T, Xu J, Hooshmand K, Wretlind A, Gabrielli M, Lombardo MT, Shi L, Buckley NJ, Tijms BM, Vos SJB, Ten Kate M, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Streffer J, Barkhof F, Zetterberg H, Visser PJ, Lovestone S, Bertram L, Nevado-Holgado AJ, Gualerzi A, Picciolini S, Proitsi P, Verderio C, Botía JA, Legido-Quigley C
May 2024 | Journal article | Computers in Biology and Medicine | Read
Ultrasonic Vocalisation Rate Tracks the Diurnal Pattern of Activity in Winter Phenotype Djungarian Hamsters (Phodopus sungorus)
Harding CD, Walker KMM, Hackett TD, Herwig A, Peirson SN, Vyazovskiy VV
May 2024 | Journal article | Journal of Comparative Physiology B | Read
Extracellular Modulation of TREK-2 Activity with Nanobodies Provides Insight into the Mechanisms of K2P Channel Regulation
Rödström KEJ, Cloake A, Sörmann J, Baronina A, Smith KHM, Pike ACW, Ang J, Proks P, Schewe M, Holland-Kaye I, Bushell SR, Elliott J, Pardon E, Baukrowitz T, Owens RJ, Newstead S, Steyaert J, Carpenter EP, Tucker SJ
May 2024 | Journal article | Nature Communications | Read
Evaluation of the Precision of the Plasmodium Knowlesi Growth Inhibition Assay for Plasmodium Vivax Duffy-binding Protein-based Malaria Vaccine Development
Mertens JE, Rigby CA, Bardelli M, Quinkert D, Hou MM, Diouf A, Silk SE, Chitnis CE, Minassian AM, Moon RW, Long CA, Draper SJ, Miura K
May 2024 | Journal article | Vaccine | Read
An ALS-associated Mutation Dysregulates Microglia-derived Extracellular MicroRNAs in a Sex-specific Manner
Christoforidou E, Moody L, Joilin G, Simoes FA, Gordon D, Talbot K, Hafezparast M
May 2024 | Journal article | Disease Models and Mechanisms | Read
BERNN: Enhancing Classification of Liquid Chromatography Mass Spectrometry Data with Batch Effect Removal Neural Networks
Pelletier SJ, Leclercq M, Roux-Dalvai F, de Geus MB, Leslie S, Wang W, Lam TT, Nairn AC, Arnold SE, Carlyle BC, Precioso F, Droit A
May 2024 | Journal article | Nature Communications | Read
Recent Insights from Human Induced Pluripotent Stem Cell Models into the Role of Microglia in Amyotrophic Lateral Sclerosis
Nikel LM, Talbot K, Vahsen BF
May 2024 | Journal article | BioEssays | Read
Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro
Chen MS, Sun R, Wang R, Zuo Y, Zhou K, Kim J, Stevens MM
May 2024 | Journal article | Advanced Healthcare Materials | Read
4D Multimaterial Printing of Soft Actuators with Spatial and Temporal Control
Zhou K, Sun R, Wojciechowski JP, Wang R, Yeow J, Zuo Y, Song X, Wang C, Shao Y, Stevens MM
May 2024 | Journal article | Advanced Materials | Read
The Complete Assembly of Human LAT1-4F2hc Complex Provides Insights into its Regulation, Function and Localisation
Wu D, Yan R, Song S, Swansiger AK, Li Y, Prell JS, Zhou Q, Robinson CV
May 2024 | Journal article | Nature Communications | Read
Methods to Estimate Body Temperature and Energy Expenditure Dynamics in Fed and Fasted Laboratory Mice: Effects of Sleep Deprivation and Light Exposure
van der Vinne V, McKillop LE, Wilcox SL, Cantley J, Peirson SN, Swoap SJ, Vyazovskiy VV
April 2024 | Journal article | Journal of Comparative Physiology | Read
3,4-Ethylenedioxythiophene Hydrogels: Relating Structure and Charge Transport in Supramolecular Gels
Salter LCB, Wojciechowski JP, McLean B, Charchar P, Barnes PRF, Creamer A, Doutch J, Barriga HMG, Holme MN, Yarovsky I, Stevens MM
April 2024 | Journal article | Chemistry of Materials | Read
Phage Defence System CBASS is Regulated by a Prokaryotic E2 Enzyme that Imitates the Ubiquitin Pathway
Yan Y, Xiao J, Huang F, Xian W, Yu B, Cheng R, Wu H, Lu X, Wang X, Huang W, Li J, Oyejobi GK, Robinson CV, Wu H, Wu D, Liu X, Wang L, Zhu B
April 2024 | Journal article | Nature Microbiology | Read
Variant-specific Effects of GBA1 Mutations on Dopaminergic Neuron Proteostasis
Onal G, Yalçın-Çakmaklı G, Özçelik CE, Boussaad I, Şeker UÖŞ, Fernandes HJR, Demir H, Krüger R, Elibol B, Dökmeci S, Salman MM
April 2024 | Journal article | Journal of Neurochemistry | Read
A Charge-dependent Long-ranged Force Drives Tailored Assembly of Matter in Solution
Wang S, Walker-Gibbons R, Watkins B, Flynn M, Krishnan M
April 2024 | Journal article | Nature Nanotechnology | Read
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins
Urner LH, Fiorentino F, Shutin D, Sauer JB, Agasid MT, El-Baba TJ, Bolla JR, Stansfeld PJ, Robinson CV
April 2024 | Journal article | Journal of the American Chemical Society | Read
Molecular Mechanism of Complement Inhibition by the Trypanosome Receptor ISG65
Cook AD, Carrington M, Higgins MK
April 2024 | Journal article | Elife | Read
Emergence of Fractal Geometries in the Evolution of a Metabolic Enzyme
Sendker FL, Lo YK, Heimerl T, Bohn S, Persson LJ, Mais CN, Sadowska W, Paczia N, Nußbaum E, Del Carmen Sánchez Olmos M, Forchhammer K, Schindler D, Erb TJ, Benesch JLP, Marklund EG, Bange G, Schuller JM, Hochberg GKA
April 2024 | Journal article | Nature | Read
Molecular Basis for pH Sensing in the KDEL Trafficking Receptor
Wu Z, Smith K, Gerondopoulos A, Sobajima T, Parker JL, Barr FA, Newstead S, Biggin PC
April 2024 | Journal article | Structure | Read
Physical-property-based Patterning: Simply Engineering Complex Tissues
Zlotnick HM, Stevens MM, Mauck RL
April 2024 | Journal article | Trends in Biotechnology | Read
Phospholipids Differentially Regulate Ca2+ Binding to Synaptotagmin-1
Lawrence SAS, Kirschbaum C, Bennett JL, Lutomski CA, El-Baba TJ, Robinson CV
April 2024 | Journal article | ACS Chemical Biology | Read
CRISPRi: A Way to Integrate iPSC-derived Neuronal Models
Franks SNJ, Heon-Roberts R, Ryan BJ
April 2024 | Journal article | Biochemical Society Transactions | Read
Microneedle-mediated Nanomedicine to Enhance Therapeutic and Diagnostic Efficacy
Zuo Y, Sun R, Del Piccolo N, Stevens MM
April 2024 | Journal article | Nano Convergence | Read
Future Opportunities in Solute Carrier Structural Biology
Newstead S
April 2024 | Journal article | Nature Structural & Molecular Biology | Read
ROS-dependent S-palmitoylation Activates Cleaved and Intact Gasdermin D
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H
April 2024 | Journal article | Nature | Read
Single-protein Optical Holography
Thiele, J.C., Pfitzner, E. & Kukura, P
March 2024 | Journal article | Nature Photonics | Read
Recommendations for Measuring and Standardizing Light for Laboratory Mammals to Improve Welfare and Reproducibility in Animal Research
Lucas RJ, Allen AE, Brainard GC, Brown TM, Dauchy RT, Didikoglu A, Do MTH, Gaskill BN, Hattar S, Hawkins P, Hut RA, McDowell RJ, Nelson RJ, Prins JB, Schmidt TM, Takahashi JS, Verma V, Voikar V, Wells S, Peirson SN
March 2024 | Journal article | PLOS Biology | Read
A Charge-dependent Long-ranged Force Drives Tailored Assembly of Matter in Solution
Wang S, Walker-Gibbons R, Watkins B, Flynn M, Krishnan M
March 2024 | Journal article | Nature Nanotechnology | Read
Interrogation of the Human Cortical Peptidome Uncovers Cell-type Specific Signatures of Cognitive Resilience Against Alzheimer's Disease
Morgan GR, Carlyle BC
March 2024 | Journal article | Scientific Reports | Read
Myosin-5 Caries its Step Length to Carry Cargo Straight Along the Irregular F-actin Track
Fineberg A, Takagi Y, Thirumurugan K, Andrecka J, Billington N, Young G, Cole D, Burgess SA, Curd AP, Hammer JA, Sellers JR, Kukura P, Knight PJ
March 2024 | Journal article | PNAS | Read
Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response
Önal D, Korkmaz H, Önal G, Pehlivanoğlu B
March 2024 | Journal article | Peptides | Read
Real-Time Biosynthetic Reaction Monitoring Informs the Mechanism of Action of Antibiotics
Oluwole AO, Hernández-Rocamora VM, Cao Y, Li X, Vollmer W, Robinson CV, Bolla JR
March 2024 | Journal article | Journal of the American Chemical Society | Read
Repurposing Rapid Diagnostic Tests to Detect Falsified Vaccines in Supply Chains
Bharucha T, Gangadharan B, Clarke R, Fernandez LG, Arman BY, Walsby-Tickle J, Deats M, Mosca S, Lin Q, Stokes R, Dunachie S, Merchant HA, Dubot-Pérès A, Caillet C, McCullagh J, Matousek P, Zitzmann N, Newton PN
March 2024 | Journal article | Vaccine | Read
A Single Nuclear Transcriptomic Characterisation of Mechanisms Responsible for Impaired Angiogenesis and Blood-brain Barrier Function in Alzheimer's Disease
Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith AM, Willumsen N, Cheung TKD, Rokicki MJ, Chau V, Ifie E, Khozoie C, Ansorge O, Yang X, Jenkyns MH, Davey K, McGarry A, Muirhead RCJ, Debette S, Jackson JS, Montagne A, Owen DR, Miners JS, Love S, Webber C, Cader MZ, Matthews PM
March 2024 | Journal article | Nature Communications | Read
Ion Mobility-tandem Mass Spectrometry of Mucin-type O-glycans
Bechtella L, Chunsheng J, Fentker K, Ertürk GR, Safferthal M, Polewski Ł, Götze M, Graeber SY, Vos GM, Struwe WB, Mall MA, Mertins P, Karlsson NG, Pagel K
March 2024 | Journal article | Nature Communications | Read
CRISPRi: A Way to Integrate iPSC-derived Neuronal Models
Franks SNJ, Heon-Roberts R, Ryan BJ
March 2024 | Journal article | Biochemical Society Transactions | Read
Single-cell Spatial Transcriptomic and Translatomic Profiling of Dopaminergic Neurons in Health, Aging, and Disease
Kilfeather P, Khoo JH, Wagner K, Liang H, Caiazza MC, An Y, Zhang X, Chen X, Connor-Robson N, Shang Z, Wade-Martins R
March 2024 | Journal article | Cell Reports | Read
Coarse-grained Modeling of DNA-RNA Hybrids.
