Dame Carol Robinson
- First director of Kavli INsD
- A chemist trying to understand biology
- Fascinated by membrane proteins
Lindsay Baker
- First fellow of the Kavli INsD
- Loves collaborative research at the interface between disciplines
- Curious about complex molecular relationships in biological membranes, cells and communities
Andrew Baldwin
- Excited to combine cutting edge measurements in NMR, EM and MS to learn more about important biomedical problems
- Intrigued by the good (molecular chaperones), the bad (amyloid and neurodegeneration) and the blobby (phase separation and the role of membrane less organelles in cell biology)
- To be surrounded by such a diverse, dynamic and exciting group of individuals at Kavli INsD is outstanding for both my research group and I
Esther Becker
- Intrigued by the role of the cerebellum in many different brain disorders
- Hoping to build a 'little brain' in a dish
- Excited to collaborate across disciplines to improve understanding and treatments
Justin Benesch
- Developing new biotechnological solutions for protein quantification
- Trying to understand how biophysical considerations mould protein function and history
- Interested in examining protein structure and interactions under mechanical force
Richard Berry
- A physicist trying to understand how life generates movement
- Looking at rotary molecular motors, one at a time
- Excited to build new collaborations at the interface of physics and biology
Noel Buckley
- Exploring the relationship between genotype and neural phenotype
- Currently intrigued by the use of AI to identify changes in cell behaviour
- Kavli INsD offers an opportunity to exploit planned serendipity of a multidisciplinary environment
Zameel Cader
- Head of Translational Molecular Neuroscience Group
- A neuroscientist trying to make drug discovery human-centric
- Awe-struck by the wonders of the brain
Oliver Crook
- Using mass-spectrometry to understand protein-protein interactions at subcellular and atomistic scales
- Exploiting AI to understand and manipulate protein functions
- Discovering how human parasites hijack and exploit their host
Ruxandra Dafinca
- Intrigued by altered protein organisation and interaction in neurodegeneration
- Interested in applying proteomics and imaging to determine how organelle crosstalk drives synaptic degeneration
- Kavli offers an opportunity for me to apply state-of-the-art technologies to resolve complex intracellular changes in stem cell-derived neurons from patients
Nynke Dekker
- Specializing in single-molecule biophysics, focusing on molecular motors that drive processes like DNA and RNA replication.
- Conducting highly multidisciplinary research that merges biological physics, biochemistry, and molecular biology, offering a challenging yet intriguing and rewarding approach.
- Striving for a precise and mechanistic biophysical description of biological processes through innovative concepts, analysis techniques, and instrumentation.
Simon Draper
- An antibody immunologist seeking to understand how humans respond to vaccination
- Fascinated by the complex biology of malaria parasites
- Interested in translating next-generation nanoparticle vaccines for difficult human diseases
Tarick El-Baba
- Intrigued by how proteins self-organise into functional structures deep within the brain
- Hoping to uncover how molecular-level events shape the way humans and mice think and act
- Trying to understand the molecular roots of neurodevelopmental and psychiatric conditions to reimagine how we diagnose and treat them
Hugo Fernandes
- Alzheimer's Society Dementia Research Leader Fellow
- Intrigued by the role of lipids on selective neuronal vulnerability. Using stem-cell models, single cell -omics and CRISPR screens.
- Thrilled about future interdisciplinary collaborations within Kavli.
Russell G. Foster
- Founding Director - Sleep and Circadian Neuroscience Institute (SCNi), Oxford
- Head, Nuffield Laboratory of Ophthalmology
- Fascinated by the regulation and generation of Sleep and Circadian Rhythms
Dominika Gruszka
- A Royal Society and Wellcome Trust Sir Henry Dale Fellow
- A biophysicist exploring chromatin dynamics during DNA replication
- Fascinated by macromolecular machines in biology
Mark W Hankins
- Professor of Visual Neuroscience
- A retinal biologist with an interest in cell signalling and novel photopigments
- Fascinated by human retinal disease and novel regenerative therapies
Matthew Higgins
- EP Abraham Professor of Structural Biology
- Studies how human-infective parasites bind to their human hosts & fascinated by how parasites manipulate the human immune system
- Scientific Director of the CryoEM facility, and increasingly using the power of this technique
Aarti Jagannath
- Circadian biologist
- Intrigued by how natural signals like light and sleep history are encoded at the molecular level
- Enjoys working with cutting edge tech at the Kavli INsD
Achillefs Kapanidis
- Co-Deputy Director of the Kavli Institute for Nanoscience Discovery
- Chemist who uses physics to understand biology; explores protein machines of gene expression and DNA repair
- A single-molecule aficionado of the Kavli Institute
Philipp Kukura
- Trying to understand the physicochemical basis of biomolecular function
- Intrigued to find out how does nature tune equilibria and kinetics to get the desired outcomes?