Ratajczyk EJ, Šulc P, Turberfield AJ, Doye JPK, Louis AA
March 2024 | Journal article | The Journal of Chemical Physics | Read
Plasma VEGFA and PGF Impact Longitudinal Tau and Cognition in Preclinical Alzheimer's Disease
Yang HS, Yau WW, Carlyle BC, Trombetta BA, Zhang C, Shirzadi Z, Schultz AP, Pruzin JJ, Fitzpatrick CD, Kirn DR, Rabin JS, Buckley RF, Hohman TJ, Rentz DM, Tanzi RE, Johnson KA, Sperling RA, Arnold SE, Chhatwal JP
February 2024 | Journal article | Brain | Read
Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis
Dellar ER, Vendrell I, Talbot K, Kessler BM, Fischer R, Turner MR, Thompson AG
February 2024 | Journal article | Journal of Neurochemistry | Read
Cryo-EM of Soft-landed β-galactosidase: Gas-phase and Native Structures are Remarkably Similar
Esser TK, Böhning J, Önür A, Chinthapalli DK, Eriksson L, Grabarics M, Fremdling P, Konijnenberg A, Makarov A, Botman A, Peter C, Benesch JLP, Robinson CV, Gault J, Baker L, Bharat TAM, Rauschenbach S
February 2024 | Journal article | Science Advances | Read
Single-cell Spatial Transcriptomic and Translatomic Profiling of Dopaminergic Neurons in Health, Aging, and Disease
Kilfeather P, Khoo JH, Wagner K, Liang H, Caiazza MC, An Y, Zhang X, Chen X, Connor-Robson N, Shang Z, Wade-Martins R
February 2024 | Journal article | Cell Reports | Read
A New Architecture for DNA-Templated Synthesis in Which Abasic Sites Protect Reactants from Degradation
Frommer J, Oppenheimer R, Allott BM, Núñez-Pertíñez S, Wilks TR, Cox LR, Bath J, O'Reilly RK, Turberfield AJ
February 2024 | Journal article | Angewandte Chemie | Read
Mechanisms of Aquaporin-4 Vesicular Trafficking in Mammalian Cells
Markou A, Kitchen P, Aldabbagh A, Repici M, Salman MM, Bill RM, Balklava Z
February 2024 | Journal article | Journal of Neurochemistry | Read
Constitutive Activation Mechanism of a Class C GPCR
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
February 2024 | Journal article | Nature Structural & Molecular Biology | Read
Repurposing Rapid Diagnostic Tests to Detect Falsified Vaccines in Supply Chains
Bharucha T, Gangadharan B, Clarke R, Fernandez LG, Arman BY, Walsby-Tickle J, Deats M, Mosca S, Lin Q, Stokes R, Dunachie S, Merchant HA, Dubot-Pérès A, Caillet C, McCullagh J, Matousek P, Zitzmann N, Newton PN
February 2024 | Journal article | Science Direct | Read
Magnetically Driven Formation of 3D Freestanding Soft Bioscaffolds
Xie R, Cao Y, Sun R, Wang R, Morgan A, Kim J, Callens SJP, Xie K, Zou J, Lin J, Zhou K, Lu X, Stevens MM
February 2024 | Journal article | Science Advances | Read
Tau Depletion in Human Neurons Mitigates Aβ-driven Toxicity
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R
February 2024 | Journal article | Molecular Psychiatry | Read
Neuro-immune Interactions in Health and Disease: Insights from FENS-Hertie 2022 Winter School
Binder LB, Rosa PB, de Sousa BM, Chagas LS, Dubljević O, Martineau FS, Mottarlini F, Castany S, Morton L, Krstanović F, Tassinari ID, Choconta JL, Pereira-Santos AR, Weinhard L, Pallegar PN, Vahsen BF, Lepiarz-Raba I, Compagnion AC, Lorente-Picón M
February 2024 | Journal article | European Journal of Neuroscience | Read
Measuring Protein-Protein Interactions and Quantifying Their Dissociation Constants with Mass Photometry
Kofinova Z, Karunanithy G, Ferreira AS, Struwe WB
January 2024 | Journal article | Current Protocols | Read
PvDBPII Elicits Multiple Antibody-mediated Mechanisms that Reduce Growth in a Plasmodium Vivax Challenge Trial
Martinez FJ, White M, Guillotte-Blisnick M, Huon C, Boucharlat A, Agou F, England P, Popovici J, Hou MM, Silk SE, Barrett JR, Nielsen CM, Reimer JM, Mukherjee P, Chauhan VS, Minassian AM, Draper SJ, Chitnis CE
January 2024 | Journal article | NPJ Vaccines | Read
From Structural Polymorphism to Structural Metamorphosis of the Coat Protein of Flexuous Filamentous Potato Virus Y
Kavčič L, Kežar A, Koritnik N, Žnidarič MT, Klobučar T, Vičič Ž, Merzel F, Holden E, Benesch JLP, Podobnik M
January 2024 | Journal article | Communications Chemistry | Read
Characterization of Membrane Protein Interactions by Peptidisc-mediated Mass Photometry
Young JW, Pfitzner E, van Wee R, Kirschbaum C, Kukura P, Robinson CV
January 2024 | Journal article | iScience | Read
Enhanced Antimalarial and Antisequestration Activity of Methoxybenzenesulfonate-Modified Biopolymers and Nanoparticles for Tackling Severe Malaria
Najer A, Kim J, Saunders C, Che J, Baum J, Stevens MM
January 2024 | Journal article | ACS Infectious Diseases | Read
4D Multi-Material Printing of Soft Actuators with Spatial and Temporal Control
Zhou K, Sun R, Wojciechowski JP, Wang R, Yeow J, Zuo Y, Song X, Wang C, Shao Y, Stevens MM
January 2024 | Journal article | Advanced Materials | Read
IL-33-binding HpARI Family Homologues with Divergent Effects in Suppressing or Enhancing Type 2 Immune Responses
Colomb F, Ogunkanbi A, Jamwal A, Dong B, Maizels RM, Finney CAM, Wasmuth JD, Higgins MK, McSorley HJ
January 2024 | Journal article | Infection and Immunity | Read
Regulation of Inositol 5-phosphatase Activity by the C2 Domain of SHIP1 and SHIP2
Bradshaw WJ, Kennedy EC, Moreira T, Smith LA, Chalk R, Katis VL, Benesch JLP, Brennan PE, Murphy EJ, Gileadi O
January 2024 | Journal article | Structure | Read
Data-independent Acquisition Proteomics of Cerebrospinal Fluid Implicates Endoplasmic Reticulum and Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis.
Dellar ER, Vendrell I, Talbot K, Kessler BM, Fischer R, Turner MR, Thompson AG
December 2023 | Journal article | Journal of Neurochemistry | Read
Mass Spectrometry in Cerebrospinal Fluid Uncovers Association of Glycolysis Biomarkers with Alzheimer's Disease in a Large Clinical Sample.
de Geus MB, Leslie SN, Lam T, Wang W, Roux-Dalvai F, Droit A, Kivisakk P, Nairn AC, Arnold SE, Carlyle BC
December 2023 | Journal article | Scientific Reports | Read
Mutant GGGGCC RNA Prevents YY1 from Binding to Fuzzy Promoter which Stimulates Wnt/β-catenin Pathway in C9ALS/FTD.
Chen ZS, Ou M, Taylor S, Dafinca R, Peng SI, Talbot K, Chan HYE
December 2023 | Journal article | Nature Communications | Read
Mechanisms of aquaporin-4 Vesicular Trafficking in Mammalian Cells.
Markou A, Kitchen P, Aldabbagh A, Repici M, Salman MM, Bill RM, Balklava Z
December 2023 | Journal article | Journal of Neurochemistry | Read
Correction: Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-deficient Neurons.
Hasan S, Fernandopulle MS, Humble SW, Frankenfield AM, Li H, Prestil R, Johnson KR, Ryan BJ, Wade-Martins R, Ward ME, Hao L
December 2023 | Journal article | Molecular Neurodegeneration | Read
The PfRCR Complex Bridges Malaria Parasite and Erythrocyte During Invasion.
Farrell B, Alam N, Hart MN, Jamwal A, Ragotte RJ, Walters-Morgan H, Draper SJ, Knuepfer E, Higgins MK
December 2023 | Journal article | Nature | Read
Multilayer DNA Origami with Terminal Interfaces That Are Flat and Wide-Area.
Kilwing L, Lill P, Nathwani B, Guerra R, Benson E, Liedl T, Shih WM
December 2023 | Journal article | ACS Nano | Read
Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease.
Yan S, Jiang C, Janzen A, Barber TR, Seger A, Sommerauer M, Davis JJ, Marek K, Hu MT, Oertel WH, Tofaris GK
December 2023 | Journal article | JAMA Neurology | Read
Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-deficient Neurons.
Hasan S, Fernandopulle MS, Humble SW, Frankenfield AM, Li H, Prestil R, Johnson KR, Ryan BJ, Wade-Martins R, Ward ME, Hao L
November 2023 | Journal article | Molecular Neurodegeneration | Read
Aberrant Topologies of Bacterial Membrane Proteins Revealed by High Sensitivity Fluorescence Labelling.
Hickman SJ, Miller HL, Bukys A, Kapanidis AN, Berks BC
November 2023 | Journal article | Journal of Molecular Biology | Read
Molecular Basis for Selective Uptake and Elimination of Organic Anions in the Kidney by OAT1.
Parker JL, Kato T, Kuteyi G, Sitsel O, Newstead S
November 2023 | Journal article | Nature Structural & Molecular Biology | Read
Penguins Snatch Seconds-long Microsleeps.
Harding CD, Vyazovskiy VV
November 2023 | Journal article | Science | Read
Deep Learning and Single-cell Phenotyping for Rapid Antimicrobial Susceptibility Detection in Escherichia coli.
Zagajewski A, Turner P, Feehily C, El Sayyed H, Andersson M, Barrett L, Oakley S, Stracy M, Crook D, Nellåker C, Stoesser N, Kapanidis AN
November 2023 | Journal article | Communications Biology | Read
Methodological Considerations in Neuronal Extracellular Vesicle Isolation for α-synuclein Biomarkers.
Yan S, Jiang C, Davis JJ, Tofaris GK
November 2023 | Journal article | Brain | Read
Brain Stimulation Techniques as Novel Treatment Options for Insomnia: A Systematic Review.
Krone LB, Fehér KD, Rivero T, Omlin X
November 2023 | Journal article | Journal of Sleep Research | Read
Trypanosomes and Complement: More Than One Way to Die?
Cook AD, Carrington M, Higgins MK
November 2023 | Journal article | Trends in Parasitology | Read
Biocatalytic Reductive Amination as a Route to Isotopically Labelled Amino Acids Suitable for Analysis of Large Proteins by NMR.
Rowbotham JS, Nicholson JH, Ramirez MA, Urata K, Todd PMT, Karunanithy G, Lauterbach L, Reeve HA, Baldwin AJ, Vincent KA
November 2023 | Journal article | Chemical Science | Read
Innovative Method for Rapid Detection of Falsified COVID-19 Vaccines through Unopened Vials Using Handheld Spatially Offset Raman Spectroscopy (SORS).
Mosca S, Lin Q, Stokes R, Bharucha T, Gangadharan B, Clarke R, Fernandez LG, Deats M, Walsby-Tickle J, Arman BY, Chunekar SR, Patil KD, Gairola S, Van Assche K, Dunachie S, Merchant HA, Kuwana R, Maes A, McCullagh J, Caillet C, Zitzmann N, Newton PN, Matousek P
October 2023 | Journal article | Vaccine | Read
Erythrocyte Invasion-neutralising Antibodies Prevent Plasmodium Falciparum RH5 from Binding to Basigin-containing Membrane Protein Complexes.
Jamwal A, Constantin CF, Hirschi S, Henrich S, Bildl W, Fakler B, Draper SJ, Schulte U, Higgins MK
October 2023 | Journal article | Elife | Read
A Quinolin-8-ol Sub-millimolar Inhibitor of UGGT, the ER Glycoprotein Folding Quality Control Checkpoint.
Guay KP, Ibba R, Kiappes JL, Vasiljević S, Bonì F, De Benedictis M, Zeni I, Le Cornu JD, Hensen M, Chandran AV, Kantsadi AL, Caputo AT, Blanco Capurro JI, Bayo Y, Hill JC, Hudson K, Lia A, Brun J, Withers SG, Martí M, Biasini E, Santino A, De Rosa M, Milani M, Modenutti CP, Hebert DN, Zitzmann N, Roversi P
October 2023 | Journal article | iScience | Read
Structural Basis for Triacylglyceride Extraction from Mycobacterial Inner Membrane by MFS Transporter Rv1410.
Remm S, De Vecchis D, Schöppe J, Hutter CAJ, Gonda I, Hohl M, Newstead S, Schäfer LV, Seeger MA
October 2023 | Journal article | Nature Communications | Read
Single Particle Chemical Characterisation of Nanoformulations for Cargo Delivery.
Saunders C, de Villiers CA, Stevens MM
October 2023 | Journal article | The AAPS Journal | Read
Patient-derived iPSC Models of Friedreich Ataxia: A New Frontier for Understanding Disease Mechanisms and Therapeutic Application.
Maheshwari S, Vilema-Enríquez G, Wade-Martins R
September 2023 | Journal article | Translational Neurodegeneration | Read
A New Twist on PIFE: Photoisomerisation-related Fluorescence Enhancement.
Ploetz E, Ambrose B, Barth A, Börner R, Erichson F, Kapanidis AN, Kim HD, Levitus M, Lohman TM, Mazumder A, Rueda D, Steffen FD, Cordes T, Magennis S, Lerner E
September 2023 | Journal article | Methods and Applications in Fluorescence | Read
Trypanosomes and Complement: More than One Way to Die?
Cook AD, Carrington M, Higgins MK
September 2023 | Journal article | Trends in Parasitology | Read
Astrocytes in Functional Recovery Following Central Nervous System Injuries.
Alhadidi QM, Bahader GA, Arvola O, Kitchen P, Shah ZA, Salman MM
September 2023 | Journal article | The Journal of Physiology | Read
PRMT Inhibitor Promotes SMN2 Exon 7 Inclusion and Synergizes with Nusinersen to Rescue SMA Mice.
Kordala AJ, Stoodley J, Ahlskog N, Hanifi M, Garcia Guerra A, Bhomra A, Lim WF, Murray LM, Talbot K, Hammond SM, Wood MJ, Rinaldi C
September 2023 | Journal article | EMBO Molecular Medicine | Read
C9orf72-ALS Human iPSC Microglia are Pro-inflammatory and Toxic to Co-cultured Motor Neurons via MMP9.