- Kavli INsD will completely transform the potential outcomes and impact of technology development
Simon D. Kyle
- Focusing on mechanisms linking sleep and circadian rhythm disruption and mental health
- Develop and test treatments for sleep disruption
- Excited to be part of such a multidisciplinary institute
Corinne Lutomski
- Fascinated by how protein composition shapes information processing at membranes
- Developing native mass spectrometry approaches to resolve proteoform-specific interactions
- Interested in defining how changes in protein composition contribute to neurological disorders
Angela Minassian
- Chief Investigator and clinical lead on the blood-stage and transmission blocking malaria vaccine programmes.
- Qualified Consultant in Infectious Diseases and Microbiology.
- Interested in human challenge models of infection.
Simon Newstead
- David Phillips Professor of Molecular Biophysics
- Linking transport and trafficking in the cell, discovering the role of protons in health and disease
- Building networks to tackle new challenges in biomedicine
Joanne Parker
- A biochemist intrigued by transporter mechanisms
- Excited to combine biochemistry, structural and cell biology to understand membrane proteins
- Hoping to develop new avenues to target pathogenic fungi via glycosylation pathways
Stuart Peirson
- Deputy director - Sleep and Circadian Neuroscience Institute (SCNi), Oxford
- A molecular neuroscientist specialising in the effects of light on physiology and behaviour
- Looking forward to collaborative opportunities to study photobiology and molecular mechanisms underlying sleep and circadian rhythms
David Ray
- Co-director - Sleep and Circadian Neuroscience Institute (SCNi), Oxford
- Embedding clock logic in clinical medicine
- Intrigued by clocks and nuclear receptors in inflammation, and energy metabolism
Stephan Rauschenbach
- Developing methods to handle even the largest molecules with atomic precision
- Exploring ultrafast mechano-chemistry occurring during the collision of large ions with surfaces at hyperthermal energies
- Unlocking imaging methods for fragile large biological molecules
Brent Ryan
- Team leader and departmental lecturer at the Department of Physiology, Anatomy and Genetics
- A cellular biologist studying homeostasis and mitophagy in neurodegeneration using high-throughput approaches
- Loves collaborative research, working closely with industrial partners.
Elena Seiradake
- Wellcome Trust Senior Research Fellow
- Loves collaborative interdisciplinary science
- Studies molecules that make our brain work
Dame Molly Stevens
- John Black Professor of Bionanoscience
- Co-Deputy Director of the Kavli Institute for Nanoscience Discovery
- Using innovative bioengineering approaches to solve key problems in regenerative medicine, diagnostics, and therapeutics.
Weston Struwe
- Tutoral Fellow at Worcester College and UKRI Future Leaders Fellow transforming the way we study glycoproteins
- Captivated by carbohydrate complexity and their biomolecular interactions
- Striving to make next-generation drugs via glycoprotein engineering
Kevin Talbot
- Head of the Nuffield Department of Clinical Neurosciences
- A clinician scientist specialising in pre-clinical modelling of neurodegeneration
- Inspired by the opportunity to work with physical scientists to uncover mechanisms of disease
George Tofaris
- MRC Senior Clinical Fellow investigating neurological disease mechanisms
- Intrigued by how proteins aggregate inside cells
- Keen to apply single molecule approaches within the Kavli INsD to study brain diseases
Stephen Tucker
- Director of the OXION PhD Programme
- Fascinated by ion channels and disease
- Interdisciplinary research in membrane protein biophysics
Affiliated Members
Becky Carlyle
- Alzheimer's Research UK Senior Research Fellow
- Interested in combining cellular biology methods with mass-spectrometry to learn more from proteomics of the human brain
- Driven to understand the cellular changes that predispose people to psychiatric and neurodegenerative disease
Jason Chin
- Reprogramming the genetic code of living cells with new chemistry
- Genome synthesis
- Generating new biological function
Madhavi Krishnan
- Developing electrostatic fluidic traps
- Understanding nanoscale interactions in fluids
- Exploring solvent-mediated electrostatic effects