Vahsen BF, Nalluru S, Morgan GR, Farrimond L, Carroll E, Xu Y, Cramb KML, Amein B, Scaber J, Katsikoudi A, Candalija A, Carcolé M, Dafinca R, Isaacs AM, Wade-Martins R, Gray E, Turner MR, Cowley SA, Talbot K
September 2023 | Journal article | Nature Communications | Read
Mitochondrial Dysfunction and Mitophagy Defects in LRRK2-R1441C Parkinson's Disease Models.
Williamson MG, Madureira M, McGuinness W, Heon-Roberts R, Mock ED, Naidoo K, Cramb KML, Caiazza MC, Malpartida AB, Lavelle M, Savory K, Humble SW, Patterson R, Davis JB, Connor-Robson N, Ryan BJ, Wade-Martins R
September 2023 | Journal article | Human Molecular Genetics | Read
Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors.
Lutomski CA, El-Baba TJ, Hinkle JD, Liko I, Bennett JL, Kalmankar NV, Dolan A, Kirschbaum C, Greis K, Urner LH, Kapoor P, Yen HY, Pagel K, Mullen C, Syka JEP, Robinson CV
September 2023 | Journal article | Angewandte Chemie | Read
Generation of Two Induced Pluripotent Stem Cell Lines and the Corresponding Isogenic Controls from Parkinson's Disease Patients Carrying the Heterozygous Mutations c.815G > A (p.R272Q) or c.1348C > T (p.R450C) in the RHOT1 Gene Encoding Miro1.
Chemla A, Arena G, Onal G, Walter J, Berenguer-Escuder C, Grossmann D, Grünewald A, Schwamborn JC, Krüger R
September 2023 | Journal article | Stem Cell Research | Read
The Dual Action of Human Antibodies Specific to Plasmodium Falciparum PfRH5 and PfCyRPA: Blocking Invasion and Inactivating Extracellular Merozoites.
Weiss GE, Ragotte RJ, Quinkert D, Lias AM, Dans MG, Boulet C, Looker O, Ventura OD, Williams BG, Crabb BS, Draper SJ, Gilson PR
September 2023 | Journal article | PLoS Pathogens | Read
Modulation and Regulation of Canonical Transient Receptor Potential 3 (TRPC3) Channels.
Cole BA, Becker EBE
September 2023 | Journal article | Cells | Read
Structural Characterization of Human Urea Transporters UT-A and UT-B and Their Inhibition.
Chi G, Dietz L, Tang H, Snee M, Scacioc A, Wang D, Mckinley G, Mukhopadhyay SMM, Pike ACW, Chalk R, Burgess-Brown NA, Timmermans JP, van Putte W, Robinson CV, Dürr KL
September 2023 | Journal article | Science Advances | Read
Continuous Home Cage Monitoring of Activity and Sleep in Mice During Repeated Paroxetine Treatment and Discontinuation.
Collins HM, Pinacho R, Tam SKE, Sharp T, Bannerman DM, Peirson SN
August 2023 | Journal article | Psychopharmacology | Read
Correction to "Cerebrospinal Fluid and Brain Proteoforms of the Granin Neuropeptide Family in Alzheimer's Disease".
Quinn JP, Ethier EC, Novielli A, Malone A, Ramirez CE, Salloum L, Trombetta BA, Kivisäkk P, Bremang M, Selzer S, Fournier M, Das S, Xing Y, Arnold SE, Carlyle BC
August 2023 | Journal article | Journal of the American Society for Mass Spectrometry | Read
Transcending Markov: Non-Markovian Rate Processes of Thermosensitive TRP Ion Channels.
Ben-Abu Y, Tucker SJ, Contera S
August 2023 | Journal article | Royal Society Open Sci | Read
Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.
Burnap SA, Ortega-Prieto AM, Jimenez-Guardeño JM, Ali H, Takov K, Fish M, Shankar-Hari M, Giacca M, Malim MH, Mayr M
August 2023 | Journal article | Molecular & Cellular Proteomics | Read
Advantages of Routine Next-generation Sequencing Over Standard Genetic Testing in the Amyotrophic Lateral Sclerosis Clinic.
Scaber J, Thompson AG, Farrimond L, Feneberg E, Proudfoot M, Ossher L, Turner MR, Talbot K
August 2023 | Journal article | European Journal of Neuralogy | Read
RNA Polymerase Redistribution Supports Growth in E. coli Strains with a Minimal Number of rRNA Operons.
Fan J, El Sayyed H, Pambos OJ, Stracy M, Kyropoulos J, Kapanidis AN
August 2023 | Journal article | Nucleic Acids Research | Read
A Quantitative Description for Optical Mass Measurement of Single Biomolecules.
Becker J, Peters JS, Crooks I, Helmi S, Synakewicz M, Schuler B, Kukura P
August 2023 | Journal article | ACS Photonics | Read
Superior Antibody Immunogenicity of a Viral-vectored RH5 Blood-stage Malaria Vaccine in Tanzanian Infants as Compared to Adults.
Silk SE, Kalinga WF, Mtaka IM, Lilolime NS, Mpina M, Milando F, Ahmed S, Diouf A, Mkwepu F, Simon B, Athumani T, Rashid M, Mohammed L, Lweno O, Ali AM, Nyaulingo G, Mwalimu B, Mswata S, Mwamlima TG, Barrett JR, Wang LT, Themistocleous Y, King LDW, Hodgson SH, Payne RO, Nielsen CM, Lawrie AM, Nugent FL, Cho JS, Long CA, Miura K, Draper SJ, Minassian AM, Olotu AI
August 2023 | Journal article | Clinical Advances | Read
The Solute Carrier SPNS2 Recruits PI(4,5)P2 to Synergistically Regulate Transport of Sphingosine-1-Phosphate.
Tang H, Li H, Prakaash D, Pedebos C, Qiu X, Sauer DB, Khalid S, Duerr K, Robinson CV
August 2023 | Journal article | Molecular Science | Read
Structural Basis of Telomeric Nucleosome Recognition by Shelterin Factor TRF1.
Hu H, van Roon AM, Ghanim GE, Ahsan B, Oluwole AO, Peak-Chew SY, Robinson CV, Nguyen THD
August 2023 | Journal article | Science Advances | Read
ProSight Native: Defining Protein Complex Composition from Native Top-Down Mass Spectrometry Data.
Durbin KR, Robey MT, Voong LN, Fellers RT, Lutomski CA, El-Baba TJ, Robinson CV, Kelleher NL
August 2023 | Journal article | Journal of Proteome Research | Read
A Review of Broadly Protective Monoclonal Antibodies to Treat Ebola Virus Disease.
Rijal P, Donnellan FR
August 2023 | Journal article | Current Opinion in Virology | Read
Impaired Dopamine Release in Parkinson's Disease.
Cramb KML, Beccano-Kelly D, Cragg SJ, Wade-Martins R
August 2023 | Journal article | Brain | Read
Visualization of Direct and Diffusion-assisted RAD51 Nucleation by Full-length Human BRCA2 Protein.
Belan O, Greenhough L, Kuhlen L, Anand R, Kaczmarczyk A, Gruszka DT, Yardimci H, Zhang X, Rueda DS, West SC, Boulton SJ
July 2023 | Journal article | Molecular Cell | Read
The Solute Carrier SPNS2 Recruits PI(4,5)P2 to Synergistically Regulate Transport of Sphingosine-1-Phosphate.
Tang H, Li H, Prakaash D, Pedebos C, Qiu X, Sauer DB, Khalid S, Duerr K, Robinson CV
July 2023 | Journal article | Molecular Cell | Read
Molecular Basis for Selective Uptake and Elimination of Organic Anions in the Kidney by OAT1
Parker JL, Kato T, Kuteyi G, Sitsel O, Newstead S
July 2023 | Journal article | Nature Structural & Molecular Biology | Read
Correction: Limitations of Non-polarizable Force Fields in Describing Anion Binding Poses in Non-polar Synthetic Hosts
Seiferth D, Tucker SJ, Biggin PC
July 2023 | Journal article | Physical Chemistry Chemical Physics | Read
The Beauty and Complexity of the Small Heat Shock Proteins: A Report on the Proceedings of the Fourth Workshop on Small Heat Shock Proteins.
Ecroyd H, Bartelt-Kirbach B, Ben-Zvi A, Bonavita R, Bushman Y, Casarotto E, Cecconi C, Lau WCY, Hibshman JD, Joosten J, Kimonis V, Klevit R, Liberek K, McMenimen KA, Miwa T, Mogk A, Montepietra D, Peters C, Rocchetti MT, Saman D, Sisto A, Secco V, Strauch A, Taguchi H, Tanguay M, Tedesco B, Toth ME, Wang Z, Benesch JLP, Carra S
July 2023 | Journal article | Cell Stress and Chaperones | Read
Vaccination with Plasmodium vivax Duffy-binding Protein Inhibits Parasite Growth During Controlled Human Malaria Infection.
Hou MM, Barrett JR, Themistocleous Y, Rawlinson TA, Diouf A, Martinez FJ, Nielsen CM, Lias AM, King LDW, Edwards NJ, Greenwood NM, Kingham L, Poulton ID, Khozoee B, Goh C, Hodgson SH, Mac Lochlainn DJ, Salkeld J, Guillotte-Blisnick M, Huon C, Mohring F, Reimer JM, Chauhan VS, Mukherjee P, Biswas S, Taylor IJ, Lawrie AM, Cho JS, Nugent FL, Long CA, Moon RW, Miura K, Silk SE, Chitnis CE, Minassian AM, Draper SJ
July 2023 | Journal article | Science Translational Medicine | Read
ProSight Native: Defining Protein Complex Composition from Native Top-Down Mass Spectrometry Data.
Durbin KR, Robey MT, Voong LN, Fellers RT, Lutomski CA, El-Baba TJ, Robinson CV, Kelleher NL
July 2023 | Journal article | Journal of Proteome Research | Read
Dimerization of European Robin Cryptochrome 4a.
Hanić M, Antill LM, Gehrckens AS, Schmidt J, Görtemaker K, Bartölke R, El-Baba TJ, Xu J, Koch KW, Mouritsen H, Benesch JLP, Hore PJ, Solov'yov IA
July 2023 | Journal article | The Journal of Physical Chemistry | Read
Calcium Dysregulation Combined with Mitochondrial Failure and Electrophysiological Maturity Converge in Parkinson's iPSC-dopamine Neurons.
Beccano-Kelly DA, Cherubini M, Mousba Y, Cramb KML, Giussani S, Caiazza MC, Rai P, Vingill S, Bengoa-Vergniory N, Ng B, Corda G, Banerjee A, Vowles J, Cowley S, Wade-Martins R
July 2023 | Journal article | iScience | Read
Recent Advances in Membrane Mimetics for Membrane Protein Research.
Young JW
Jun 2023 | Journal article | Biochemical Society Transactions | Read
Bleaching-resistant, Near-continuous Single-molecule Fluorescence and FRET Based on Fluorogenic and Transient DNA Binding.
Kümmerlin M, Mazumder A, Kapanidis AN
Jun 2023 | Journal article | ChemPhysChem | Read
Monitoring α-synuclein Ubiquitination Dynamics Reveals Key Endosomal Effectors Mediating its Trafficking and Degradation.
Zenko D, Marsh J, Castle AR, Lewin R, Fischer R, Tofaris GK
Jun 2023 | Journal article | Science Advances | Read
Mitochondrial Dysfunction and Mitophagy Defects in LRRK2-R1441C Parkinson's Disease Models.
Williamson MG, Madureira M, McGuinness W, Heon-Roberts R, Mock ED, Naidoo K, Cramb KML, Caiazza MC, Belen Malpartida A, Lavelle M, Savory K, Humble SW, Patterson R, Davis JB, Connor-Robson N, Ryan BJ, Wade-Martins R
Jun 2023 | Journal article | Human Molecular Genetics | Read
Effect of Temperature and Nucleotide on the Binding of BiP Chaperone to a Protein Substrate.
Rivera M, Burgos-Bravo F, Engelberger F, Asor R, Lagos-Espinoza MIA, Figueroa M, Kukura P, Ramírez-Sarmiento CA, Baez M, Smith SB, Wilson CAM
Jun 2023 | Journal article | Protein Science | Read
High-throughput Super-resolution Analysis of Influenza Virus Pleomorphism Reveals Insights into Viral Spatial Organization.
McMahon A, Andrews R, Groves D, Ghani SV, Cordes T, Kapanidis AN, Robb NC
Jun 2023 | Journal article | PLoS Pathogens | Read
Cross-linking Mass Spectrometry Uncovers Interactions Between High-density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.
Burnap SA, Ortega-Prieto AM, Jimenez-Guardeño JM, Ali H, Takov K, Fish M, Shankar-Hari M, Giacca M, Malim MH, Mayr M
Jun 2023 | Journal article | Molecular & Cellular Proteomics | Read
Generation of Two Induced Pluripotent Stem Cell Lines and the Corresponding Isogenic Controls from Parkinson's Disease Patients Carrying the Heterozygous Mutations c.815G > A (p.R272Q) or c.1348C > T (p.R450C) in the RHOT1 Gene Encoding Miro1.
Chemla A, Arena G, Onal G, Walter J, Berenguer-Escuder C, Grossmann D, Grünewald A, Schwamborn JC, Krüger R
Jun 2023 | Journal article | Stem Cell Research | Read
RNA polymerase Redistribution Supports Growth in E. coli Strains with a Minimal Number of rRNA Operons.
Fan J, El Sayyed H, Pambos OJ, Stracy M, Kyropoulos J, Kapanidis AN
Jun 2023 | Journal article | Nucleic Acids Research | Read
Limitations of Non-polarizable Force Fields in Describing Anion Binding Poses in Non-polar Synthetic Hosts.
Seiferth D, Tucker SJ, Biggin PC
Jun 2023 | Journal article | Physical Chemistry Chemical Physics | Read
Rationalizing the Optimization of Detergents for Membrane Protein Purification.
Urner LH, Junge F, Fiorentino F, El-Baba TJ, Shutin D, Nölte G, Haag R, Robinson CV
May 2023 | Journal article | Chemistry Europe | Read
Methodological Considerations in Neuronal Extracellular Vesicle Isolation for α-synuclein Biomarkers.
Yan S, Jiang C, Davis JJ, Tofaris GK
May 2023 | Journal article | Brain | Read
Brain Stimulation Techniques as Novel Treatment Options for Insomnia: A Systematic Review.
Krone LB, Fehér KD, Rivero T, Omlin X
May 2023 | Journal article | Journal of Sleep Research | Read
Single-molecule FRET for Virology: 20 Years of Insight into Protein Structure and Dynamics.
Groves D, Hepp C, Kapanidis AN, Robb NC
May 2023 | Journal article | Quarterly Reviews of Biophysics | Read
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.
Bharucha T, Gangadharan B, Kumar A, Myall AC, Ayhan N, Pastorino B, Chanthongthip A, Vongsouvath M, Mayxay M, Sengvilaipaseuth O, Phonemixay O, Rattanavong S, O'Brien DP, Vendrell I, Fischer R, Kessler B, Turtle L, de Lamballerie X, Dubot-Pérès A, Newton PN, Zitzmann N, SEAe Consortium
May 2023 | Journal article | Journal of Proteome Research | Read
α-Synuclein Fibril and Synaptic Vesicle Interactions Lead to Vesicle Destruction and Increased Lipid-Associated Fibril Uptake into iPSC-derived Neurons.
Stephens AD, Villegas AF, Chung CW, Vanderpoorten O, Pinotsi D, Mela I, Ward E, McCoy TM, Cubitt R, Routh AF, Kaminski CF, Kaminski Schierle GS
May 2023 | Journal article | Communications Biology | Read
A Modular RNA Delivery System Comprising Spherical Nucleic Acids Built on Endosome-escaping Polymeric Nanoparticles.
Garcia-Guerra A, Ellerington R, Gaitzsch J, Bath J, Kye M, Varela MA, Battaglia G, Wood MJA, Manzano R, Rinaldi C, Turberfield AJ.
May 2023 | Journal article | Nanoscale Advances | Read
Alternating Magnetic Field-Promoted Nanoparticle Mixing: The On-Chip Immunocapture of Serum Neuronal Exosomes for Parkinson's Disease Diagnostics.
Sharafeldin M, Yan S, Jiang C, Tofaris GK, Davis JJ
May 2023 | Journal article | Analytical Chemistry | Read
Advantages of Routine Next Generation Sequencing Over Standard Genetic Testing in the ALS Clinic.
Scaber J, Thompson AG, Farrimond L, Feneberg E, Proudfoot M, Ossher L, Turner MR, Talbot K
May 2023 | Journal article | Europen Journal of Neurology | Read
G Protein-Coupled Receptor Pharmacology-Insights from Mass Spectrometry
Yen HY, Jazayeri A, Robinson CV
May 2023 | Journal article | Pharmacological Reviews | Read
Temporal Transcriptional Control of Neural Induction in Human Induced Pluripotent Stem Cells
Gupta S, Polit LD, Fitzgerald M, Rowland HA, Murali D, Buckley NJ, Subramaniam S
May 2023 | Journal article | Frontiers in Molecular Neuroscience | Read
Reconfigurable Self-Assembled DNA Devices
Benson E, Bath J
April 2023 | Journal article | Science Robotics | Read
Bleaching-resistant, Near-continuous Single-molecule Fluorescence and FRET Based on Fluorogenic and Transient DNA Binding
Kümmerlin M, Mazumder A, Kapanidis AN
April 2023 | Journal article | Chemphyschem | Read
Reliability and Accuracy of Single-molecule FRET Studies for Characterization of Structural Dynamics and Distances in Proteins
Agam G, Gebhardt C, Popara M, Mächtel R, Folz J, Ambrose B, Chamachi N, Chung SY, Craggs TD, de Boer M, Grohmann D, Ha T, Hartmann A, Hendrix J, Hirschfeld V, Hübner CG, Hugel T, Kammerer D, Kang HS, Kapanidis AN, Krainer G, Kramm K, Lemke EA, Lerner E, Margeat E, Martens K, Michaelis J, Mitra J, Moya Muñoz GG, Quast RB, Robb NC, Sattler M, Schlierf M, Schneider J, Schröder T, Sefer A, Tan PS, Thurn J, Tinnefeld P, van Noort J, Weiss S, Wendler N, Zijlstra N, Barth A, Seidel CAM, Lamb DC, Cordes T
April 2023 | Journal article | Nature Methods | Read
Shapeshifting Bullvalene-linked Vancomycin Dimers as Effective Antibiotics Against Multidrug-resistant Gram-positive Bacteria
Ottonello A, Wyllie JA, Yahiaoui O, Sun S, Koelln RA, Homer JA, Johnson RM, Murray E, Williams P, Bolla JR, Robinson CV, Fallon T, Soares da Costa TP, Moses JE
April 2023 | Journal article | PNAS | Read
Fortuitously Compatible Protein Surfaces Primed Allosteric Control in Cyanobacterial Photoprotection
Steube N, Moldenhauer M, Weiland P, Saman D, Kilb A, Rojas AAR, Garg SG, Schindler D, Graumann PL, Benesch JLP, Bange G, Friedrich T, Hochberg GKA
April 2023 | Journal article | Nature Ecology & Evolution | Read
Cerebrospinal Fluid and Brain Proteoforms of the Granin Neuropeptide Family in Alzheimer's Disease
Quinn JP, Ethier EC, Novielli A, Malone A, Ramirez CE, Salloum L, Trombetta BA, Kivisäkk P, Bremang M, Selzer S, Fournier M, Das S, Xing Y, Arnold SE, Carlyle BC
March 2023 | Journal article | Journal of the American Society for Mass Spectrometry | Read
An in-solution Snapshot of SARS-COV-2 Main Protease Maturation Process and Inhibition
Noske GD, Song Y, Fernandes RS, Chalk R, Elmassoudi H, Koekemoer L, Owen CD, El-Baba TJ, Robinson CV, COVID Moonshot Consortium, Oliva G, Godoy AS
March 2023 | Journal article | Nature Communications | Read
Influence of Electronic Polarization on the Binding of Anions to a Chloride-pumping Rhodopsin
Phan LX, Chamorro VC, Martinez-Seara H, Crain J, Sansom MSP, Tucker SJ
March 2023 | Journal article | Biophysical Journal | Read
A Special Issue of Essays in Biochemistry on Structural Mass Spectrometry
Britt HM, Beveridge R , Calabrese AN
March 2023 | Journal article | Essays Biochem | Read
Uncovering the Role of N-Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry
El-Baba TJ, Lutomski CA, Burnap SA, Bolla JR, Baker LA, Baldwin AJ, Struwe WB, Robinson CV
March 2023 | Journal article | JACS | Read
Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays
Tyrrell BE, Kumar A, Gangadharan B, Alonzi D, Brun J, Hill M, Bharucha T, Bosworth A, Graham V, Dowall S, Miller JL, Zitzmann N
March 2023 | Journal article | Pathogens | Read
A Quantitative Description for Optical Mass Measurement of Single Biomolecules
Becker J, Peters JS, Crooks I, Helmi S, Synakewicz M, Schuler B, Kukura P
March 2023 | Journal article | bioRxiv | Read
Post-translational Proteomics Platform Identifies Neurite Outgrowth Impairments in Parkinson's Disease GBA-N370S Dopamine Neurons
Bogetofte H, Ryan BJ, Jensen P, Schmidt SI, Vergoossen DLE, Barnkob MB, Kiani LN, Chughtai U, Heon-Roberts R, Caiazza MC, McGuinness W, Márquez-Gómez R, Vowles J, Bunn FS, Brandes J, Kilfeather P, Connor JP, Fernandes HJR, Caffrey TM, Meyer M, Cowley SA, Larsen MR, Wade-Martins R
March 2023 | Journal article | Cell Reports | Read
In Conversation with Carol Robinson
Dhillon P, Robinson C.
March 2023 | Journal article | Febs | Read
Effects of Clozapine-N-oxide and Compound 21 on Sleep in Laboratory Mice
Traut J, Mengual JP, Meijer EJ, McKillop LE, Alfonsa H, Hoerder-Suabedissen A, Song SH, Fehér KD, Riemann D, Molnar Z, Akerman CJ, Vyazovskiy VV, Krone LB
March 2023 | Journal article | eLife | Read
Rationalizing the Optimization of Detergents for Membrane Protein Purification
Urner LH, Junge F, Fiorentino F, El-Baba TJ, Shutin D, Nölte G, Haag R, Robinson CV
March 2023 | Journal article | Chemistry | Read
Impaired Dopamine Release in Parkinson’s Disease
Cramb KML, Beccano-Kelly D, Cragg SJ, Wade-Martins R
March 2023 | Journal article | Brain | Read
Mass Spectrometry of Intact Membrane Proteins: Shifting Towards a More Native-like Context
Oluwole A, Shutin D, Bolla JR
February 2023 | Journal article | Essays in Biochemistry | Read
Posttranslational, Site-directed Photochemical Fluorine Editing of Protein Sidechains to Probe Residue Oxidation State via 19F-nuclear Magnetic Resonance
Isenegger PG, Josephson B, Gaunt B, Davy MJ, Gouverneur V, Baldwin AJ, Davis BG
February 2023 | Journal article | Nature Protocols | Read
Detection of Neuronal OFF Periods as Low Amplitude Neural Activity Segments
Harding CD, Guillaumin MCC, Krone LB, Kahn MC, Blanco-Duque C, Mikutta C, Vyazovskiy VV
February 2023 | Journal article | BMC Neuroscience | Read
HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa
Cramb KML, Beccano-Kelly D, Cragg SJ, Wade-Martins R
February 2023 | Journal article | Pharmaceutics | Read
Functional Integrity of Visual Coding Following Advanced Photoreceptor Degeneration
Rodgers J, Hughes S, Lindner M, Allen AE, Ebrahimi AS, Storchi R, Peirson SN, Lucas RJ, Hankins MW
January 2023 | Journal article | Current Biology | Read
Efficiently Computing the Uhlmann Fidelity for Density Matrices
Baldwin AJ and Jones JA
January 2023 | Journal article | Physical Review A | Read
Unconventional Secretion of alpha-synuclein Mediated by Palmitoylated DNAJC5 Oligomers
Wu S, Hernandez Villegas NC, Sirkis DW, Thomas-Wright I, Wade-Martins R, Schekman R
January 2023 | Journal article | eLife | Read
A Dual Detergent Strategy to Capture a Bacterial Outer Membrane Proteome in Peptidiscs for Characterization by Mass Spectrometry and Binding Assays
Young JW, Zhao ZY, Wason IS, van Hoa FD
December 2022 | Journal article | Journal of Proteome Research | Read
“Paradoxical wakefulness” Induced by Psychedelic 5-methoxy-N, N-dimethyltryptamine in Mice
JB Bréant BJB, Mengual JP, Bannerman DM, Sharp T, Vyazovskiy VV
December 2022 | Journal article | Progress in Brain Research | Read
Coalescing Aptamers and Liquid-Crystals for Sensing Applications
Kulabhusana PK, Ray R, Ramachandra SG, Srinivasulu M, Hariharan A, Balaji K, Mani NK
December 2022 | Journal article | Microchemical Journal | Read
Neurons Derived from Individual Early Alzheimer's Disease Patients Reflect Their Clinical Vulnerability
Ng B, Rowland HA, Wei T, Arunasalam K, Hayes EM, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Ffytche D, Gunn RN, Kocagoncu E, Lawson J, Malhotra PA, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Buckley NJ, Cader ZM, Lovestone S, Wade-Martins R
November 2022 | Journal article | Brain Communications | Read
Single-Molecule Trapping and Measurement in a Nanostructured Lipid Bilayer System
Bespalova M, Öz R, Westerlund F, Krishnan M
November 2022 | Journal article | Langmuir | Read
Glycosylated Clusterin Species Facilitate Aβ Toxicity in Human Neurons
Foster EM, Fernandes M, Dangla-Valls A, Hublitz P, Pangalos M, Lovestone S, Ribe EM, Buckley NJ
November 2022 | Journal article | Scientific Reports | Read
Expansion and Neofunctionalization of Actinoporin-like Genes in Mediterranean Mussel (Mytilus galloprovincialis)
Koritnik N, Gerdol M, Šolinc G, Švigelj T, Caserman S, Merzel F, Holden E, Benesch JLP, Trenti F, Guella G, Pallavicini A, Modica MV, Podobnik M, Anderluh G
November 2022 | Journal article | Genome Biology and Evolution | Read
Anionic Lipids Unlock the Gates of Select Ion Channels in the Pacemaker Family
Schmidpeter PAM, Wu D, Rheinberger J, Riegelhaupt PM, Tang H, Robinson CV, Nimigean CM
November 2022 | Journal article | Nature Structural & Molecular Biology | Read
Mass Spectrometry Captures Biased Signalling and Allosteric Modulation of a G-Protein-Coupled Receptor
Yen HY, Liko I, Song W, Kapoor P, Almeida F, Toporowska J, Gherbi K, Hopper JTS, Charlton S, Politis A, Sansom MSP, Jazayeri A, Robinson CV
November 2022 | Journal article | Nature Chemistry | Read
Native Top-Down Mass Spectrometry Reveals a Role for Interfacial Glycans on Therapeutic Cytokine and Hormone Assemblies
Wu D and Robinson CV
November 2022 | Journal article | Angewandte Chemie-International Edition | Read
CryoEM of Endogenous Mammalian V-ATPase Interacting with the TLDc Protein mEAK-7
Tan YZ , Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL
November 2022 | Journal article | Life Science Alliance | Read
Lipids Mediate Supramolecular Outer Membrane Protein Assembly in Bacteria
Webby MN, Oluwole AO, Pedebos C, Inns PG, Olerinyova A, Prakaash D, Housden NG, Benn G, Sun D, Hoogenbook BW, Kukura P, Mohammed S, Robinson CV, Khalid S, Kleanthous C
November 2022 | Journal article | Science Advances | Read
When is a hydrophobic gate not a hydrophobic gate?
Seiferth D, Biggin PC, Tucker SJ
October 2022 | Journal article | Journal of General Physiology | Read
Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models
Ndunge OBA, Kilian N, Salman MM
October 2022 | Journal article | Advanced Science | Read
GPC3-Unc5 Receptor Complex Structure and Role in Cell Migration
Akkermans O, Delloye-Bourgeois C, Peregrina C, Carrasquero-Ordaz M, Kokolaki M, Berbeira-Santana M, Chavent M, Reynaud F, Raj R, Agirre J, Aksu M, White ES, Lowe E, Ben Amar D, Zaballa S, Huo J, Pakos I, McCubbin PTN, Comoletti D, Owens RJ, Robinson CV, Castellani V, Del Toro D, Seiradake E
October 2022 | Journal article | Cell | Read
GPR97 Triggers Inflammatory Processes in Human Neutrophils via a Macromolecular Complex Upstream of PAR2 Activation
Chu TY, Zheng-Gérard C, Huang KY, Chang YC, Chen YW, I KY, Lo YL, Chiang NY, Chen HY, Stacey M, Gordon S, Tseng WY, Sun CY, Wu YM, Pan YS, Huang CH, Lin CY, Chen TC, El Omari K, Antonelou M, Henderson SR, Salama A, Seiradake E & Lin HH
October 2022 | Journal article | Nature Communications | Read
Neurons Derived from Individual Early Alzheimer’s Disease Patients Reflect Their Clinical Vulnerability
Ng B, Rowland HA, Wei T, Arunasalam K, Hayes EM, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Ffytche D, Gunn RN, Kocagoncu E, Lawson J, Malhotra PA, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Buckley NJ, Cader ZM, Lovestone S, Wade-Martins R
October 2022 | Journal article | Brain Communications | Read
Mass Photometry Reveals SARS-CoV-2 Spike Stabilisation to Impede ACE2 Binding Through Altered Conformational Dynamics
Burnap SA, Struwe W
October 2022 | Journal article | Chemical Communications | Read
Gain-of-function Mutations in KCNK3 Cause a Developmental Disorder with Sleep Apnea
Sörmann J, Schewe M, Proks P, Jouen-Tachoire T, Rao S, Riel EB, Agre KE, Begtrup A, Dean J, Descartes M, Fischer J, Gardham A, Lahner C, Mark PR, Muppidi S, Pichurin PN, Porrmann J, Schallner J, Smith K, Straub V, Vasudevan P, Willaert R, Carpenter EP, Rödström KEJ, Hahn MG, Müller T, Baukrowitz T, Hurles ME, Wright CF, Tucker SJ.
October 2022 | Journal article | Nature Genetics | Read
Repressor Element 1-Silencing Transcription Factor Deficiency Yields Profound Hearing Loss Through K(v)7.4 Channel Upsurge in Auditory Neurons and Hair Cells
Zhang H, Li H, Lu M, Wang S, Ma X, Wang F, Liu J, Li X, Yang H, Zhang F, Shen H, Buckley NJ, Gamper N, Yamoah EN, Lv P
September 2022 | Journal article | eLife | Read
Far-Field Electrostatic Signatures of Macromolecular 3D Conformation
Kloes G, Bennett TJD, Chapet-Batlle A, Behjatian A, Turberfield AJ, Krishnan M
September 2022 | Journal article | Nano Letters | Read
Purkinje Cell Patterning—Insights from Single-Cell Sequencing
Apsley EJ, Becker EBE
September 2022 | Journal article | Cells | Read
Structure of the Malaria Vaccine Candidate Pfs48/45 and its Recognition by Transmission Blocking Antibodies
Ko KT, Lennartz F, Mekhaiel D, Guloglu B, Marini A, Deuker DJ, Long CA, Jore MM, Miura K, Biswas S, Higgins MK
September 2022 | Journal article | Nature Communications | Read
Invariant Surface Glycoprotein 65 of Trypanosoma Brucei is a Complement C3 Receptor
Macleod OJS, Cook AD, Webb H, Crow M, Burns R, Redpath M, Seisenberger S, Trevor CE, Peacock L, Schwede A, Kimblin N, Francisco AF, Pepperl J, Rust S, Voorheis P, Gibson W, Taylor MC, Higgins MK, Carrington M
September 2022 | Journal article | Nature Communications | Read
Multiplex Lateral Flow Assay and the Sample Preparation Method for the Simultaneous Detection of Three Marine Toxins
Mills C, Dillon MJ, Kulabhusan PK, Senovilla-Herrero D, Campbell K
September 2022 | Journal article | Environmental Science & Technology | Read
Direct Observation of the Molecular Mechanism Underlying Protein Polymerization
Hundt N, Cole D, Hantke MF, Miller JJ, Struwe WB, Kukura P
August 2022 | Journal article | Science Advances | Read
Structural Basis for Proton Coupled Cystine Transport by Cystinosin
Löbel M, Salphati SP, El Omari K, Wagner A, Tucker SJ, Parker JL, Newstead S
August 2022 | Journal article | Nature Communications | Read
Re-examining Extreme Sleep Duration in Bats: Implications for Sleep Phylogeny, Ecology, and Function
Harding CD, Yovel Y, Peirson SN, Hackett TD, Vyazovskiy VV
August 2022 | Journal article | Sleep | Read
A new class of biological ion-driven rotary molecular motors with 5:2 symmetry
Rieu M, Krutyholowa R, Taylor NMI, Berry RM
August 2022 | Journal article | Frontiers in Microbiology | Read
Invariant Surface Glycoprotein 65 of Trypanosoma Brucei is a Complement C3 Receptor
Macleod OJS, Cook AD, Webb H, Crow M, Burns R, Redpath M, Seisenberger S, Trevor CE, Peacock L, Schwede A, Kimblin N, Francisco AF, Pepperl J, Rust S, Voorheis P, Gibson W, Taylor MC, Higgins MK, Carrington M
August 2022 | Journal article | Nature Communications | Read
Human iPSC Co-culture Model to Investigate the Interaction between Microglia and Motor Neurons
Vahsen BF, Gray E, Candalija A, Cramb KML, Scaber J, Dafinca R, Katsikoudi A, Xu Y, Farrimond L, Wade-Martins R, James WS, Turner MR, Cowley SA, Talbot K
July 2022 | Journal article | Scientific Reports | Read
Pathogen-sugar Interactions Revealed by Universal Saturation Transfer Analysis.
Buchanan CJ, Baldwin A, et al.
July 2022 | Journal article | Science | Read
Influence of Effective Polarization on Ion and Water Interactions within a Biomimetic Nanopore
Phan LX, Lynch CI, Crain J, Sansom MSP, Tucker SJ
June 2022 | Journal article | Biophysical Journal | Read
No Association Between Amygdala Responses to Negative Faces and Depressive Symptoms: Cross-Sectional Data from 28,638 Individuals in the UK Biobank Cohort
Tamm S, Harmer CJ, Schiel J, Holub F, Rutter MK, Spiegelhalder K, Kyle SD
June 2022 | Journal article | The American Journal of Psychiatry | Read
Patched 1 Regulates Smoothened by Controlling Sterol Binding to its Extracellular Cysteine-rich Domain
Kinnebrew M, Woolley RE, Ansell, TB, Byrne, EFX, Frigui S, Luchetti G, Sircar R, Nachtergaele S, Mydock-McGrane L, Krishnan K, Newstead S, Sansom MSP, Covey D, Siebold C, Rohatgi R
June 2022 | Journal article | Science Advances | Read
Cryo-EM Structures of Pentameric Autoinducer-2 Exporter from Escherichia Coli Reveal its Transport Mechanism
Khera R, Mehdipour AR, Bolla JR, Kahnt J, Welsch S, Ermler U, Muenke C, Robinson CV, Hummer G, Xie H
June 2022 | Journal article | The EMBO Journal | Read
Characterising Biomolecular Interactions and Dynamics with Mass Photometry.
Asor R and Kukura P
June 2022 | Journal article | Current Opinion in Chemical Biology | Read
Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease.
Carlyle BC, Kitchen RR, Mattingly Z, Celia AM, Trombetta BA, Das S, Hyman BT, Kivisäkk P, Arnold SE
June 2022 | Journal article | Frontiers in Neurology | Read
Evidence‐informed is not enough: digital therapeutics also need to be evidence‐based.
Espie CA, Firth J, Torous J
June 2022 | Journal article | World Psychiatry | Read
Studies on enmetazobactam clarify mechanisms of widely used beta-lactamase inhibitors.
Lang PA, Raj R, Tumber A, Lohans CT, Rabe P, Robinson CV, Brem JU, Schofield CJ
May 2022 | Journal article | Proceedings of the National Academy of Sciences of the United States of America | Read
Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release.
Burley S, Beccano-Kelly DA, Talbot K, Llana OC, Wade-Martins R
May 2022 | Journal article | Scientific Reports | Read
Multivalent interactions essential for lentiviral integrase function.
Ballandras-Colas A, Chivukula V, Gruszka DT, Shan ZL, Singh PK, Pye VE, McLean RK, Bedwell GJ, Li W, Nans A, Cook NJ, Fadel HJ, Poeschla EM, Griffiths DJ, Vargas J, Taylor IA, Lyumkis D, Yardimci H, Engelman AN, Cherepanov P
May 2022 | Journal article | Nature Communications | Read
Initiation and progression of alpha-synuclein pathology in Parkinson's disease.
Tofaris GK.
April 2022 | Journal article | Cellular and Molecular Life Sciences | Read
Peptidoglycan biosynthesis is driven by lipid transfer along enzyme-substrate affinity gradients.
Oluwole AO, Corey RA, Brown CM, Hernandez-Rocamora VM, Stansfeld PJ, Vollmer W, Bolla JR, Robinson CV
April 2022 | Journal article | Nature Communications | Read
Capturing a rhodopsin receptor signalling cascade across a native membrane.
Chen SY, Getter T, Salom D, Wu D, Quetschlich D, Chorev DS, Palczewski K, Robinson CV
April 2022 | Journal article | Nature | Read
Template-directed conjugation of heterogeneous oligonucleotides to a homobifunctional molecule for programmable supramolecular assembly.
Helmi S, Turberfield AJ
March 2022 | Journal article | Nanoscale | Read
Re-examining extreme sleep duration in bats: implications for sleep phylogeny, ecology, and function.
Harding CD, Yovel Y, Peirson SN, Hackett TD, Vyazovskiy VV
March 2022 | Journal article | Sleep | Read
Ion and water interactions with a biomimetic nanopore: molecular dynamics with effective polarization
Phan LX, Lynch CI, Crain J, Sansom MSP, Tucker SJ
February 2022 | Journal article | Biophysical Journal | Read
An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy.
Huang SG, Jiang C, Mughal MJ, Wang GY, Xing FQ
February 2022 | Journal article | Frontiers in Bioengineering and Biotechnology | Read
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
Ragotte RJ, Pulido D, Lias AM, Quinkert D, Alanine DGW, Jamwal A, Davies H, Nacer A, Lowe ED, Grime G, Illingworth J, Donat, RF, Garman EF, Bowyer, PW, Higgins MK, Draper SJ
February 2022 | Journal article | Nature Communications | Read
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex.
Patil DN, Singh S, Laboute T, Strutzenberg TS, Qiu XY, Wu D, Novick SJ, Robinson CV, Griffin PR, Hunt JF, Izard T, Singh AK, Martemyanov KA
January 2022 | Journal article | Science | Read
Ion currents through Kir potassium channels are gated by anionic lipids.
Jin RT, He ST, Black KA, Clarke OB, Wu D, Bolla JR, Johnson P, Periasamy A, Wardak A, Czabotar P, Colman PM, Robinson CV, Laver D, Smith BJ, Gulbis JM
January 2022 | Journal article | Nature Communications | Read
Recent breakthroughs and future directions in drugging aquaporins.
Salman MM, Kitchen P, Yool AJ, Bill RM
January 2022 | Journal article | Trends in Pharmacological Sciences | Read
Molecular basis for redox control by the human cystine/glutamate antiporter system xc.
Parker JL, Deme JC, Kolokouris D, Kuteyi G, Biggin PC, Lea SM, Newstead S
December 2021 | Journal article | Nature Communications | Read
Biallelic PI4KA variants cause neurological, intestinal and immunological disease
Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla MP, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Melver CW, Cox H, Elawad M, Marton T, Wakeling MN, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Vockley CW, Butte M, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL
December 2021 | Journal article | Brain | Read
Break-ups and make-ups: DNA search and repair.
Lalande E, El Sayyed H
December 2021 | Journal article | Nature Reviews Microbiology | Read
Multiplexed Profiling of Extracellular Vesicles for Biomarker Development.
Jiang C, Fu Y, Liu G, Shu B, Davis J, Tofaris GK
December 2021 | Journal article | Nano-Micro Letters | Read
Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation.
Prince JP, Bolla JR, Fisher GLM, Mäkelä J, Fournier M, Robinson CV, Arciszewska LK, Sherratt DJ
November 2021 | Journal article | Nature Communications | Read
Single molecule mass photometry reveals the dynamic oligomerization of human and plant peroxiredoxins.
Liebthal M, Kushwah MS, Kukura P, Dietz K-J
November 2021 | Journal article | iScience | Read
Effects of ionic strength on gating and permeation of TREK-2 K2P channels
Conrad LJ, Proks P, Tucker SJ
October 2021 | Journal article | Plos One | Read
Mass spectrometry informs the structure and dynamics of membrane proteins involved in lipid and drug transport.
Bolla JR, Fiorentino F, Robinson CV
October 2021 | Journal article | Current Opinion in Structural Biology | Read
Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target
Adams O, Deme JC, Parker JL, Fowler PW, Lea SM, Newstead S
October 2021 | Journal article | Structure | Read
Structural Basis for Silicic Acid Uptake by Higher Plants.
van den Berg B, Pedebos C, Bolla JR, Robinson CV, Baslé A, Khalid S
September 2021 | Journal article | Journal of Molecular Biology | Read
Molecular basis for redox control by the human cystine/glutamate antiporter System xc-
Parker JL, Deme JC, Kolokouris D, Kuteyi G, Biggin PC, Lea SM, Newstead S
August 2021 | Journal article | Read
Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.
Parker JL, Deme JC, Wu Z, Kuteyi G, Huo J, Owens RJ, Biggin PC, Lea SM, Newstead S
August 2021 | Journal article | Science Advances | Read
The molecular basis of regulation of bacterial capsule assembly by Wzc.
Yang Y, Liu J, Clarke BR, Seidel L, Bolla JR, Ward PN, Zhang P, Robinson CV, Whitfield C, Naismith JH
July 2021 | Journal article | Nature Communications | Read
Structural basis of antifolate recognition and transport by PCFT.
Parker JL, Deme JC, Kuteyi G, Wu Z, Huo J, Goldman ID, Owens RJ, Biggin PC, Lea SM, Newstead S
July 2021 | Journal article | Nature | Read
Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target.
Adams O, Deme JC, Parker JL, CRyPTIC Consortium, Fowler PW, Lea SM, Newstead S
June 2021 | Journal article | Structure | Read
Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons.
Tanudjojo B, Shaikh SS, Fenyi A, Bousset L, Agarwal D, Marsh J, Zois C, Heman-Ackah S, Fischer R, Sims D, Melki R, Tofaris GK
June 2021 | Journal article | Nature Communications | Read
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase.
Kaur H, Jakob RP, Marzinek JK, Green R, Imai Y, Bolla JR, Agustoni E, Robinson CV, Bond PJ, Lewis K, Maier T, Hiller S
May 2021 | Journal article | Nature | Read